{"id":56785,"date":"2026-10-15T08:38:05","date_gmt":"2026-10-15T06:38:05","guid":{"rendered":"https:\/\/bioevidencehub.com\/?p=56785"},"modified":"2026-10-24T07:46:19","modified_gmt":"2026-10-24T05:46:19","slug":"%d8%a7%d9%84%d8%a8%d8%b1%d9%88%d8%aa%d9%8a%d9%86-b7-33","status":"publish","type":"post","link":"https:\/\/bioevidencehub.com\/ar\/peptyd-b7-33\/","title":{"rendered":"\u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 B7-33 \u2013 \u0627\u0644\u062a\u0631\u0643\u064a\u0628 \u0627\u0644\u062c\u0632\u064a\u0626\u064a\u060c \u0627\u0644\u062a\u0623\u062b\u064a\u0631 \u0639\u0644\u0649 \u0645\u0633\u062a\u0642\u0628\u0644 RXFP1 \u0648\u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0628\u062d\u062b\u064a\u0629 \u0627\u0644\u0633\u0627\u0628\u0642\u0629"},"content":{"rendered":"<p>B7-33 \u0647\u0648 \u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0635\u0637\u0646\u0627\u0639\u064a \u062a\u0645 \u062a\u0637\u0648\u064a\u0631\u0647 \u0628\u0646\u0627\u0621\u064b 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\u0627\u0644\u0645\u062e\u0627\u0637\u064a \u0641\u064a \u0638\u0644 \u0638\u0631\u0648\u0641 \u0641\u064a \u0627\u0644\u0645\u062e\u062a\u0628\u0631 \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u063a\u064a\u0631 \u0627\u0644\u0645\u0639\u062f\u0644.<\/p>\n<p>\u0641\u064a \u0627\u0644\u0648\u0642\u062a \u0646\u0641\u0633\u0647\u060c \u0623\u0634\u0627\u0631\u0648\u0627 \u0625\u0644\u0649 \u0627\u0644\u062d\u0627\u062c\u0629 \u0625\u0644\u0649 \u0645\u0632\u064a\u062f \u0645\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u062f\u0648\u0627\u0626\u064a\u0629 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0641\u064a \u0638\u0644 \u0638\u0631\u0648\u0641 \u062d\u064a\u0629. <a href=\"https:\/\/doi.org\/10.3390\/ijms24076616\" target=\"_blank\" rel=\"noopener\">3<\/a><\/p>\n<p>\u0644\u0627 \u062a\u0633\u0645\u062d \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0627\u0633\u062a\u0642\u0631\u0627\u0631 \u0641\u064a \u0627\u0644\u0633\u0627\u0626\u0644 \u0627\u0644\u0645\u062e\u0628\u0631\u064a \u0628\u062a\u062d\u062f\u064a\u062f \u0641\u062a\u0631\u0629 \u0646\u0635\u0641 \u0627\u0644\u0639\u0645\u0631 \u0641\u064a \u0627\u0644\u062c\u0633\u0645 \u0627\u0644\u0628\u0634\u0631\u064a\u060c \u0623\u0648 \u0648\u0642\u062a \u0627\u0644\u0639\u0645\u0644\u060c \u0623\u0648 \u0627\u0644\u062c\u062f\u0648\u0644 \u0627\u0644\u0632\u0645\u0646\u064a \u0627\u0644\u0645\u0646\u0627\u0633\u0628 \u0644\u0644\u0625\u0639\u0637\u0627\u0621.<\/p>\n<h2>\u0627\u0644\u062a\u062d\u0642\u064a\u0642\u0627\u062a \u0627\u0644\u0639\u0644\u0645\u064a\u0629 \u062d\u0648\u0644 B7-33 \u2013 \u0627\u0644\u0623\u062f\u0644\u0629 \u0627\u0644\u0645\u062e\u062a\u0628\u0631\u064a\u0629 \u0648\u0627\u0644\u062d\u064a\u0648\u0627\u0646\u064a\u0629 \u0648\u0627\u0644\u0637\u0628\u064a\u0629<\/h2>\n<h3>\u0627\u0644\u062a\u062d\u0642\u064a\u0642\u0627\u062a \u0627\u0644\u0623\u0648\u0644\u0649 \u0641\u064a \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644\u0627\u062a \u0648\u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0644\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u0627\u062a<\/h3>\n<p>\u0623\u0635\u062f\u0631\u062a \u0646\u0634\u0631\u0629 \u0623\u0633\u0627\u0633\u064a\u0629 \u0641\u064a \u0639\u0627\u0645 2016 \u0642\u062f\u0645\u062a \u062a\u0635\u0645\u064a\u0645 B7-33 \u0627\u0644\u0645\u0628\u0633\u0637 \u0648\u0648\u0635\u0641\u062a \u0627\u0644\u0622\u0644\u064a\u0627\u062a \u0627\u0644\u0625\u0634\u0627\u0631\u0627\u062a\u064a\u0629 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0647.<\/p>\n<p>\u0643\u0645\u0627 \u062a\u0645 \u0648\u0635\u0641 \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0641\u064a \u0646\u0645\u0627\u0630\u062c \u062f\u0645\u0627\u063a\u064a\u0629 \u0648\u0623\u0648\u0639\u064a\u0629 \u062f\u0645\u0648\u064a\u0629 \u062a\u062c\u0631\u064a\u0628\u064a\u0629\u060c \u0648\u062a\u0645 \u062a\u062d\u0644\u064a\u0644 \u0646\u0645\u0648\u0630\u062c \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u0628\u0631\u0648\u0633\u062a\u0627\u062a\u0627. <a href=\"https:\/\/doi.org\/10.1039\/c5sc04754d\" target=\"_blank\" rel=\"noopener\">1<\/a><\/p>\n<p>\u062a\u0639\u062a\u0628\u0631 \u0647\u0630\u0647 \u0627\u0644\u0645\u0644\u0627\u062d\u0638\u0627\u062a \u0645\u0628\u0631\u0631\u0627\u064b \u0644\u0625\u062c\u0631\u0627\u0621 \u0627\u0644\u0645\u0632\u064a\u062f \u0645\u0646 \u0627\u0644\u0623\u0628\u062d\u0627\u062b.<\/p>\n<p>\u0648\u0644\u0643\u0646\u0647\u0627 \u0644\u0627 \u062a\u062b\u0628\u062a \u0623\u0646 B7-33 \u064a\u0645\u0646\u0639 \u0627\u0646\u0642\u0633\u0627\u0645 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0644\u062f\u0649 \u0627\u0644\u0628\u0634\u0631\u060c \u0648\u0644\u0627 \u0623\u0646 \u0647\u0646\u0627\u0643 \u062a\u0642\u064a\u064a\u0645\u064b\u0627 \u0634\u0627\u0645\u0644\u064b\u0627 \u0644\u0623\u0645\u0627\u0646\u0647 \u0645\u0646 \u062d\u064a\u062b \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u0627\u0648\u064a.<\/p>\n<p>\u0627\u0644\u062a\u062d\u0642\u064a\u0642\u0627\u062a \u0627\u0644\u0644\u0627\u062d\u0642\u0629 \u0641\u064a \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0621 \u0627\u0644\u0637\u0628\u064a\u0629 \u0642\u062f \u0646\u0638\u0631\u062a \u0641\u064a \u0627\u0644\u062a\u0639\u062f\u064a\u0644\u0627\u062a \u0627\u0644\u062a\u064a \u0637\u0631\u0623\u062a \u0639\u0644\u0649 \u0628\u0646\u064a\u0629 B7-33\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0627\u0644\u0627\u0633\u062a\u0631\u0627\u062a\u064a\u062c\u064a\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0624\u062b\u0631 \u0639\u0644\u0649 \u0627\u0644\u0628\u0646\u064a\u0629 \u0627\u0644\u062b\u0627\u0646\u0648\u064a\u0629 \u0648\u0623\u0646\u0634\u0637\u0629 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0623\u0645\u064a\u0646\u064a.<\/p>\n<p>\u062a\u0633\u0627\u0639\u062f \u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0639\u0644\u0627\u0642\u0629 \u0628\u064a\u0646 \u0627\u0644\u062a\u0631\u0643\u064a\u0628 \u0648\u0627\u0644\u0646\u0634\u0627\u0637 \u0639\u0644\u0649 \u062a\u062d\u062f\u064a\u062f \u0627\u0644\u0639\u0646\u0627\u0635\u0631 \u0627\u0644\u062c\u0632\u064a\u0626\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0624\u062b\u0631 \u0639\u0644\u0649 \u0627\u0644\u0625\u0634\u0627\u0631\u0627\u062a.<\/p>\n<p>\u0648\u0644\u0643\u0646\u0647\u0645 \u0644\u0627 \u064a\u0624\u0643\u062f\u0648\u0646 \u0623\u0646 \u0643\u0644 \u0645\u062b\u064a\u0644 \u0645\u0639\u062f\u0651\u0644 \u064a\u062d\u0627\u0641\u0638 \u0639\u0644\u0649 \u062e\u0635\u0627\u0626\u0635 \u0627\u0644\u062a\u0635\u0645\u064a\u0645 \u0627\u0644\u0623\u0635\u0644\u064a. <a href=\"https:\/\/doi.org\/10.3390\/ijms241612670\" target=\"_blank\" rel=\"noopener\">4<\/a><\/p>\n<h3>\u062f\u0631\u0627\u0633\u0627\u062a \u0639\u0646 \u062a\u0644\u0641 \u0627\u0644\u0642\u0644\u0628 \u0648\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u062e\u0644\u0642\u064a<\/h3>\n<p>\u0641\u064a \u0639\u0627\u0645 2020 \u062a\u0645 \u0646\u0634\u0631 \u062f\u0631\u0627\u0633\u0629 \u0639\u0644\u0649 \u0627\u0644\u0641\u0626\u0631\u0627\u0646 \u062a\u0633\u062a\u062e\u062f\u0645 \u0646\u0645\u0648\u0630\u062c \u0646\u0642\u0635 \u0627\u0644\u062a\u0631\u0648\u064a\u0629 \u0648\u0625\u0639\u0627\u062f\u0629 \u0627\u0644\u062a\u063a\u0630\u064a\u0629.<\/p>\n<p>\u0628\u0639\u062f \u0627\u0633\u062a\u062e\u062f\u0627\u0645 B7-33 \u0627\u0644\u062a\u062c\u0631\u064a\u0628\u064a\u060c \u0644\u0648\u062d\u0638 \u062a\u062d\u0633\u0646 \u0641\u064a \u0645\u0639\u0644\u0645\u0627\u062a \u0627\u0644\u0636\u0631\u0631 \u0648\u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u0642\u0644\u0628.<\/p>\n<p>\u0627\u0644\u062e\u0628\u0631\u0627\u062a \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0643\u062a\u0641\u064a\u0627\u062a \u0627\u0644\u0642\u0644\u0628 \u062a\u062a\u0646\u0627\u0648\u0644 \u0622\u0644\u064a\u0627\u062a \u0627\u0644\u0627\u0633\u062a\u062c\u0627\u0628\u0629 \u0627\u0644\u062e\u0644\u0648\u064a\u0629 \u0644\u0644\u0625\u062c\u0647\u0627\u062f. <a href=\"https:\/\/doi.org\/10.1161\/JAHA.119.015748\" target=\"_blank\" rel=\"noopener\">5<\/a><\/p>\n<p>\u064a\u064f\u0645\u062b\u0644 \u0646\u0645\u0648\u0630\u062c \u0646\u0642\u0635 \u0627\u0644\u062f\u0645 \u0648\u0625\u0639\u0627\u062f\u0629 \u0627\u0644\u062a\u063a\u0630\u064a\u0629 \u0628\u0639\u0636 \u062c\u0648\u0627\u0646\u0628 \u062a\u0644\u0641 \u0639\u0636\u0644\u0629 \u0627\u0644\u0642\u0644\u0628 \u0641\u064a \u0638\u0644 \u0638\u0631\u0648\u0641 \u0645\u0639\u0627\u0644\u062c\u0629 \u0645\u062d\u062f\u062f\u0629.<\/p>\n<p>\u0648\u0644\u0643\u0646\u0647 \u0644\u0627 \u064a\u062a\u064a\u062d \u062a\u062d\u062f\u064a\u062f \u0645\u0627 \u0625\u0630\u0627 \u0643\u0627\u0646 B7-33 \u064a\u0633\u0631\u0651\u0639 \u0645\u0639\u062f\u0644 \u0634\u0641\u0627\u0621 \u0627\u0644\u0645\u0631\u0636\u0649 \u0628\u0639\u062f \u0646\u0648\u0628\u0629 \u0642\u0644\u0628\u064a\u0629.<\/p>\n<p>\u0641\u064a \u062f\u0631\u0627\u0633\u0629 \u0623\u062e\u0631\u0649\u060c \u062a\u0645 \u0645\u0642\u0627\u0631\u0646\u0629 B7-33 \u0645\u0639 \u0627\u0644\u0631\u0644\u064a\u0643\u0633\u064a\u0646 \u0648\u0627\u0644\u0628\u064a\u0631\u0646\u062f\u0648\u0628\u0631\u064a\u0644 \u0641\u064a \u0646\u0645\u0648\u0630\u062c \u062d\u064a\u0648\u0627\u0646\u064a \u0644\u0644\u0642\u0644\u064a\u0629 \u0627\u0644\u0642\u0644\u0628\u064a\u0629.<\/p>\n<p>\u062a\u0645 \u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u062a\u0635\u0644\u0628 \u0648\u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u0642\u0644\u0628 \u0645\u0639 \u0645\u0639\u0644\u0645\u0627\u062a \u0645\u062e\u062a\u0627\u0631\u0629. <a href=\"https:\/\/doi.org\/10.1016\/j.biopha.2023.114370\" target=\"_blank\" rel=\"noopener\">6<\/a><\/p>\n<p>\u0647\u0630\u0647 \u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0627\u062a \u0645\u0641\u064a\u062f\u0629 \u0641\u064a \u062d\u062f\u0648\u062f \u0627\u0644\u0646\u0645\u0648\u0630\u062c \u0627\u0644\u062a\u062c\u0631\u064a\u0628\u064a \u0627\u0644\u0645\u0633\u062a\u062e\u062f\u0645.<\/p>\n<p>\u0625\u0644\u0627 \u0623\u0646 \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0644\u0627 \u062a\u0634\u0643\u0644 \u062f\u0631\u0627\u0633\u0627\u062a \u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0628\u0627\u0634\u0631\u0629 \u0644\u062f\u0649 \u0627\u0644\u0628\u0634\u0631 \u0648\u0644\u0627 \u062a\u0624\u0643\u062f \u0639\u0644\u0649 \u062a\u0641\u0648\u0642 B7-33 \u0639\u0644\u0649 \u0627\u0644\u0637\u0631\u0642 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0629 \u0627\u0644\u0645\u0639\u062a\u0645\u062f\u0629.<\/p>\n<h3>\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0648\u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629<\/h3>\n<p>\u062a\u0634\u064a\u0631 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0625\u0644\u0649 \u0623\u0646 \u0627\u0644\u0627\u0633\u062a\u062c\u0627\u0628\u0629 \u0644\u0640 B7-33 \u0642\u062f \u062a\u062e\u062a\u0644\u0641 \u062a\u0628\u0639\u0627\u064b \u0644\u0646\u0648\u0639 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u062a\u064a \u064a\u062a\u0645 \u062a\u062d\u0644\u064a\u0644\u0647\u0627.<\/p>\n<p>\u0641\u064a \u062a\u062c\u0627\u0631\u0628 \u0645\u0639\u064a\u0646\u0629\u060c \u0644\u0648\u062d\u0638\u062a \u0622\u062b\u0627\u0631 \u0645\u0641\u064a\u062f\u0629 \u0641\u064a \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0627\u0644\u0643\u0631\u064a\u0648\u0633\u062a\u064a\u0643\u064a\u0629\u060c \u0648\u0644\u0643\u0646 \u0644\u0645 \u064a\u062a\u0645 \u062a\u062d\u062f\u064a\u062f \u0627\u0633\u062a\u062c\u0627\u0628\u0629 \u0639\u0627\u0645\u0629 \u0645\u0645\u0627\u062b\u0644\u0629 \u0641\u064a \u062c\u0645\u064a\u0639 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062a\u064a \u062e\u0636\u0639\u062a \u0644\u0644\u0627\u062e\u062a\u0628\u0627\u0631.<\/p>\n<p>\u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0625\u0636\u0627\u0641\u064a\u0629 \u0627\u0644\u062a\u064a \u0627\u0633\u062a\u062e\u062f\u0645\u062a \u0648\u0633\u064a\u0644\u0629 \u062a\u0645 \u062a\u0643\u064a\u064a\u0641\u0647\u0627 \u0628\u0648\u0627\u0633\u0637\u0629 \u062e\u0644\u064a\u0629 \u0627\u0644\u062a\u0644\u0642\u064a\u062d \u0627\u0644\u0645\u062c\u0647\u0631\u064a (trofoblast) \u0648\u0623\u0648\u0639\u064a\u0629 \u062f\u0645\u064a\u0629 \u0645\u0639\u0632\u0648\u0644\u0629 \u0645\u0646 \u0627\u0644\u0641\u0626\u0631\u0627\u0646\u060c \u0631\u0643\u0632\u062a \u0639\u0644\u0649 \u062e\u0644\u0644 \u0641\u064a \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629. \u0644\u0643\u0646\u0647\u0627 \u0644\u0645 \u062a\u0634\u0645\u0644 \u0639\u0644\u0627\u062c \u0627\u0644\u0646\u0633\u0627\u0621 \u0627\u0644\u062d\u0648\u0627\u0645\u0644. <a href=\"https:\/\/doi.org\/10.1016\/j.ejphar.2017.05.005\" target=\"_blank\" rel=\"noopener\">7<\/a><\/p>\n<p>\u0648\u0644\u0630\u0644\u0643\u060c \u064a\u062c\u0628 \u0639\u0631\u0636 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0639\u0644\u0649 \u0623\u0646\u0647\u0627 \u0645\u0644\u0627\u062d\u0638\u0627\u062a \u0645\u0645\u064a\u0632\u0629 \u0644\u0641\u0631\u0627\u062f\u0649 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u0646\u0633\u064a\u062c\u064a\u0629 \u0648\u0627\u0644\u0646\u0645\u0627\u0630\u062c \u0627\u0644\u0628\u062d\u062b\u064a\u0629.<\/p>\n<p>\u0648\u0644\u0643\u0646\u0647\u0627 \u0644\u0627 \u062a\u0624\u0643\u062f \u0627\u0644\u062d\u0645\u0627\u064a\u0629 \u0627\u0644\u0634\u0627\u0645\u0644\u0629 \u0644\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0648\u0644\u0627 \u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u0627\u0644\u0625\u0646\u062c\u0627\u0628\u064a\u0629.<\/p>\n<h3>\u062a\u0635\u0644\u0628 \u0627\u0644\u0643\u0644\u064a\u062a\u064a\u0646 \u0648\u062a\u0646\u062f\u0628 \u062d\u0648\u0644 \u0627\u0644\u0623\u062c\u0647\u0632\u0629 \u0627\u0644\u0645\u0632\u0648\u062f\u0629 \u0628\u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629<\/h3>\n<p>\u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0645\u062a\u0639\u0644\u0642\u0629 \u0628\u062a\u0635\u0644\u0628 \u0627\u0644\u0643\u0644\u064a\u062a\u064a\u0646 \u0644\u062f\u0649 \u0627\u0644\u0641\u0626\u0631\u0627\u0646\u060c \u062a\u0645 \u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u062a\u063a\u064a\u0631\u0627\u062a \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0640 B7-33\u060c \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0641\u064a \u0627\u0644\u0648\u0642\u062a \u0646\u0641\u0633\u0647 \u0628\u064a\u0646 \u0637\u0631\u0642 \u0642\u064a\u0627\u0633 \u0627\u0644\u0643\u0648\u0644\u0627\u062c\u064a\u0646 \u0627\u0644\u0645\u062e\u062a\u0644\u0641\u0629. <a href=\"https:\/\/doi.org\/10.1096\/fj.202002053RRR\" target=\"_blank\" rel=\"noopener\">8<\/a><\/p>\n<p>\u064a\u0634\u0631\u062d \u0627\u0644\u0628\u062d\u062b \u0643\u0644 \u0645\u0646 \u0627\u0644\u0646\u0634\u0627\u0637 \u0627\u0644\u0645\u0636\u0627\u062f \u0644\u0644\u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0645\u062d\u062a\u0645\u0644 \u0648\u0636\u0631\u0648\u0631\u0629 \u0627\u062e\u062a\u064a\u0627\u0631 \u0637\u0631\u064a\u0642\u0629 \u0642\u064a\u0627\u0633 \u0645\u0646\u0627\u0633\u0628\u0629.<\/p>\n<p>\u0644\u0627 \u064a\u062c\u0628 \u0623\u0646 \u062a\u062a\u063a\u064a\u0631 \u0643\u0645\u064a\u0629 \u0627\u0644\u0643\u0648\u0644\u0627\u062c\u064a\u0646 \u0648\u062a\u0648\u0632\u0639\u0647\u0627 \u0648\u0648\u0638\u064a\u0641\u0629 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0628\u0634\u0643\u0644 \u0645\u062a\u0632\u0627\u0645\u0646.<\/p>\n<p>\u0641\u064a \u0645\u0634\u0631\u0648\u0639 B7-33 \u0627\u0644\u0622\u062e\u0631\u060c \u062a\u0645 \u062a\u0636\u0645\u064a\u0646 \u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u0644\u062f\u0627\u0626\u0646 \u0627\u0644\u0645\u0635\u0645\u0645\u0629 \u0644\u0625\u0641\u0631\u0627\u0632 \u0627\u0644\u0628\u0628\u062a\u064a\u062f \u0641\u064a \u0645\u062d\u064a\u0637 \u0627\u0644\u062c\u0647\u0627\u0632.<\/p>\n<p>\u0648\u0635\u0641 \u0627\u0644\u0639\u0644\u0645\u0627\u0621 \u0627\u0644\u062d\u062f \u0645\u0646 \u062a\u0643\u0648\u064a\u0646 \u0627\u0644\u063a\u0644\u0627\u0641 \u0627\u0644\u0643\u0631\u0648\u064a \u062d\u0648\u0644 \u0627\u0644\u0623\u062c\u0647\u0632\u0629 \u0627\u0644\u0645\u0632\u0648\u062f\u0629 \u0628\u0627\u0644\u0632\u0631\u0639 \u0644\u062f\u0649 \u0627\u0644\u0641\u0626\u0631\u0627\u0646. <a href=\"https:\/\/doi.org\/10.1021\/acsami.9b17859\" target=\"_blank\" rel=\"noopener\">9<\/a><\/p>\n<p>\u064a\u062a\u0639\u0644\u0642 \u0647\u0630\u0627 \u0627\u0644\u0646\u062a\u064a\u062c\u0629 \u0628\u0646\u0638\u0627\u0645 \u0627\u0644\u062a\u062d\u0643\u0645 \u0641\u064a \u0627\u0644\u0625\u0641\u0631\u0627\u062c \u0627\u0644\u0645\u062d\u0644\u064a \u0644\u0644\u0645\u0627\u062f\u0629.<\/p>\n<p>\u0644\u0627 \u064a\u0645\u0643\u0646 \u0627\u0633\u062a\u062e\u062f\u0627\u0645\u0647 \u0628\u0634\u0643\u0644 \u0645\u0628\u0627\u0634\u0631 \u0645\u0639 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0641\u0645\u0648\u064a\u0629 \u0623\u0648 \u0627\u0644\u062d\u0642\u0646 \u0623\u0648 \u0645\u0633\u062a\u062d\u0636\u0631\u0627\u062a \u0627\u0644\u062a\u062c\u0645\u064a\u0644 \u062f\u0648\u0646 \u0625\u062c\u0631\u0627\u0621 \u062f\u0631\u0627\u0633\u0627\u062a \u0643\u0627\u0641\u064a\u0629.<\/p>\n<h3>\u062e\u0644\u064a\u0629 \u0627\u0644\u0625\u0646\u0633\u0627\u0646 \u0630\u0627\u062a \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0645\u062a\u0635\u0644\u0628\u0629 \u0648\u0646\u0638\u0645 \u0627\u0644\u062a\u0648\u0635\u064a\u0644 \u0627\u0644\u0645\u062a\u0642\u062f\u0645\u0629 B7-33<\/h3>\n<p>\u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u062a\u064a \u0623\u062c\u0631\u064a\u062a \u0641\u064a \u0639\u0627\u0645 2026\u060c \u062a\u0645 \u062a\u062d\u0644\u064a\u0644 \u0623\u0644\u064a\u0627\u0641 \u0627\u0644\u0628\u0634\u0631\u064a\u0629 \u0627\u0644\u0645\u0633\u062a\u0645\u062f\u0629 \u0645\u0646 \u0646\u062f\u0628\u0627\u062a \u0645\u062a\u0636\u062e\u0645\u0629 \u0648\u0636\u0645\u0627\u062f\u0629 \u0643\u0647\u0631\u0628\u0627\u0626\u064a\u0629 \u062a\u062d\u062a\u0648\u064a \u0639\u0644\u0649 B7-33.<\/p>\n<p>\u0634\u0645\u0644\u062a \u0627\u0644\u0645\u0639\u0644\u0645\u0627\u062a \u0627\u0644\u0645\u0642\u064a\u0651\u0645\u0629 \u0631\u062f\u0648\u062f \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0648\u0627\u0644\u062a\u0639\u0628\u064a\u0631 \u0627\u0644\u062c\u064a\u0646\u064a \u0648\u062e\u0635\u0627\u0626\u0635 \u0646\u0638\u0627\u0645 \u062a\u0648\u0635\u064a\u0644 \u0627\u0644\u0628\u0628\u062a\u064a\u062f. <a href=\"https:\/\/unipv.unifind.cineca.it\/resource\/item\/618128?language=en-US\" target=\"_blank\" rel=\"noopener\">10<\/a><\/p>\n<p>\u0644\u0623\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0633\u062a\u062e\u062f\u0645\u062a \u062e\u0644\u0627\u064a\u0627 \u0645\u0646 \u0627\u0644\u0628\u0634\u0631 \u0648\u0644\u064a\u0633 \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u062e\u0636\u0639\u0648\u0627 \u0644\u0644\u0639\u0644\u0627\u062c\u060c \u0641\u0625\u0646\u0647\u0627 \u0644\u0627 \u062a\u0632\u0627\u0644 \u0623\u062f\u0644\u0629\u064b \u0641\u0644\u0643\u064a\u0629.<\/p>\n<p>\u0644\u0627 \u064a\u062b\u0628\u062a \u0639\u0644\u0645\u064a\u0627\u064b \u0623\u0646 \u0627\u0644\u0636\u0645\u0627\u062f\u0629 \u062a\u062d\u0633\u0646 \u0645\u0638\u0647\u0631 \u0623\u0648 \u0634\u0643\u0644 \u0627\u0644\u0646\u062f\u0628\u0627\u062a \u0644\u062f\u0649 \u0627\u0644\u0628\u0634\u0631.<\/p>\n<p>\u0643\u0645\u0627 \u0642\u0627\u0645 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0628\u062a\u062d\u0644\u064a\u0644 B7-33 \u0645\u0639 \u0627\u0644\u0646\u0627\u0646\u0648\u0630\u0631\u0627\u062a\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0623\u0646\u0638\u0645\u0629 \u0625\u064a\u0635\u0627\u0644 \u0627\u0644\u0628\u0628\u062a\u064a\u062f \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0644\u0641\u0645 \u0627\u0644\u0645\u062a\u062e\u0635\u0635\u0629 \u0627\u0644\u062a\u064a \u062a\u0645 \u062f\u0631\u0627\u0633\u062a\u0647\u0627 \u0639\u0644\u0649 \u0627\u0644\u0641\u0626\u0631\u0627\u0646. <a href=\"https:\/\/doi.org\/10.1186\/s12929-025-01198-8\" target=\"_blank\" rel=\"noopener\">11<\/a><\/p>\n<p>\u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u062a\u062c\u0627\u0631\u0628\u060c \u064a\u0634\u0643\u0644 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\u0627\u0644\u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0648\u0644\u0643\u0646\u0647\u0627 \u0645\u0646\u0641\u0635\u0644\u0629.<\/p>\n<p>\u0644\u0627 \u064a\u0646\u0628\u063a\u064a \u0627\u0644\u062c\u0645\u0639 \u0628\u064a\u0646\u0647\u0645\u0627 \u0641\u064a \u0622\u0644\u064a\u0629 \u062d\u0645\u0627\u064a\u0629 \u0644\u0644\u0623\u0639\u0636\u0627\u0621 \u0648\u0627\u062d\u062f\u0629 \u0645\u0623\u0645\u0648\u0646\u0629 \u062a\u0645\u0627\u0645\u064b\u0627. <a href=\"https:\/\/doi.org\/10.1161\/JAHA.119.015748\" target=\"_blank\" rel=\"noopener\">5<\/a> <a href=\"https:\/\/doi.org\/10.1016\/j.ejphar.2017.05.005\" target=\"_blank\" rel=\"noopener\">7<\/a><\/p>\n<p>\u0639\u0628\u0627\u0631\u062a\u0627\u0646 \u201e\u0645\u0642\u0627\u0648\u0645 \u0644\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u201d \u0648\u201e\u062d\u0627\u0645\u064a \u0644\u0644\u0623\u0646\u0633\u062c\u0629\u201d \u0623\u0643\u062b\u0631 \u062f\u0642\u0629 \u0639\u0646\u062f\u0645\u0627 \u062a\u0643\u0648\u0646 \u0645\u0635\u062d\u0648\u0628\u0629 \u0628\u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0639\u0646 \u0627\u0644\u0646\u0645\u0648\u0630\u062c \u0627\u0644\u062a\u062c\u0631\u064a\u0628\u064a\u060c \u0627\u0644\u0635\u064a\u063a\u0629\u060c \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0645\u0645\u0627\u062b\u0644\u0629 \u0648\u0627\u0644\u0646\u062a\u064a\u062c\u0629 \u0627\u0644\u0641\u0639\u0644\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0645 \u0631\u0635\u062f\u0647\u0627.<\/p>\n<p>\u0625\u0646\u0647\u0627 \u0644\u0627 \u062a\u0639\u0646\u064a \u0625\u0632\u0627\u0644\u0629 \u0627\u0644\u0646\u062f\u0628\u0627\u062a \u0628\u0634\u0643\u0644 \u0645\u0624\u0643\u062f\u060c \u0623\u0648 \u0627\u0644\u062a\u0639\u0627\u0641\u064a \u0627\u0644\u0639\u0627\u0645\u060c \u0623\u0648 \u0627\u0644\u062a\u0639\u0627\u0641\u064a \u0627\u0644\u0633\u0631\u064a\u0639 \u0644\u062f\u0649 \u0627\u0644\u0628\u0634\u0631.<\/p>\n<h2>\u0627\u0644\u0642\u064a\u0648\u062f \u0639\u0644\u0649 \u0627\u0644\u0623\u062f\u0644\u0629 \u0627\u0644\u0639\u0644\u0645\u064a\u0629 \u0627\u0644\u0645\u062a\u0639\u0644\u0642\u0629 \u0628\u0640 B7-33<\/h2>\n<h3>\u0639\u062f\u0645 \u0648\u062c\u0648\u062f \u0641\u0639\u0627\u0644\u064a\u0629 \u0633\u0631\u064a\u0631\u064a\u0629 \u0645\u0639\u062a\u0645\u062f\u0629 \u0644\u062f\u0649 \u0627\u0644\u0628\u0634\u0631<\/h3>\n<p>\u0627\u0644\u0642\u064a\u0648\u062f \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629 \u0647\u064a \u0639\u062f\u0645 \u0648\u062c\u0648\u062f \u0641\u0639\u0627\u0644\u064a\u0629 \u062b\u0627\u0628\u062a\u0629 \u0639\u0644\u0649 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0641\u064a \u0627\u0644\u0623\u062f\u0628\u064a\u0627\u062a \u0627\u0644\u0645\u062a\u0627\u062d\u0629.<\/p>\n<p>\u064a\u0645\u0643\u0646 \u0623\u0646 \u062a\u0624\u0643\u062f \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u062c\u0632\u064a\u0626\u064a\u0629 \u0648\u0627\u0644\u0646\u0645\u0627\u0630\u062c \u0627\u0644\u062d\u064a\u0648\u0627\u0646\u064a\u0629 \u0639\u0644\u0649 \u0627\u0644\u0623\u0633\u0627\u0633 \u0627\u0644\u0628\u064a\u0648\u0644\u0648\u062c\u064a \u0644\u0644\u0628\u062d\u0648\u062b \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644\u064a\u0629.<\/p>\n<p>\u0648\u0644\u0643\u0646\u0647\u0627 \u0644\u0627 \u062a\u0633\u0645\u062d \u0628\u062a\u062d\u062f\u064a\u062f \u0627\u0644\u0641\u0648\u0627\u0626\u062f \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0644\u062f\u0649 \u0627\u0644\u0628\u0634\u0631\u060c \u0623\u0648 \u0627\u0644\u0642\u062f\u0631\u0629 \u0639\u0644\u0649 \u0627\u0644\u062a\u062d\u0645\u0644 \u0639\u0644\u0649 \u0627\u0644\u0645\u062f\u0649 \u0627\u0644\u0637\u0648\u064a\u0644\u060c \u0623\u0648 \u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u0639\u0644\u0627\u062c\u064a \u0627\u0644\u0645\u0646\u0627\u0633\u0628.<\/p>\n<h3>\u0644\u0627 \u064a\u0645\u0643\u0646 \u0627\u0639\u062a\u0628\u0627\u0631 \u0627\u0644\u0635\u064a\u063a \u0627\u0644\u0645\u062e\u062a\u0644\u0641\u0629 \u0628\u062f\u064a\u0644\u0627\u064b \u0639\u0646 \u0628\u0639\u0636\u0647\u0627 \u0627\u0644\u0628\u0639\u0636.<\/h3>\n<p>\u0627\u0644\u0623\u0635\u0646\u0627\u0641 \u0627\u0644\u0645\u062d\u0648\u0651\u0644\u0629 \u0645\u0646 \u0627\u0644\u0628\u0628\u062a\u064a\u062f\u0627\u062a \u0648\u0646\u064f\u0638\u0645 \u0627\u0644\u062a\u0648\u0635\u064a\u0644 \u0644\u064a\u0633\u062a \u0645\u062a\u0633\u0627\u0648\u064a\u0629 \u0645\u0639 \u0627\u0644\u062a\u0631\u0643\u064a\u0628\u0629 \u0627\u0644\u0623\u0633\u0627\u0633\u064a\u0629 \u0644\u0640 B7-33.<\/p>\n<p>\u064a\u0645\u0643\u0646 \u0623\u0646 \u062a\u062d\u062f\u062b \u062a\u063a\u064a\u064a\u0631\u0627\u062a \u0643\u0628\u064a\u0631\u0629 \u0641\u064a \u0627\u0644\u062a\u0639\u0631\u0636 \u0623\u0648 \u0627\u0644\u062a\u0648\u0632\u064a\u0639 \u0644\u0644\u0645\u0648\u0627\u062f \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0644\u062f\u0647\u0648\u0646\u060c \u0648\u0627\u0644\u063a\u0637\u0627\u0621\u0627\u062a \u0630\u0627\u062a \u0627\u0644\u0625\u0641\u0631\u0627\u062c \u0627\u0644\u0645\u062d\u062f\u0648\u062f\u060c \u0648\u0627\u0644\u0623\u063a\u0637\u064a\u0629\u060c \u0648\u0627\u0644\u0630\u0631\u0627\u062a \u0627\u0644\u062f\u0642\u064a\u0642\u0629.<\/p>\n<p>\u064a\u062c\u0628 \u0623\u0646 \u062a\u0628\u0642\u0649 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0645\u0648\u0627\u062f \u0627\u0644\u0641\u0639\u0627\u0644\u0629 \u0627\u0644\u062a\u064a \u062a\u0645 \u0627\u062e\u062a\u0628\u0627\u0631\u0647\u0627 \u0628\u0627\u0644\u0641\u0639\u0644. <a href=\"https:\/\/doi.org\/10.3390\/ijms24076616\" target=\"_blank\" rel=\"noopener\">3<\/a> <a href=\"https:\/\/doi.org\/10.1021\/acsami.9b17859\" target=\"_blank\" rel=\"noopener\">9<\/a> <a href=\"https:\/\/doi.org\/10.1186\/s12929-025-01198-8\" target=\"_blank\" rel=\"noopener\">11<\/a><\/p>\n<h3>\u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u063a\u064a\u0631 \u0643\u0627\u0645\u0644\u0629<\/h3>\n<p>\u0627\u0644\u0646\u062a\u064a\u062c\u0629 \u0627\u0644\u0625\u064a\u062c\u0627\u0628\u064a\u0629 \u0641\u064a \u0646\u0645\u0648\u0630\u062c \u0627\u0644\u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u0641\u0631\u062f\u064a \u0644\u0627 \u062a\u0624\u0643\u062f \u0639\u0644\u0649 \u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u0627\u0644\u0643\u0644\u064a\u0629 \u0644\u0644\u0623\u0648\u0631\u0627\u0645.<\/p>\n<p>\u0648\u0628\u0627\u0644\u0645\u062b\u0644\u060c \u0644\u0627 \u062a\u0642\u064a\u0651\u0645 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0645\u0633\u0627\u0631 \u0627\u0644\u062d\u0645\u0644\u060c \u0643\u0645\u0627 \u0623\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0642\u0635\u064a\u0631\u0629 \u0627\u0644\u0623\u0645\u062f \u0627\u0644\u0645\u062a\u0639\u0644\u0642\u0629 \u0628\u0645\u062f\u0629 \u0628\u0642\u0627\u0621 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0644\u0627 \u062a\u0645\u0646\u0639 \u062d\u062f\u0648\u062b \u0622\u062b\u0627\u0631 \u0633\u0645\u064a\u0629 \u0639\u0644\u0649 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u062c\u0633\u0645.<\/p>\n<p>\u062a\u062a\u0637\u0644\u0628 \u0627\u0644\u0627\u0633\u062a\u0646\u062a\u0627\u062c\u0627\u062a \u0627\u0644\u0645\u0648\u062b\u0648\u0642\u0629 \u0628\u0634\u0623\u0646 \u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u0627\u0644\u0628\u0634\u0631\u064a\u0629 \u0623\u062f\u0644\u0629 \u0644\u0627 \u062a\u0648\u0641\u0631\u0647\u0627 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0627\u0644\u0645\u0630\u0643\u0648\u0631\u0629.<\/p>\n<h3>\u062a\u0639\u062a\u0628\u0631 \u062c\u0648\u062f\u0629 \u0627\u0644\u0642\u064a\u0627\u0633\u0627\u062a \u0648\u0627\u0633\u062a\u0645\u0631\u0627\u0631\u064a\u0629 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\u064a\u0634\u0643\u0644 \u0627\u0644\u062a\u0635\u0646\u064a\u0641 \u0627\u0644\u0645\u062e\u062a\u0628\u0631\u064a \u0623\u064a\u0636\u064b\u0627 \u062f\u0644\u064a\u0644\u064b\u0627 \u0639\u0644\u0649 \u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629.<\/p>\n<p>\u0644\u0627 \u062a\u0632\u0627\u0644 \u0647\u0648\u064a\u0629 \u0627\u0644\u0645\u0643\u0648\u0646 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a \u0648\u0627\u0644\u062c\u0648\u062f\u0629 \u0648\u0627\u0644\u0641\u0648\u0627\u0626\u062f \u0627\u0644\u0637\u0628\u064a\u0629 \u0645\u062c\u0627\u0644\u0627\u062a \u0645\u0646\u0641\u0635\u0644\u0629.<\/p>\n<h2>\u0623\u0643\u062b\u0631 \u0627\u0644\u0623\u0633\u0626\u0644\u0629 \u0634\u064a\u0648\u0639\u064b\u0627 \u062d\u0648\u0644 \u0627\u0644\u0628\u0628\u062a\u064a\u062f B7-33<\/h2>\n<h3>1. \u0647\u0644 \u064a\u0639\u0646\u064a B7-33 \u0645\u0627\u062f\u0629 \u0645\u062d\u062f\u062f\u0629 \u0648\u0627\u062d\u062f\u0629\u061f<\/h3>\n<p>\u0639\u0627\u062f\u0629\u064b \u0645\u0627 \u064a\u0634\u064a\u0631 \u0627\u0644\u062a\u0631\u0645\u064a\u0632 B7-33 \u0625\u0644\u0649 \u0628\u0646\u064a\u0629 \u0645\u0639\u064a\u0646\u0629 \u0645\u0639\u062f\u0644\u0629 \u0645\u0633\u062a\u0645\u062f\u0629 \u0645\u0646 \u0627\u0644\u0633\u0644\u0633\u0644\u0629 B \u0645\u0646 \u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0644\u0644\u0643\u0633\u064a\u0646\u060c \u0644\u0643\u0646 \u0627\u0644\u062a\u0641\u0627\u0635\u064a\u0644 \u0627\u0644\u062f\u0642\u064a\u0642\u0629 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0644\u0627 \u062a\u0632\u0627\u0644 \u0628\u062d\u0627\u062c\u0629 \u0625\u0644\u0649 \u0627\u0644\u062a\u062d\u0642\u0642. \u064a\u062d\u062f\u062f \u0627\u0644\u0648\u062b\u064a\u0642\u0629 \u0628\u0631\u0627\u0621\u0629 \u0627\u0644\u0627\u062e\u062a\u0631\u0627\u0639 \u0628\u064a\u0646 \u0627\u0644\u062a\u0635\u0627\u0645\u064a\u0645 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\u0627\u0644\u062f\u0645\u0648\u064a\u0629\u060c \u0644\u0643\u0646\u0647\u0627 \u0644\u0627 \u062a\u0624\u0643\u062f \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0622\u0645\u0646 \u0623\u0648 \u0627\u0644\u0641\u0639\u0627\u0644 \u0644\u062f\u0649 \u0627\u0644\u0628\u0634\u0631. <a href=\"https:\/\/doi.org\/10.1039\/c5sc04754d\" target=\"_blank\" rel=\"noopener\">1<\/a> <a href=\"https:\/\/doi.org\/10.1161\/JAHA.119.015748\" target=\"_blank\" rel=\"noopener\">5<\/a> \u062a\u062a\u0639\u0644\u0642 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0645\u0648\u0636\u062d\u0629 \u0628\u0627\u0644\u0646\u0645\u0627\u0630\u062c \u0648\u0627\u0644\u0646\u0642\u0637 \u0627\u0644\u0646\u0647\u0627\u0626\u064a\u0629 \u0627\u0644\u0645\u062d\u062f\u062f\u0629\u060c \u0648\u0644\u0630\u0644\u0643 \u0644\u0627 \u064a\u0646\u0628\u063a\u064a \u0627\u0644\u062c\u0645\u0639 \u0628\u064a\u0646\u0647\u0627 \u0641\u064a \u0625\u062d\u062f\u0649 \u0627\u0644\u0641\u0631\u0636\u064a\u0627\u062a \u0628\u0634\u0623\u0646 \u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u0627\u0644\u0623\u062c\u0647\u0632\u0629 \u0628\u0634\u0643\u0644 \u0645\u0624\u0643\u062f.<\/p>\n<h3>3. \u0647\u0644 B7-33 \u0647\u0648 \u062d\u0642\u064b\u0627 \u0628\u0631\u0648\u062a\u064a\u0646\u061f<\/h3>\n<p>\u0646\u0639\u0645. \u0627\u0644\u062a\u0635\u0645\u064a\u0645 \u0627\u0644\u0645\u0639\u062f\u0651\u0644 B7-33 \u0645\u062f\u0648\u0651\u0646 \u0648\u0647\u0648 \u0633\u0644\u0633\u0644\u0629 \u0645\u0646 \u0627\u0644\u0623\u062d\u0645\u0627\u0636 \u0627\u0644\u0623\u0645\u064a\u0646\u064a\u0629 \u062a\u062d\u062a\u0648\u064a \u0639\u0644\u0649 \u0631\u0648\u0627\u0628\u0637 \u0628\u0628\u062a\u064a\u062f\u064a\u0629. \u0625\u0646\u0647 \u0645\u062b\u064a\u0644 \u0627\u0635\u0637\u0646\u0627\u0639\u064a \u0648\u0644\u064a\u0633 \u0645\u0632\u064a\u062c\u064b\u0627 \u0645\u0646 \u0645\u0643\u0648\u0646\u0627\u062a \u063a\u064a\u0631 \u0645\u062d\u062f\u062f\u0629. <a href=\"https:\/\/patents.google.com\/patent\/US20170037106A1\/en\" target=\"_blank\" rel=\"noopener\">2<\/a> \u062a\u0624\u0643\u062f \u0648\u062c\u0648\u062f \u0627\u0644\u0647\u064a\u0643\u0644 \u0627\u0644\u062c\u0632\u064a\u0626\u064a \u0644\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u0639\u0644\u0649 \u0641\u0626\u062a\u0647 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629. \u0625\u0644\u0627 \u0623\u0646\u0647 \u0644\u0627 \u064a\u0639\u0646\u064a \u0628\u0627\u0644\u0636\u0631\u0648\u0631\u0629 \u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0623\u0648 \u0627\u0644\u0633\u0644\u0627\u0645\u0629. \u064a\u062c\u0628 \u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u062a\u0635\u0646\u064a\u0641 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a \u0648\u062d\u0627\u0644\u0629 \u0627\u0644\u062a\u062c\u0631\u0628\u0629 \u0627\u0644\u062e\u0627\u0635\u0629 \u0628\u0627\u0644\u0645\u0648\u0627\u062f \u0639\u0644\u0649 \u062d\u062f\u0629.<\/p>\n<h3>4. \u0647\u0644 \u064a\u0639\u0646\u064a \u0627\u0633\u0645 B7-33 \u0623\u0646 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0623\u0645\u064a\u0646\u064a \u064a\u062d\u062a\u0648\u064a \u0639\u0644\u0649 33 \u0623\u0645\u064a\u0646\u0648 \u0623\u0643\u0633\u064a\u062f\u061f<\/h3>\n<p>\u0644\u0627. \u062a\u062a\u0636\u0645\u0646 \u0627\u0644\u0633\u0644\u0633\u0644\u0629 \u0627\u0644\u0645\u0648\u062b\u0642\u0629 \u0627\u0644\u0623\u0631\u0642\u0627\u0645 \u0645\u0646 7 \u0625\u0644\u0649 33 \u0641\u064a \u0627\u0644\u0633\u0644\u0633\u0644\u0629 \u0627\u0644\u0623\u0645 \u0644\u0628\u0631\u0648\u062a\u064a\u0646 B\u060c \u0648\u062a\u062a\u0636\u0645\u0646 27 \u0628\u0642\u064a\u0629 \u0623\u0645\u064a\u0646\u064a\u0629. \u0648\u064a\u062a\u0645\u062b\u0644 \u0627\u0644\u0631\u0642\u0645 \u0641\u064a \u0627\u0644\u0623\u0631\u0642\u0627\u0645 \u0641\u064a \u0627\u0644\u0647\u0631\u0645\u0648\u0646 \u0627\u0644\u0623\u0633\u0627\u0633\u064a \u0648\u0627\u0644\u0637\u0648\u0644 \u0627\u0644\u0641\u0639\u0644\u064a \u0644\u0644\u0631\u0627\u0628\u0637\u0629 \u0627\u0644\u0645\u0633\u062a\u062e\u0644\u0635\u0629 \u0641\u064a \u0645\u0641\u0647\u0648\u0645\u064a\u0646 \u0645\u062e\u062a\u0644\u0641\u064a\u0646. <a href=\"https:\/\/patents.google.com\/patent\/US20170037106A1\/en\" target=\"_blank\" rel=\"noopener\">2<\/a> \u064a\u0646\u0628\u063a\u064a \u0623\u0646 \u064a\u0623\u062e\u0630 \u0627\u0644\u0648\u0635\u0641 \u0627\u0644\u0635\u062d\u064a\u062d \u0644\u0644\u062e\u0635\u0627\u0626\u0635 \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0641\u064a \u0627\u0644\u0627\u0639\u062a\u0628\u0627\u0631 \u0627\u0644\u062a\u0633\u0644\u0633\u0644 \u0648\u0627\u0644\u062a\u0639\u062f\u064a\u0644\u0627\u062a\u060c \u0628\u062f\u0644\u0627\u064b \u0645\u0646 \u0627\u0633\u062a\u062e\u0644\u0627\u0635 \u0637\u0648\u0644 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0645\u0646 \u0627\u0644\u0639\u062f\u062f \u0627\u0644\u0623\u062e\u064a\u0631 \u0641\u064a \u0627\u0633\u0645\u0647.<\/p>\n<h3>5. \u0647\u0644 B7-33 \u0647\u0648 \u0646\u0641\u0633\u0647 \u0645\u062b\u0644 \u0627\u0644\u0633\u064a\u0631\u064a\u0644\u0627\u0633\u064a\u0646\u061f<\/h3>\n<p>\u0644\u0627. \u0625\u0646 B7-33 \u0647\u0648 \u0645\u0631\u0643\u0628 \u0645\u0646\u0633\u0642 \u0645\u0646 \u0633\u0644\u0633\u0644\u0629 \u0648\u0627\u062d\u062f\u0629\u060c \u0628\u064a\u0646\u0645\u0627 \u062a\u064f\u0639\u062f \u0633\u064a\u0631\u064a\u0644\u0627\u0633\u064a\u0646 \u0634\u0643\u0644\u064b\u0627 \u0645\u062a\u062c\u062f\u062f\u064b\u0627 \u0645\u0646 \u0627\u0644\u0633\u064a\u0631\u064a\u0644\u0627\u0633\u064a\u0646-2. \u0644\u0627 \u062a\u0634\u064a\u0631 \u0627\u0644\u0639\u0646\u0627\u0635\u0631 \u0627\u0644\u0645\u0634\u062a\u0631\u0643\u0629 \u0641\u064a \u0628\u064a\u0648\u0644\u0648\u062c\u064a\u0627 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644\u0627\u062a \u0625\u0644\u0649 \u0648\u062c\u0648\u062f \u0628\u0646\u064a\u0629 \u0645\u062a\u0645\u0627\u062b\u0644\u0629 \u0623\u0648 \u0625\u0641\u0631\u0627\u0632 \u0623\u0648 \u0623\u062f\u0644\u0629 \u0633\u0631\u064a\u0631\u064a\u0629. <a href=\"https:\/\/doi.org\/10.1039\/c5sc04754d\" target=\"_blank\" rel=\"noopener\">1<\/a> \u0644\u0627 \u064a\u0645\u0643\u0646 \u0639\u0631\u0636 \u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0647\u0631\u0645\u0648\u0646 \u0627\u0644\u0623\u0645\u0648\u0645\u064a \u0643\u062f\u0631\u0627\u0633\u0627\u062a \u0633\u0631\u064a\u0631\u064a\u0629 B7-33. \u0648\u0627\u0644\u062a\u0628\u0633\u064a\u0637 \u0627\u0644\u0647\u064a\u0643\u0644\u064a \u0647\u0648 \u0627\u0644\u0623\u0633\u0627\u0633 \u0644\u0644\u0645\u0641\u0647\u0648\u0645 \u0627\u0644\u0628\u062d\u062b\u064a \u0648\u064a\u062d\u062f \u0645\u0646 \u0625\u0645\u0643\u0627\u0646\u064a\u0629 \u0646\u0642\u0644 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0628\u064a\u0646 \u0647\u0630\u0647 \u0627\u0644\u062c\u0632\u064a\u0626\u0627\u062a.<\/p>\n<h3>6. \u0645\u0627 \u0645\u0639\u0646\u0649 \u0627\u0644\u0627\u0646\u062a\u0642\u0627\u0626\u064a\u0629 \u0627\u0644\u0648\u0638\u064a\u0641\u064a\u0629 \u0644\u0640 B7-33\u061f<\/h3>\n<p>\u0641\u064a \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0645\u0630\u0643\u0648\u0631\u0629\u060c \u0643\u0627\u0646\u062a \u0627\u0644\u0627\u0646\u062a\u0642\u0627\u0626\u064a\u0629 \u0627\u0644\u0648\u0638\u064a\u0641\u064a\u0629 \u062a\u0639\u0646\u064a \u0627\u0644\u062a\u0641\u0636\u064a\u0644 \u0627\u0644\u0646\u0633\u0628\u064a \u0644\u062a\u0641\u0639\u064a\u0644 \u0631\u062f\u0648\u062f \u0625\u0634\u0627\u0631\u0627\u062a\u064a\u0629 \u0645\u0639\u064a\u0646\u0629 \u0641\u064a \u0623\u0646\u0638\u0645\u0629 \u062a\u062c\u0631\u064a\u0628\u064a\u0629 \u0645\u062d\u062f\u062f\u0629. \u0647\u0630\u0627 \u0644\u0627 \u064a\u0639\u0646\u064a \u0639\u062f\u0645 \u0648\u062c\u0648\u062f \u0623\u064a \u0622\u062b\u0627\u0631 \u0628\u064a\u0648\u0644\u0648\u062c\u064a\u0629 \u0623\u062e\u0631\u0649 \u0639\u0644\u0649 \u0627\u0644\u0625\u0637\u0644\u0627\u0642. <a href=\"https:\/\/doi.org\/10.3390\/ijms241612670\" target=\"_blank\" rel=\"noopener\">4<\/a> \u0646\u0638\u0631\u064b\u0627 \u0644\u0623\u0646 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u062a\u0639\u062a\u0645\u062f \u0639\u0644\u0649 \u0638\u0631\u0648\u0641 \u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631\u060c \u064a\u0646\u0628\u063a\u064a \u0623\u0646 \u064a\u0635\u0641 \u0627\u0644\u062a\u062d\u062f\u064a\u062f \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0645 \u0645\u0644\u0627\u062d\u0638\u062a\u0647\u0627\u060c \u0648\u0644\u064a\u0633 \u0623\u0646 \u064a\u0634\u064a\u0631 \u0625\u0644\u0649 \u062a\u0623\u062b\u064a\u0631 \u0639\u0644\u0627\u062c\u064a \u0627\u0646\u062a\u0642\u0627\u0626\u064a \u0639\u0627\u0644\u0645\u064a\u064b\u0627. \u0644\u0627 \u064a\u0636\u0645\u0646 \u0627\u0644\u062a\u0641\u0636\u064a\u0644 \u0627\u0644\u0630\u064a \u064a\u062a\u0645 \u0625\u0638\u0647\u0627\u0631\u0647 \u0641\u064a \u0627\u062e\u062a\u0628\u0627\u0631 \u0648\u0627\u062d\u062f \u0627\u0644\u062a\u0648\u0627\u0632\u0646 \u0627\u0644\u0645\u0646\u0627\u0633\u0628 \u0628\u064a\u0646 \u0627\u0644\u0641\u0648\u0627\u0626\u062f \u0648\u0627\u0644\u0645\u062e\u0627\u0637\u0631 \u0641\u064a \u062c\u0645\u064a\u0639 \u0623\u0646\u062d\u0627\u0621 \u0627\u0644\u062c\u0633\u0645.<\/p>\n<h3>7. \u0647\u0644 \u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0644\u064a\u0641\u064a\u0629 \u0627\u0644\u0628\u0634\u0631\u064a\u0629 \u062f\u0644\u064a\u0644\u064b\u0627 \u0639\u0644\u0649 \u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0639\u0644\u0627\u062c \u0644\u062f\u0649 \u0627\u0644\u0628\u0634\u0631\u061f<\/h3>\n<p>\u0644\u0627. \u0625\u0646\u0647\u0645 \u064a\u0648\u0641\u0631\u0648\u0646 \u0628\u064a\u0627\u0646\u0627\u062a \u0645\u062e\u062a\u0628\u0631\u064a\u0629 \u062a\u0645 \u0627\u0644\u062d\u0635\u0648\u0644 \u0639\u0644\u064a\u0647\u0627 \u0645\u0646 \u0645\u0648\u0627\u062f \u0645\u0646 \u0627\u0644\u0628\u0634\u0631\u060c \u0644\u0643\u0646\u0647\u0627 \u0644\u0627 \u062a\u0634\u0643\u0644 \u062f\u0644\u064a\u0644\u0627\u064b \u0639\u0644\u0649 \u0639\u0644\u0627\u062c \u0627\u0644\u0645\u0631\u0636\u0649. \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0645\u062a\u0639\u0644\u0642\u0629 \u0628\u0627\u0644\u0646\u062f\u0628\u0627\u062a \u0627\u0644\u062a\u064a \u0623\u062c\u0631\u064a\u062a \u0641\u064a \u0639\u0627\u0645 2026 \u0634\u0645\u0644\u062a \u062e\u0644\u0627\u064a\u0627 \u0648\u0645\u0648\u0627\u062f \u0644\u062a\u0632\u0648\u064a\u062f \u0627\u0644\u0628\u0628\u062a\u064a\u062f\u060c \u0648\u0644\u064a\u0633\u0647\u0627 \u0625\u062c\u0631\u0627\u0621\u064b \u0633\u0631\u064a\u0631\u064a\u0627\u064b. <a href=\"https:\/\/unipv.unifind.cineca.it\/resource\/item\/618128?language=en-US\" target=\"_blank\" rel=\"noopener\">10<\/a> \u0642\u062f \u062a\u062f\u0639\u0645 \u0647\u0630\u0647 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0646\u0638\u0631\u064a\u0651\u0629 \u0627\u0644\u0645\u064a\u0643\u0627\u0646\u064a\u0643\u064a\u0651\u0629\u060c \u0644\u0643\u0646\u0647\u0627 \u0644\u0627 \u062a\u0633\u0645\u062d \u0628\u062a\u062d\u062f\u064a\u062f \u0627\u0644\u062a\u063a\u064a\u064a\u0631\u0627\u062a \u0641\u064a \u0645\u0638\u0647\u0631 \u0627\u0644\u0646\u062f\u0648\u0628 \u0623\u0648 \u0627\u0644\u0623\u0639\u0631\u0627\u0636 \u0623\u0648 \u0627\u0644\u0642\u062f\u0631\u0629 \u0639\u0644\u0649 \u0627\u0644\u062a\u062d\u0645\u0644 \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0645\u0639\u0627\u0644\u064a\u0646. \u0644\u0627 \u064a\u064f\u0645\u0643\u0651\u0646 \u0623\u0635\u0644 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0634\u0631\u064a\u0629 \u0645\u0646 \u062a\u062d\u0648\u064a\u0644 \u0627\u0644\u0645\u062e\u062a\u0628\u0631\u0627\u062a \u0625\u0644\u0649 \u062f\u0631\u0627\u0633\u0629 \u0633\u0631\u064a\u0631\u064a\u0629.<\/p>\n<h3>8. \u0647\u0644 \u062a\u0645 \u0627\u0644\u062a\u0623\u0643\u064a\u062f \u0639\u0644\u0649 \u0623\u0646 B7-33 \u064a\u0645\u0646\u0639 \u062a\u0646\u062f\u0628 \u0627\u0644\u0628\u0634\u0631\u061f<\/h3>\n<p>\u0644\u0627. \u0644\u0627 \u062a\u0624\u0643\u062f \u0627\u0644\u0623\u062f\u0644\u0629 \u0627\u0644\u062a\u064a \u062a\u0645 \u062f\u0631\u0627\u0633\u062a\u0647\u0627 \u0639\u0643\u0633 \u0646\u0645\u0648 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0644\u062f\u0649 \u0627\u0644\u0628\u0634\u0631. \u0623\u0638\u0647\u0631\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0639\u0644\u0649 \u0627\u0644\u062d\u064a\u0648\u0627\u0646\u0627\u062a \u0622\u062b\u0627\u0631\u064b\u0627 \u0645\u0636\u0627\u062f\u0629 \u0644\u0644\u0627\u0644\u062a\u0647\u0627\u0645 \u0641\u064a \u0638\u0631\u0648\u0641 \u0645\u0639\u064a\u0646\u0629\u060c \u0644\u0643\u0646 \u0625\u0639\u0627\u062f\u0629 \u0628\u0646\u0627\u0621 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0648\u062a\u0627\u0631\u064a\u062e \u0627\u0644\u0645\u0631\u0636 \u0642\u062f \u062a\u062e\u062a\u0644\u0641 \u0628\u0634\u0643\u0644 \u0643\u0628\u064a\u0631 \u0628\u064a\u0646 \u0627\u0644\u0646\u0645\u0627\u0630\u062c \u0648\u0627\u0644\u0645\u0631\u064a\u0636\u064a\u0646. <a href=\"https:\/\/doi.org\/10.1016\/j.biopha.2023.114370\" target=\"_blank\" rel=\"noopener\">6<\/a> \u0642\u0628\u0644 \u0635\u064a\u0627\u063a\u0629 \u0627\u0644\u0627\u062f\u0639\u0627\u0621\u0627\u062a \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0629\u060c \u0643\u0627\u0646 \u0645\u0646 \u0627\u0644\u0636\u0631\u0648\u0631\u064a \u0625\u062c\u0631\u0627\u0621 \u062f\u0631\u0627\u0633\u0627\u062a \u0633\u0631\u064a\u0631\u064a\u0629. \u0642\u062f \u062a\u062e\u062a\u0644\u0641 \u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0628\u0634\u0631 \u0639\u0646 \u0627\u0644\u062a\u0635\u0644\u0628 \u0627\u0644\u0630\u064a \u062a\u0633\u0628\u0628\u0647 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0639\u0644\u0649 \u0627\u0644\u0641\u0626\u0631\u0627\u0646 \u0645\u0646 \u062d\u064a\u062b \u0645\u062f\u0629 \u0627\u0644\u0639\u0644\u0627\u062c \u0648\u0623\u0633\u0628\u0627\u0628\u0647 \u0648\u0627\u0644\u0633\u064a\u0627\u0642 \u0627\u0644\u0630\u064a \u064a\u062a\u0645 \u0641\u064a\u0647 \u0627\u0644\u0639\u0644\u0627\u062c.<\/p>\n<h3>9. \u0647\u0644 \u064a\u062b\u0628\u062a \u0627\u0646\u062e\u0641\u0627\u0636 \u0645\u0633\u062a\u0648\u0649 \u0625\u0646\u062a\u0627\u062c \u062c\u064a\u0646\u0627\u062a \u0627\u0644\u0643\u0648\u0644\u0627\u062c\u064a\u0646 \u0641\u064a \u062a\u0634\u0648\u0647 \u0627\u0644\u0646\u062f\u0628\u0629\u061f<\/h3>\n<p>\u0644\u0627. \u0625\u0646 \u0627\u0644\u062a\u0639\u0628\u064a\u0631 \u0627\u0644\u062c\u064a\u0646\u064a \u0648\u0627\u0644\u062d\u062f \u0627\u0644\u0623\u062f\u0646\u0649 \u0627\u0644\u0638\u0627\u0647\u0631 \u0644\u0644\u0646\u062f\u0628\u0629 \u0647\u0645\u0627 \u0646\u0642\u0627\u0637 \u0646\u0647\u0627\u064a\u0629 \u0645\u062e\u062a\u0644\u0641\u0629. \u0623\u0638\u0647\u0631\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0639\u0644\u0649 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0644\u064a\u0641\u0648\u0628\u0644\u0627\u0633\u062a \u0627\u0644\u0628\u0634\u0631\u064a\u0629 \u0627\u0633\u062a\u062c\u0627\u0628\u0627\u062a \u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0648\u062d\u064a\u0648\u064a\u0629\u060c \u0648\u0644\u064a\u0633 \u0627\u0646\u062d\u0633\u0627\u0631 \u0627\u0644\u0646\u062f\u0648\u0628 \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u0636\u0649. <a href=\"https:\/\/unipv.unifind.cineca.it\/resource\/item\/618128?language=en-US\" target=\"_blank\" rel=\"noopener\">10<\/a> \u062a\u062a\u0637\u0644\u0628 \u0627\u0644\u062a\u0623\u0643\u064a\u062f \u0639\u0644\u0649 \u0627\u0644\u062a\u0623\u062b\u064a\u0631 \u0627\u0644\u0647\u064a\u0643\u0644\u064a \u0623\u0648 \u0627\u0644\u062a\u062c\u0645\u064a\u0644\u064a \u0625\u062c\u0631\u0627\u0621\u0627\u062a \u0642\u064a\u0627\u0633\u0627\u062a \u0633\u0631\u064a\u0631\u064a\u0629 \u0645\u0628\u0627\u0634\u0631\u0629 \u0648\u0641\u062a\u0631\u0629 \u0631\u0635\u062f \u0645\u0646\u0627\u0633\u0628\u0629. \u0648\u064a\u062c\u0628 \u0623\u0646 \u062a\u0633\u062a\u0646\u062f \u0627\u062f\u0639\u0627\u0621\u0627\u062a \u0645\u0638\u0647\u0631 \u0627\u0644\u0646\u062f\u0628\u0629 \u0625\u0644\u0649 \u062a\u0642\u064a\u064a\u0645 \u0644\u0644\u0646\u0633\u064a\u062c\u060c \u0648\u0644\u064a\u0633 \u0641\u0642\u0637 \u0625\u0644\u0649 \u062a\u063a\u064a\u064a\u0631 \u0641\u064a \u0645\u0624\u0634\u0631 \u0627\u0644\u062c\u0632\u064a\u0626\u064a.<\/p>\n<h3>10. \u0647\u0644 B7-33 \u0623\u0643\u062b\u0631 \u0641\u0639\u0627\u0644\u064a\u0629\u064b \u0645\u0646 perindopril \u0645\u0646 \u0627\u0644\u0646\u0627\u062d\u064a\u0629 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629\u061f<\/h3>\n<p>\u0644\u0645 \u064a\u062a\u0645 \u062a\u0623\u0643\u064a\u062f \u0648\u062c\u0648\u062f \u0647\u0630\u0627 \u0627\u0644\u0645\u064a\u0632\u0629. \u0623\u062c\u0631\u064a\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0628\u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629 \u0639\u0644\u0649 \u0627\u0644\u0641\u0626\u0631\u0627\u0646 \u0648\u062a\u0645 \u062a\u062d\u0644\u064a\u0644 \u0645\u0639\u0644\u0645\u0627\u062a \u0645\u062e\u062a\u0627\u0631\u0629 \u062e\u0644\u0627\u0644 \u0641\u062a\u0631\u0629 \u062a\u062c\u0631\u064a\u0628\u064a\u0629 \u0645\u062d\u062f\u062f\u0629. \u0644\u0645 \u064a\u062a\u0645 \u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0637\u0648\u064a\u0644\u0629 \u0627\u0644\u0623\u0645\u062f \u0644\u062f\u0649 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\u062e\u0644\u0627\u064a\u0627 \u0623\u062e\u0631\u0649 \u0630\u0627\u062a \u0635\u0644\u0629. \u0644\u0627 \u062a\u0633\u0645\u062d \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0628\u062a\u062d\u062f\u064a\u062f \u0627\u0644\u0641\u0648\u0627\u0626\u062f \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0623\u0648 \u0645\u062f\u0629 \u0627\u0644\u062a\u062f\u062e\u0644 \u0623\u0648 \u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0646\u0648\u0628\u0629 \u0642\u0644\u0628\u064a\u0629. <a href=\"https:\/\/doi.org\/10.1161\/JAHA.119.015748\" target=\"_blank\" rel=\"noopener\">5<\/a> \u0648\u064a\u064f\u0639\u062f \u0627\u0644\u062a\u0639\u0628\u064a\u0631 \u0627\u0644\u0635\u062d\u064a\u062d \u0647\u0648 \u0627\u0644\u0646\u0634\u0627\u0637 \u0627\u0644\u0648\u0642\u0627\u0626\u064a \u0627\u0644\u0642\u0644\u0628\u0627\u0646\u064a \u0627\u0644\u062a\u062c\u0631\u064a\u0628\u064a\u060c \u0648\u0644\u064a\u0633 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0645\u0624\u0643\u062f. \u0648\u064a\u0634\u0643\u0644 \u0627\u0644\u0646\u0645\u0648\u0630\u062c \u0627\u0644\u0623\u0633\u0627\u0633 \u0644\u0644\u0628\u062d\u0648\u062b \u0627\u0644\u0644\u0627\u062d\u0642\u0629\u060c \u0644\u0643\u0646\u0647 \u0644\u0627 \u064a\u0634\u0643\u0644 \u062f\u0644\u064a\u0644 \u0639\u0644\u0649 \u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629 \u0641\u064a \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0641\u0648\u0631\u064a \u0644\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628\u064a\u0629.<\/p>\n<h3>12. \u0647\u0644 \u062a\u0624\u0643\u062f \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0633\u0644\u0627\u0645\u0629 B7-33 \u0623\u062b\u0646\u0627\u0621 \u0627\u0644\u062d\u0645\u0644\u061f<\/h3>\n<p>\u0644\u0627. \u0644\u0627 \u062a\u0624\u0643\u062f \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0639\u0644\u0649 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u0645\u0639\u0632\u0648\u0644\u0629 \u0641\u064a \u0646\u0645\u0648\u0630\u062c \u0645\u0631\u062a\u0628\u0637 \u0628\u062e\u0644\u0644 \u0641\u064a \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0639\u0644\u0649 \u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u0644\u062f\u0649 \u0627\u0644\u0646\u0633\u0627\u0621 \u0627\u0644\u062d\u0648\u0627\u0645\u0644 \u0623\u0648 \u0639\u0646\u062f \u0627\u0644\u0623\u062c\u0646\u0629. \u062a\u0642\u062f\u0645 \u0646\u0634\u0631\u0629 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0623\u062f\u0644\u0629 \u0645\u064a\u0643\u0627\u0646\u064a\u0643\u064a\u0629\u060c \u0648\u0644\u064a\u0633 \u0646\u062a\u0627\u0626\u062c \u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u0627\u0644\u0625\u0646\u062c\u0627\u0628\u064a\u0629. <a href=\"https:\/\/doi.org\/10.1016\/j.ejphar.2017.05.005\" target=\"_blank\" rel=\"noopener\">7<\/a> \u0644\u0630\u0627\u060c \u0644\u0627 \u064a\u0632\u0627\u0644 \u0627\u0644\u0623\u062b\u0631 \u0627\u0644\u0633\u0631\u064a\u0631\u064a \u063a\u064a\u0631 \u0645\u0624\u0643\u062f. \u0648\u064a\u062d\u062a\u0627\u062c \u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u0623\u062b\u0646\u0627\u0621 \u0627\u0644\u062d\u0645\u0644 \u0625\u0644\u0649 \u0625\u062c\u0631\u0627\u0621\u0627\u062a \u0628\u062d\u062b\u064a\u0629 \u0633\u0631\u064a\u0631\u064a\u0629 \u0648\u0645\u0633\u062a\u0642\u0644\u0629 \u0645\u0635\u0645\u0645\u0629 \u062e\u0635\u064a\u0635\u064b\u0627\u060c \u0648\u0644\u064a\u0633 \u0645\u062c\u0631\u062f \u0642\u064a\u0627\u0633\u0627\u062a \u0644\u0641\u0627\u0639\u0644\u064a\u0629 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0627\u0644\u0645\u0639\u0632\u0648\u0644\u0629.<\/p>\n<h3>13. \u0647\u0644 \u064a\u0645\u0643\u0646 \u0627\u0644\u0642\u0648\u0644 \u0625\u0646 \u062a\u0631\u0643\u064a\u0628\u0629 B7-33 \u0627\u0644\u0641\u0645\u0648\u064a\u0629 \u0627\u0644\u0639\u0627\u062f\u064a\u0629 \u0641\u0639\u0627\u0644\u0629\u061f<\/h3>\n<p>\u0644\u0627. \u0627\u0633\u062a\u062e\u062f\u0645\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0641\u0645\u0648\u064a\u0629 \u0639\u0644\u0649 \u0627\u0644\u062d\u064a\u0648\u0627\u0646\u0627\u062a \u0627\u0644\u0643\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u0645\u062a\u062e\u0635\u0635\u0629 \u0645\u0639 \u0627\u0644\u0646\u0627\u0646\u0648\u0630\u0631\u0627\u062a. \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u063a\u064a\u0631 \u0627\u0644\u0645\u062d\u0644\u0648\u0644 \u0646\u0648\u0639 \u0627\u0644\u0627\u0645\u062a\u0635\u0627\u0635 \u0648\u0627\u0644\u062a\u0639\u0631\u0636\u060c \u0648\u0644\u0630\u0644\u0643 \u0641\u0647\u0648 \u062c\u0632\u0621 \u0645\u0646 \u0627\u0644\u062a\u062f\u062e\u0644 \u0627\u0644\u0630\u064a \u062a\u0645 \u062f\u0631\u0627\u0633\u062a\u0647. <a href=\"https:\/\/doi.org\/10.1186\/s12929-025-01198-8\" target=\"_blank\" rel=\"noopener\">11<\/a> \u0625\u0646 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0644\u0627 \u062a\u0624\u0643\u062f \u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0628\u0648\u0644\u064a\u0641\u064a\u0648\u0644\u064a\u0643 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a \u0627\u0644\u0639\u0627\u062f\u064a \u0623\u0648 \u0623\u064a \u0635\u064a\u063a\u0629 \u0623\u062e\u0631\u0649. \u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0644\u0628\u0648\u0644\u064a\u0641\u0648\u0644\u064a\u0643\u064a\u062f\u0627\u062a\u060c \u062a\u0643\u0648\u0646 \u062e\u0635\u0627\u0626\u0635 \u0646\u0638\u0627\u0645 \u0627\u0644\u062a\u0648\u0632\u064a\u0639 \u0645\u0647\u0645\u0629 \u0628\u0634\u0643\u0644 \u062e\u0627\u0635\u060c \u0644\u0630\u0627 \u0644\u0627 \u064a\u0645\u0643\u0646 \u062a\u062c\u0627\u0647\u0644 \u0627\u0644\u0645\u0627\u062f\u0629 \u0627\u0644\u0645\u0633\u0646\u062f\u0629 \u0623\u062b\u0646\u0627\u0621 \u062a\u0641\u0633\u064a\u0631 \u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u062f\u0648\u0627\u0621 \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0644\u0641\u0645.<\/p>\n<h3>14. \u0647\u0644 \u0627\u0644\u0644\u064a\u062f\u0648\u064a\u062f\u0648\u0644\u064a\u062a \u0627\u0644\u062f\u0647\u0646\u064a B7-33 \u0648B7-33 \u0627\u0644\u0623\u0635\u0644\u064a \u0645\u062a\u0645\u0627\u062b\u0644\u0627\u0646\u061f<\/h3>\n<p>\u0644\u0627. \u0641\u0625\u0646 \u0627\u0644\u062f\u0647\u0648\u0646\u064a\u0629 \u062a\u064f\u063a\u064a\u0631 \u0627\u0644\u0645\u0627\u062f\u0629 \u0627\u0644\u062c\u0632\u064a\u0626\u064a\u0629 \u0648\u0642\u062f \u062a\u0624\u062b\u0631 \u0639\u0644\u0649 \u0627\u0633\u062a\u0642\u0631\u0627\u0631\u0647\u0627 \u0648\u062f\u0631\u062c\u0629 \u062a\u0639\u0631\u0636\u0647\u0627. \u0648\u0642\u062f \u062a\u0646\u0627\u0648\u0644 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\u0648\u0633\u0645\u0648\u064a\u0644\u060c \u0633. \u0643. (2016). \u0625\u0646\u0651 \u0645\u0631\u0643\u0628\u064b\u0627 \u0645\u0634\u062a\u0642\u064b\u0627 \u0645\u0646 \u0627\u0644\u0633\u0644\u0633\u0644\u0629 \u0627\u0644\u0648\u0627\u062d\u062f\u0629 \u0645\u0646 \u0647\u0631\u0645\u0648\u0646 \u0627\u0644\u0640(\u0631\u0644\u064a\u0643\u0633\u064a\u0646) \u0647\u0648 \u0639\u0627\u0645\u0644 \u062a\u062d\u0641\u064a\u0632\u064a \u0627\u0646\u062a\u0642\u0627\u0626\u064a \u0648\u0641\u0639\u0651\u0627\u0644 \u0645\u0646 \u062d\u064a\u062b \u0627\u0644\u0648\u0638\u064a\u0641\u0629 \u062a\u062c\u0627\u0647 \u0645\u0633\u062a\u0642\u0628\u0644 G protein-coupled receptor\u060c RXFP1. <em>\u0639\u0644\u0648\u0645 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0621\u060c 7<\/em>(6), 3805\u20133819. <a href=\"https:\/\/doi.org\/10.1039\/c5sc04754d\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1039\/c5sc04754d<\/a><\/li>\n<li>\u0628\u0627\u062a\u063a\u064a\u062a\u060c \u0622\u0631. \u0623. \u062f.\u060c \u062d\u0633\u064a\u0646\u060c \u0645. \u0623.\u060c \u0648\u0648\u062f\u060c \u062c. \u062f. (2017). <em>\u0633\u0644\u0633\u0644\u0627\u062a \u0627\u0644\u0628\u0628\u062a\u064a\u062f\u0627\u062a \u0627\u0644\u0645\u062d\u062f\u0651\u062b\u0629 \u0644\u0640 \u0631\u0644\u064a\u0643\u0633\u064a\u0646 B<\/em> (\u0627\u0644\u0645\u0646\u0634\u0648\u0631\u0627\u062a \u0627\u0644\u0645\u062a\u0639\u0644\u0642\u0629 \u0628\u0637\u0644\u0628\u0627\u062a \u0628\u0631\u0627\u0621\u0627\u062a \u0627\u0644\u0627\u062e\u062a\u0631\u0627\u0639 \u0641\u064a \u0627\u0644\u0648\u0644\u0627\u064a\u0627\u062a \u0627\u0644\u0645\u062a\u062d\u062f\u0629 \u0631\u0642\u0645 US20170037106A1). <a href=\"https:\/\/patents.google.com\/patent\/US20170037106A1\/en\" target=\"_blank\" rel=\"noopener\">https:\/\/patents.google.com\/patent\/US20170037106A1\/en<\/a><\/li>\n<li>\u0628\u0631\u0627\u0641\u064a\u0646\u060c \u0628\u064a\u060c \u0648\u0627\u0646\u063a\u060c \u0633\u064a\u060c \u0647\u0646\u062f\u0644\u064a\u060c \u062a\u064a. \u0646. \u062c\u064a\u060c \u0648\u0648\u060c \u0647. \u0633\u060c \u0633\u0627\u0645\u0648\u064a\u0644\u060c \u0633\u064a. \u0625\u0633\u060c \u0628\u0627\u062a\u063a\u064a\u062a\u060c \u0622\u0631. \u0623. \u062f.\u060c \u0648\u0647\u0648\u0633\u0627\u064a\u0646\u060c \u0645. \u0623. (2023). \u0625\u0646\u062a\u0627\u062c \u0645\u0634\u062a\u0642 \u0648\u0627\u062d\u062f \u0645\u0646 \u0627\u0644\u0633\u0644\u0633\u0644\u0629 B \u0645\u0646 \u0627\u0644\u0644\u064a\u0648\u0633\u064a\u0646 \u0645\u0639 \u0645\u0631\u0643\u0628\u0627\u062a \u062f\u0647\u0646\u064a\u0629\u060c \u064a\u0638\u0647\u0631 \u062a\u062d\u0633\u0646\u064b\u0627 \u0641\u064a \u0627\u0633\u062a\u0642\u0631\u0627\u0631 \u0627\u0644\u0633\u064a\u0631\u0648\u0645 \u0641\u064a \u0627\u0644\u0645\u062e\u062a\u0628\u0631 \u062f\u0648\u0646 \u062a\u063a\u064a\u064a\u0631 \u0627\u0644\u0646\u0634\u0627\u0637. <em>\u0627\u0644\u0645\u062c\u0644\u0629 \u0627\u0644\u062f\u0648\u0644\u064a\u0629 \u0644\u0644\u0639\u0644\u0648\u0645 \u0627\u0644\u062c\u0632\u064a\u0626\u064a\u0629\u060c 24<\/em>(7)\u060c \u0627\u0644\u0645\u0627\u062f\u0629 6616. <a href=\"https:\/\/doi.org\/10.3390\/ijms24076616\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.3390\/ijms24076616<\/a><\/li>\n<li>\u0647\u0627\u0646\u0644\u064a\u060c \u062a\u064a. \u0646. \u062c\u064a\u060c \u0628\u0631\u064a\u0641\u064a\u0646\u060c \u0628\u064a\u060c \u062a\u0627\u064a\u0644\u0647\u0627\u064a\u062f\u0632\u060c \u062c\u060c \u0648\u0648\u060c \u0647.\u060c \u0628\u0627\u062a\u063a\u064a\u062a\u060c \u0622\u0631. \u0623. \u062f.\u060c \u0648\u0647\u0648\u0633\u0627\u064a\u0646\u060c \u0645\u0627. \u0623. (2023). \u062a\u0637\u0648\u0631\u0627\u062a \u0625\u0636\u0627\u0641\u064a\u0629 \u0646\u062d\u0648 \u062a\u062d\u0636\u064a\u0631 \u0646\u0628\u0627\u062a\u064a \u0636\u0639\u064a\u0641 \u0627\u0644\u0646\u0634\u0627\u0637 \u0625\u0644\u0649 \u062d\u062f \u0623\u062f\u0646\u0649 \u0645\u0646 \u0631\u0644\u064a\u0643\u0633\u064a\u0646-2 \u0627\u0644\u0628\u0634\u0631\u064a. <em>\u0627\u0644\u0645\u062c\u0644\u0629 \u0627\u0644\u062f\u0648\u0644\u064a\u0629 \u0644\u0644\u0639\u0644\u0648\u0645 \u0627\u0644\u062c\u0632\u064a\u0626\u064a\u0629\u060c 24<\/em>(16)\u060c \u0627\u0644\u0645\u0627\u062f\u0629 12670. <a href=\"https:\/\/doi.org\/10.3390\/ijms241612670\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.3390\/ijms241612670<\/a><\/li>\n<li>\u062f\u064a\u0648\u0627\u0631\u0627\u0643\u0648\u0646\u062f\u0627\u060c \u062a.\u060c \u0645\u0627\u0648\u0631\u0648\u060c \u0623. \u062c\u064a\u060c \u063a\u0648\u0632\u0645\u0627\u0646\u060c \u062c.\u060c \u0647\u0648\u0641\u0633\u0628\u064a\u0627\u0646\u060c \u0633.\u060c \u0643\u0627\u064a\u064a\u0646\u060c \u0633.\u060c \u062f\u0627\u0633\u060c \u0623.\u060c \u0628\u0631\u064a\u0641\u064a\u0646\u060c \u0628\u064a.\u060c \u062d\u0633\u0627\u064a\u0646\u060c \u0645. \u0623.\u060c \u0648\u0633\u0644\u0648\u0645\u060c \u0641. \u0646. (2020). B7-33\u060c \u0648\u0647\u0648 \u0645\u062b\u0628\u0637 \u0645\u062d\u062f\u062f \u0644\u0646\u0634\u0627\u0637 \u0645\u0633\u062a\u0642\u0628\u0644\u0627\u062a \u0627\u0644\u0640 relaxin 1\u060c \u064a\u062d\u062f\u0651 \u0645\u0646 \u0625\u0639\u0627\u062f\u0629 \u062a\u0634\u0643\u064a\u0644 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0633\u0644\u0628\u064a\u0629 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0625\u0646\u062a\u0647\u0627\u0621 \u0642\u0635\u0648\u0631 \u0627\u0644\u0642\u0644\u0628 \u0644\u062f\u0649 \u0627\u0644\u0641\u0626\u0631\u0627\u0646. <em>\u0645\u062c\u0644\u0629 \u062c\u0645\u0639\u064a\u0629 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629\u060c 9<\/em>(8)\u060c e015748. <a href=\"https:\/\/doi.org\/10.1161\/JAHA.119.015748\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1161\/JAHA.119.015748<\/a><\/li>\n<li>\u0623\u0644\u0627\u0645\u060c \u0641.\u060c \u063a\u0627\u0633\u0627\u0631\u064a\u060c \u062a\u064a. \u0623.\u060c \u0643\u0627\u0645\u0628-\u0647\u0627\u0631\u0628\u0631\u060c \u0628\u064a. \u0643.\u060c \u0644\u0648\u060c \u0625\u064a.\u060c \u0623\u0648\u0627\u0641\u060c \u0623.\u060c \u0641\u064a\u0631\u0646\u0633\u060c \u062f.\u060c \u0633\u0628\u064a\u0632\u064a\u0648\u060c \u0622\u064a.\u060c \u062c\u064a\u0641\u0631\u064a\u0632\u060c \u0623. \u0645.\u060c \u0641\u064a\u0631\u064a\u0646\u0628\u060c \u0628\u064a.\u060c \u0648\u064a\u062f\u0648\u0628\u060c \u0631. \u0625\u064a.\u060c \u0628\u0627\u062a\u063a\u064a\u062a\u060c \u0622\u0631. \u0623. \u062f.\u060c \u062d\u0633\u064a\u0646\u060c \u0645. \u0623.\u060c \u0648\u0633\u0627\u0645\u0648\u064a\u0644\u060c \u0633. \u0643. (2023). \u0627\u0644\u0645\u0627\u062f\u0629 \u0627\u0644\u062a\u0645\u0627\u062b\u0644\u064a\u0629 \u0644\u0644\u0631\u0644\u0627\u0643\u0633\u064a\u0646 \u0630\u0627\u062a \u0627\u0644\u0633\u0644\u0633\u0644\u0629 \u0627\u0644\u0648\u0627\u062d\u062f\u0629\u060c B7-33\u060c \u062a\u062d\u0627\u0641\u0638 \u0639\u0644\u0649 \u062a\u0623\u062b\u064a\u0631\u0627\u062a \u0627\u0644\u0631\u0644\u0627\u0643\u0633\u064a\u0646 \u0627\u0644\u0648\u0642\u0627\u0626\u064a\u0629 \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0648\u062a\u062d\u062f \u0645\u0646 \u062a\u0635\u0644\u0628 \u0627\u0644\u0635\u0645\u0627\u0645 \u0627\u0644\u0623\u0628\u0647\u0631 \u0628\u0634\u0643\u0644 \u0623\u0633\u0631\u0639 \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u0628\u0631\u064a\u0646\u064a\u062f\u0648\u0628\u0631\u064a\u0644 \u0641\u064a \u0646\u0645\u0648\u0630\u062c \u062a\u062c\u0631\u064a\u0628\u064a \u0644\u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628 \u0627\u0644\u062e\u0644\u0642\u064a. <em>\u0627\u0644\u0637\u0628 \u0627\u0644\u0628\u064a\u0637\u0631\u064a \u0648\u0627\u0644\u0637\u0628 \u0627\u0644\u062f\u0648\u0627\u0626\u064a\u060c 160<\/em>, 114370. <a href=\"https:\/\/doi.org\/10.1016\/j.biopha.2023.114370\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1016\/j.biopha.2023.114370<\/a><\/li>\n<li>\u0645\u0627\u0631\u0634\u0627\u0644\u060c S. A.\u060c \u0623\u0648\u0633\u0648\u0644\u064a\u0641\u0627\u0646\u060c \u0643.\u060c \u0646\u063a\u060c H. H.\u060c \u0628\u0627\u062a\u063a\u064a\u062a\u060c \u0622\u0631. \u0623. \u062f.\u060c \u0628\u0627\u0631\u064a\u0631\u064a\u060c \u0644. \u062c.\u060c \u062d\u0633\u0627\u064a\u0646\u060c \u0645. \u0623.\u060c \u0648\u0644\u064a\u0648\u060c C. H. (2017). B7-33 \u064a\u0639\u064a\u062f \u0625\u0646\u062a\u0627\u062c \u0627\u0644\u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u0648\u0627\u0635\u0644\u0627\u062d\u064a\u0629 \u0644\u0644\u0631\u0626\u0629 \u0644\u0640 human relaxin-2 (serelaxin). <em>\u0645\u062c\u0644\u0629 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a\u0629\u060c \u0627\u0644\u0639\u062f\u062f 807<\/em>, 190\u2013197. <a href=\"https:\/\/doi.org\/10.1016\/j.ejphar.2017.05.005\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1016\/j.ejphar.2017.05.005<\/a><\/li>\n<li>\u0628\u0648\u064a\u064a\u0627\u0646\u060c S., \u0634\u0646\u060c M., \u062a\u0634\u0627\u0644\u0648\u0627\u0631\u062a\u0645\u0627\u0646\u060c S., \u062a\u0627\u0646\u060c A. Y., \u0647\u0648\u060c G., \u062d\u0633\u0627\u064a\u0646\u060c M. A., \u0648\u064a\u062f\u0648\u0628\u060c R. E. \u0648 \u0633\u064a\u0645\u0648\u0646\u060c C. S. (2021). \u062a\u0642\u064a\u064a\u0645 \u062a\u0635\u0644\u0628 \u0627\u0644\u0643\u0644\u0649 \u0648\u0627\u0644\u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0644\u0644\u0635\u0644\u0627\u0628\u0629 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0645\u0646\u0635\u0629 \u0625\u0646\u062a\u0627\u062c\u064a\u0629 \u062b\u0627\u0646\u064a\u0629 \u0645\u062a\u0648\u0627\u0641\u0642\u0629 \u0645\u0639 \u0627\u0644\u062a\u0644\u0648\u064a\u0646 \u062c\u062f\u064a\u062f\u0629. <em>\u0645\u062c\u0644\u0629 FASEB\u060c \u0627\u0644\u0639\u062f\u062f 35<\/em>(5)\u060c e21595. <a href=\"https:\/\/doi.org\/10.1096\/fj.202002053RRR\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1096\/fj.202002053RRR<\/a><\/li>\n<li>\u0648\u064a\u0644\u062a\u0634\u060c \u0646. \u062c\u064a\u060c \u0648\u0645\u0648\u0643\u0631\u064a\u060c \u0633.\u060c \u0648\u0647\u0648\u0633\u0627\u064a\u064a\u0646\u060c \u0645. \u0623\u060c \u0648\u0628\u0631\u064a\u0641\u064a\u0646\u060c \u0628.\u060c \u0648\u0648\u0631\u0643\u0645\u0627\u064a\u0633\u062a\u064a\u0631\u060c \u062c. \u0623\u060c \u0648\u0648\u062f\u060c \u062c. \u062f.\u060c \u0648\u0628\u0627\u062a\u063a\u064a\u062a\u060c \u0622\u0631. \u0623. \u062f.\u060c \u0648\u0641\u064a\u0646\u0643\u0644\u0631\u060c \u062f. \u0623.\u060c \u0648\u062a\u064a\u0633\u064a\u0646\u060c \u0647. (2019). \u0648\u062c\u0648\u062f \u0637\u0628\u0642\u0627\u062a \u0631\u0642\u064a\u0642\u0629 \u0645\u0646 \u0645\u0627\u062f\u0629 B7-33\u060c \u0645\u0645\u0627\u062b\u0644\u0629 \u0644\u0628\u0628\u062a\u064a\u062f \u0627\u0644\u0640(relaxin)\u060c \u064a\u0642\u0644\u0644 \u0645\u0646 \u0627\u0644\u062a\u0643\u0644\u0633 \u0641\u064a \u0627\u0644\u063a\u0634\u0627\u0621. <em>ACS Applied Materials &amp; Interfaces\u060c 11<\/em>(49), 45511\u201345519. <a href=\"https:\/\/doi.org\/10.1021\/acsami.9b17859\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1021\/acsami.9b17859<\/a><\/li>\n<li>\u062a\u0627\u0645\u0628\u064a\u0631\u064a\u0644\u0644\u0648\u060c \u0645.\u060c \u0628\u064a\u0646\u062f\u064a\u062a\u064a\u060c \u0644.\u060c \u062a\u0634\u064a\u062e\u064a\u0647\u060c \u0625.\u060c \u0628\u064a\u0633\u0627\u0646\u064a\u060c \u0633.\u060c \u063a\u064a\u0646\u062a\u0627\u060c \u0625.\u060c \u0643\u0648\u0646\u062a\u064a\u060c \u0628.\u060c \u0633\u064a\u0643\u0627\u062a\u0627\u0631\u0644\u064a\u060c \u062c.\u060c \u0648\u062f\u0648\u0631\u0627\u062a\u064a\u060c \u0622\u0631. (2026). B7-33 \u064a\u0646\u0638\u0645 \u0627\u0644\u0625\u0634\u0627\u0631\u0627\u062a \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 \u0641\u064a \u062e\u0644\u0627\u064a\u0627 \u0623\u0644\u064a\u0627\u0641 \u0627\u0644\u0646\u062f\u0628\u0629 \u0627\u0644\u0645\u062a\u0636\u062e\u0645\u0629: \u062f\u0631\u0627\u0633\u0629 \u0641\u064a \u0627\u0644\u0645\u062e\u062a\u0628\u0631 \u062a\u062f\u0639\u0645 \u0627\u0633\u062a\u0631\u0627\u062a\u064a\u062c\u064a\u0629 \u0639\u0644\u0627\u062c\u064a\u0629 \u062c\u062f\u064a\u062f\u0629. <em>\u0645\u062c\u0644\u0629 \u0639\u0644\u0648\u0645 \u0648\u062a\u0643\u0646\u0648\u0644\u0648\u062c\u064a\u0627 \u062a\u0648\u0635\u064a\u0644 \u0627\u0644\u0645\u062e\u062f\u0631\u0627\u062a\u060c \u0627\u0644\u0639\u062f\u062f 121<\/em>, \u0627\u0644\u0645\u0627\u062f\u0629 108327. <a href=\"https:\/\/unipv.unifind.cineca.it\/resource\/item\/618128?language=en-US\" target=\"_blank\" rel=\"noopener\">https:\/\/unipv.unifind.cineca.it\/resource\/item\/618128?language=en-US<\/a><\/li>\n<li>\u0633\u0648\u0645\u0627\u0646\u0627\u062f\u064a\u0631-\u0644\u064a\u0631\u0627\u060c \u062f. \u0641. \u0648\u0646\u060c \u0648\u064a\u060c \u0633.\u060c \u0648\u0627\u0646\u063a\u060c \u0633.\u060c \u0648\u0644\u064a\u060c \u064a.\u060c \u0641\u064a\u0631\u0646\u0633\u060c \u062f.\u060c \u0633\u0644\u064a\u0645\u0648\u0641\u0644\u0627\u060c \u0625.\u060c \u0633\u064a\u0644\u0648\u0645\u0648\u0644\u064a\u0627\u060c \u0633.\u060c \u062d\u0633\u0627\u064a\u0646\u060c \u0645. \u0623.\u060c \u0633\u0627\u0645\u0648\u064a\u0644\u060c \u0633. \u0643.\u060c \u0648\u0643\u0631\u0627\u062a\u0634\u0627\u064a\u0628\u0631\u062c\u064a\u060c \u0623. (2025). \u0627\u0633\u062a\u064a\u0639\u0627\u0628 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0646\u0627\u0639\u0629 \u0644\u0644\u0646\u0627\u0646\u0648\u0628\u0648\u062a\u064a\u0643\u0644\u0627\u062a \u0627\u0644\u062c\u0644\u064a\u0633\u064a\u0646\u0627\u062a \u0627\u0644\u0645\u0634\u062a\u0642\u0629 \u0645\u0646 \u0627\u0644\u0628\u0628\u062a\u064a\u062f\u0627\u062a \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0644\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u0627\u062a\u060c \u0645\u0645\u0627 \u064a\u062a\u064a\u062d \u0644\u0647\u0627 \u0627\u0644\u0627\u0633\u062a\u0645\u0631\u0627\u0631 \u0641\u064a \u0627\u0644\u0646\u0634\u0627\u0637 \u0648\u062a\u0646\u0627\u0648\u0644\u0647 \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0644\u0641\u0645. <em>\u0645\u062c\u0644\u0629 \u0627\u0644\u0639\u0644\u0648\u0645 \u0627\u0644\u0637\u0628\u064a\u0629 \u0627\u0644\u062d\u064a\u0648\u064a\u0629\u060c \u0627\u0644\u0639\u062f\u062f 32<\/em>(1), 104. <a href=\"https:\/\/doi.org\/10.1186\/s12929-025-01198-8\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1186\/s12929-025-01198-8<\/a><\/li>\n<li>\u0632\u0627\u063a\u060c \u0644.\u060c \u062f\u0648\u0646\u063a\u060c \u0625\u0643\u0633.\u060c \u0634\u064a\u060c \u0643.\u060c \u064a\u0627\u0648\u060c \u0625\u0643\u0633.\u060c \u062a\u0634\u0646\u060c \u0643.\u060c \u0648\u0627\u0646\u060c \u062c.\u060c \u0648\u0627\u0646\u063a\u060c \u0641.\u060c \u0646\u064a\u060c \u0633.\u060c \u0644\u064a\u060c \u064a.\u060c \u0648\u0627\u0646\u063a\u060c \u0645.\u060c \u0634\u064a\u0646\u063a\u060c \u064a.\u060c \u0644\u064a\u0648\u060c \u062c.\u060c \u062c\u064a\u060c \u062a\u064a.\u060c \u0648\u062a\u0634\u064a\u0646\u060c \u0632. (2025). \u0627\u0644\u0641\u064a\u062a\u0627\u0645\u064a\u0646\u0627\u062a \u0627\u0644\u0635\u063a\u064a\u0631\u0629 \u0630\u0627\u062a \u0627\u0644\u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u0645\u0632\u062f\u0648\u062c\u0629 \u062a\u0645\u0646\u0639\u0627\u0646 \u0641\u064a \u0646\u0641\u0633 \u0627\u0644\u0648\u0642\u062a \u062a\u0644\u064a\u0641 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0638\u0647\u0627\u0631\u064a\u0629 \u0648\u062a\u0646\u0645\u064a\u0629 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629\u060c \u0645\u0645\u0627 \u064a\u062d\u062f \u0645\u0646 \u062a\u0642\u062f\u0645 \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u0642\u0646\u0627\u0629 \u0627\u0644\u0635\u0641\u0631\u0627\u0648\u064a\u0629. <em>\u0645\u062c\u0644\u0629 \u0646\u0627\u0646\u0648\u0648\u0628\u064a\u0648\u062a\u0643\u0646\u0627\u0648\u062a\u064a\u0643\u060c \u0627\u0644\u0639\u062f\u062f 23<\/em>(1), 781. <a href=\"https:\/\/doi.org\/10.1186\/s12951-025-03833-w\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1186\/s12951-025-03833-w<\/a><\/li>\n<\/ol>","protected":false},"excerpt":{"rendered":"<p>B7-33 \u0647\u0648 \u0628\u0631\u0648\u062a\u064a\u0646 \u0639\u0636\u0648\u064a \u062a\u0645 \u062a\u0637\u0648\u064a\u0631\u0647 \u0627\u0633\u062a\u0646\u0627\u062f\u064b\u0627 \u0625\u0644\u0649 \u0633\u0644\u0633\u0644\u0629 B \u0645\u0646 \u0628\u0631\u0648\u062a\u064a\u0646 RELAXIN-2 \u0627\u0644\u0628\u0634\u0631\u064a. \u062a\u0645 \u0625\u0646\u0634\u0627\u0624\u0647 \u0645\u0646 \u0623\u062c\u0644 \u062f\u0631\u0627\u0633\u0629 \u0645\u0627 \u0625\u0630\u0627 \u0643\u0627\u0646 \u0627\u0644\u0628\u062f\u064a\u0644 \u0627\u0644\u0645\u0643\u0648\u0646 \u0645\u0646 \u0633\u0644\u0633\u0644\u0629 \u0648\u0627\u062d\u062f\u0629 \u0627\u0644\u0628\u0633\u064a\u0637\u0629 \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u0639\u064a\u062f \u0625\u0646\u062a\u0627\u062c \u0627\u0644\u062a\u0623\u062b\u064a\u0631\u0627\u062a \u0627\u0644\u0625\u0634\u0627\u0631\u0627\u062a\u064a\u0629 \u0627\u0644\u0645\u062e\u062a\u0627\u0631\u0629 \u0644\u0644\u0645\u0627\u062f\u0629 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0627\u0644\u0647\u0631\u0645\u0648\u0646\u064a\u0629 \u0627\u0644\u0623\u0643\u0628\u0631\u2026<\/p>","protected":false},"author":7910,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[305,293],"tags":[],"class_list":["post-56785","post","type-post","status-publish","format-standard","hentry","category-materialy-edukacyjne","category-blog","beh-no-thumb"],"_links":{"self":[{"href":"https:\/\/bioevidencehub.com\/ar\/wp-json\/wp\/v2\/posts\/56785","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bioevidencehub.com\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bioevidencehub.com\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bioevidencehub.com\/ar\/wp-json\/wp\/v2\/users\/7910"}],"replies":[{"embeddable":true,"href":"https:\/\/bioevidencehub.com\/ar\/wp-json\/wp\/v2\/comments?post=56785"}],"version-history":[{"count":2,"href":"https:\/\/bioevidencehub.com\/ar\/wp-json\/wp\/v2\/posts\/56785\/revisions"}],"predecessor-version":[{"id":56789,"href":"https:\/\/bioevidencehub.com\/ar\/wp-json\/wp\/v2\/posts\/56785\/revisions\/56789"}],"wp:attachment":[{"href":"https:\/\/bioevidencehub.com\/ar\/wp-json\/wp\/v2\/media?parent=56785"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bioevidencehub.com\/ar\/wp-json\/wp\/v2\/categories?post=56785"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bioevidencehub.com\/ar\/wp-json\/wp\/v2\/tags?post=56785"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}