{"id":46058,"date":"2026-04-24T17:02:39","date_gmt":"2026-04-24T15:02:39","guid":{"rendered":"https:\/\/semaxpolska.com\/?p=46058"},"modified":"2026-07-12T12:02:08","modified_gmt":"2026-07-12T10:02:08","slug":"%e9%8a%85%e3%83%9a%e3%83%97%e3%83%81%e3%83%89ghk-cu%e3%81%ae%e5%89%af%e4%bd%9c%e7%94%a8","status":"publish","type":"post","link":"https:\/\/bioevidencehub.com\/ja\/skutki-uboczne-peptydu-miedzi-ghk-cu\/","title":{"rendered":"\u79d1\u5b66\u7684\u7814\u7a76\u306b\u304a\u3051\u308b\u9285\u30da\u30d7\u30c1\u30c9\uff08GHK-Cu\uff09\u306e\u526f\u4f5c\u7528"},"content":{"rendered":"

\u79d1\u5b66\u7684\u7814\u7a76\u3067\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u9285\u30da\u30d7\u30c1\u30c9(GHK-Cu)\u306e\u526f\u4f5c\u7528\u306f\u3001\u305f\u3044\u3066\u3044\u306e\u5834\u5408\u3054\u304f\u308f\u305a\u304b\u3067\u3001\u8efd\u3044\u5c40\u6240\u53cd\u5fdc\u306b\u9650\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u76ae\u819a\u306e\u8001\u5316\u3084\u5275\u50b7\u6cbb\u7652\u306e\u3088\u3046\u306a\u5916\u7528\u5264\u3092\u4f7f\u3063\u305f\u30d2\u30c8\u306e\u7814\u7a76\u3067\u306f\u3001\u9285\u30da\u30d7\u30c1\u30c9\u306f\u901a\u5e38\u3088\u304f\u8010\u3048\u3089\u308c\u307e\u3059\u3002\u53c2\u52a0\u8005\u306e\u306a\u304b\u306b\u306f\u3001\u5857\u5e03\u90e8\u4f4d\u306e\u308f\u305a\u304b\u306a\u76ae\u819a\u523a\u6fc0\u3001\u308f\u305a\u304b\u306a\u767a\u8d64\u3001\u4e00\u904e\u6027\u306e\u904e\u654f\u75c7\u3092\u5831\u544a\u3057\u305f\u8005\u3082\u3044\u308b(Pickart & Margolina, 2018; Reddy et al., 2012)\u3002\u3053\u308c\u3089\u306e\u75c7\u72b6\u306f\u901a\u5e38\u3001\u6301\u7d9a\u6642\u9593\u304c\u77ed\u304f\u3001\u4f7f\u7528\u3092\u7d9a\u3051\u3066\u3082\u6301\u7d9a\u3057\u306a\u3044\u3002\u52d5\u7269\u8a66\u9a13\u3084\u5b9f\u9a13\u5ba4\u3067\u306e\u5b9f\u9a13\u3067\u306f\u3001\u6a19\u6e96\u7684\u306a\u8a66\u9a13\u7528\u91cf\u3067\u306f\u5168\u8eab\u6bd2\u6027\u306e\u4e00\u8cab\u3057\u305f\u5fb4\u5019\u306f\u89b3\u5bdf\u3055\u308c\u306a\u304b\u3063\u305f\u3002\u5168\u4f53\u3068\u3057\u3066\u3001\u9285\u30da\u30d7\u30c1\u30c9\u306f\u4ed6\u306e\u751f\u7269\u5b66\u7684\u306b\u6d3b\u6027\u306a\u30da\u30d7\u30c1\u30c9\u3068\u6bd4\u8f03\u3057\u3066\u3001\u597d\u307e\u3057\u3044\u5b89\u5168\u6027\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u6301\u3064\u5316\u5408\u7269\u3068\u3057\u3066\u3057\u3070\u3057\u3070\u8a18\u8ff0\u3055\u308c\u308b\u3002.<\/p>\n

\u30e1\u30ab\u30cb\u30ba\u30e0\u304b\u3089\u898b\u308b\u3068\u3001\u526f\u4f5c\u7528\u306e\u767a\u751f\u7387\u304c\u4f4e\u3044\u306e\u306f\u3001\u3053\u306e\u30da\u30d7\u30c1\u30c9\u304c\u30d2\u30c8\u306e\u4f53\u5185\u306b\u81ea\u7136\u306b\u5b58\u5728\u3059\u308b\u304b\u3089\u304b\u3082\u3057\u308c\u306a\u3044\u3002\u8840\u6f3f\u3084\u553e\u6db2\u306e\u3088\u3046\u306a\u4f53\u6db2\u4e2d\u306b\u3082\u3001\u7d44\u7e54\u4e2d\u306b\u3082\u5b58\u5728\u3057\u3001\u514d\u75ab\u53cd\u5fdc\u3084\u6bd2\u6027\u306e\u30ea\u30b9\u30af\u3092\u6e1b\u3089\u3057\u3066\u3044\u307e\u3059\u3002\u52a0\u3048\u3066\u3001\u9285\u30da\u30d7\u30c1\u30c9\u306f\u9285\u3068\u5f37\u304f\u7d50\u5408\u3059\u308b\u305f\u3081\u3001\u9285\u306e\u904b\u642c\u3092\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u8a98\u767a\u3059\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u904a\u96e2\u9285\u306e\u84c4\u7a4d\u3092\u6e1b\u3089\u3059\u3053\u3068\u304c\u3067\u304d\u308b\u3002\u3057\u304b\u3057\u3001\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u30c7\u30fc\u30bf\u306e\u307b\u3068\u3093\u3069\u306f\u5c40\u6240\u7684\u306a\u4f7f\u7528\u306b\u3088\u308b\u3082\u306e\u3067\u3042\u308a\u3001\u5168\u8eab\u7684\u306a\u66b4\u9732\u306b\u3088\u308b\u3082\u306e\u3067\u306f\u306a\u3044\u3053\u3068\u306b\u6ce8\u610f\u3057\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002\u3053\u306e\u7814\u7a76\u3067\u4f7f\u308f\u308c\u305f\u9285\u30da\u30d7\u30c1\u30c9\u306f\u3001SemaxPolska\u306e\u3088\u3046\u306a\u30b5\u30d7\u30e9\u30a4\u30e4\u30fc\u304b\u3089\u5165\u624b\u53ef\u80fd\u3067\u3042\u308b\u3002\u4eca\u56de\u306e\u7814\u7a76\u3067\u91cd\u7be4\u306a\u526f\u4f5c\u7528\u304c\u306a\u304b\u3063\u305f\u304b\u3089\u3068\u3044\u3063\u3066\u3001\u7279\u306b\u9ad8\u7528\u91cf\u3084\u5168\u8eab\u7684\u306a\u4f7f\u7528\u306b\u304a\u3044\u3066\u3001\u9577\u671f\u7684\u306a\u5b89\u5168\u6027\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3068\u3044\u3046\u3053\u3068\u306b\u306f\u306a\u3089\u306a\u3044\u3002.<\/p>\n

\u9285\u30da\u30d7\u30c1\u30c9(GHK-Cu)\u306f\u30d2\u30c8\u81e8\u5e8a\u8a66\u9a13\u3067\u5b89\u5168\u3060\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u304b\uff1f<\/strong><\/h2>\n

\u9285\u30da\u30d7\u30c1\u30c9\u306f\u4e00\u822c\u7684\u306b\u3001\u5229\u7528\u53ef\u80fd\u306a\u81e8\u5e8a\u7814\u7a76\u304a\u3088\u3073\u7f8e\u5bb9\u7814\u7a76\u306b\u57fa\u3065\u3044\u3066\u3001\u7279\u306b\u5c40\u6240\u7684\u306b\u9069\u7528\u3055\u308c\u305f\u5834\u5408\u3001\u5b89\u5168\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u69d8\u3005\u306a\u6295\u4e0e\u65b9\u6cd5\u306b\u304a\u3051\u308b\u5305\u62ec\u7684\u306a\u5b89\u5168\u6027\u30c7\u30fc\u30bf\u306f\u307e\u3060\u9650\u3089\u308c\u3066\u3044\u308b\u3053\u3068\u306b\u7559\u610f\u3059\u3079\u304d\u3067\u3042\u308b\u3002\u76ae\u819a\u306e\u8001\u5316\u3068\u5275\u50b7\u6cbb\u7652\u3092\u542b\u3080\u30d2\u30c8\u3067\u306e\u5bfe\u7167\u7814\u7a76\u3067\u306f\u3001\u826f\u597d\u306a\u5fcd\u5bb9\u6027\u3068\u91cd\u7be4\u306a\u526f\u4f5c\u7528\u304c\u306a\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b\u3002\u6570\u9031\u9593\u306b\u308f\u305f\u308b\u5b9a\u671f\u7684\u306a\u4f7f\u7528\u3092\u542b\u3080\u3053\u308c\u3089\u306e\u7814\u7a76\u3067\u306f\u3001\u76ae\u819a\u30d1\u30e9\u30e1\u30fc\u30bf\u30fc\u306e\u6539\u5584\u3082\u540c\u6642\u306b\u793a\u3055\u308c\u3066\u304a\u308a\uff08Pickart & Margolina, 2018; Mulder et al.<\/p>\n

\u3057\u304b\u3057\u3001\u307b\u3068\u3093\u3069\u306e\u30c7\u30fc\u30bf\u306f\u5316\u7ca7\u54c1\u3084\u5916\u7528\u5264\u306b\u3088\u308b\u3082\u306e\u3067\u3042\u308b\u3002\u9577\u671f\u9593\u306e\u4f7f\u7528\u3084\u5168\u8eab\u6295\u4e0e\u3001\u3055\u307e\u3056\u307e\u306a\u96c6\u56e3\u3067\u306e\u52b9\u679c\u3092\u8a55\u4fa1\u3059\u308b\u3001\u5927\u898f\u6a21\u3067\u30c7\u30b6\u30a4\u30f3\u3055\u308c\u305f\u81e8\u5e8a\u7814\u7a76\u306f\u4e0d\u8db3\u3057\u3066\u3044\u307e\u3059\u3002\u56fd\u306b\u3088\u3063\u3066\u306f\u3001\u9285\u30da\u30d7\u30c1\u30c9\u306f\u533b\u85ac\u54c1\u3067\u306f\u306a\u304f\u5316\u7ca7\u54c1\u6210\u5206\u3068\u3057\u3066\u5206\u985e\u3055\u308c\u3066\u3044\u307e\u3059\u3002.<\/p>\n

\u751f\u7269\u5b66\u7684\u89b3\u70b9\u304b\u3089\u306f\u3001\u4f53\u5185\u3067\u306e\u81ea\u7136\u306a\u5b58\u5728\u3068\u4fee\u5fa9\u904e\u7a0b\u3078\u306e\u95a2\u4e0e\u304c\u3001\u305d\u306e\u5b89\u5168\u6027\u3092\u88cf\u4ed8\u3051\u3066\u3044\u308b\u3002\u3057\u304b\u3057\u3001\u3053\u308c\u306f\u3055\u3089\u306a\u308b\u81e8\u5e8a\u8a66\u9a13\u306e\u5fc5\u8981\u6027\u306b\u53d6\u3063\u3066\u4ee3\u308f\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3053\u306e\u7814\u7a76\u3067\u4f7f\u308f\u308c\u305f\u9285\u30da\u30d7\u30c1\u30c9\u306f\u3001\u30bb\u30de\u30c3\u30af\u30b9\u30dd\u30eb\u30b9\u30ab\u306a\u3069\u306e\u30b5\u30d7\u30e9\u30a4\u30e4\u30fc\u304b\u3089\u5165\u624b\u53ef\u80fd\u3067\u3059\u3002\u73fe\u5728\u306e\u30c7\u30fc\u30bf\u3067\u306f\u3001\u5c40\u6240\u7684\u306a\u4f7f\u7528\u3067\u306e\u5b89\u5168\u6027\u306f\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u9577\u671f\u7684\u3042\u308b\u3044\u306f\u5168\u8eab\u7684\u306a\u4f7f\u7528\u3067\u306e\u5b8c\u5168\u306a\u81e8\u5e8a\u7684\u5b89\u5168\u6027\u306f\u652f\u6301\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002.<\/p>\n

\u9285\u30da\u30d7\u30c1\u30c9(GHK-Cu)\u306b\u95a2\u3059\u308b\u79d1\u5b66\u6587\u732e\u4e0a\u306e\u6bd2\u6027\u5b66\u7684\u30c7\u30fc\u30bf\u306f\u3042\u308a\u307e\u3059\u304b\uff1f<\/strong><\/h2>\n

\u9285\u30da\u30d7\u30c1\u30c9\u306b\u95a2\u3059\u308b\u6bd2\u6027\u5b66\u7684\u30c7\u30fc\u30bf\u306f\u3001\u5b9f\u9a13\u5ba4\uff08in vitro\uff09\u304a\u3088\u3073\u52d5\u7269\uff08in vivo\uff09\u306e\u4e21\u65b9\u306e\u7814\u7a76\u306b\u304a\u3044\u3066\u3001\u6bd2\u6027\u304c\u4f4e\u3044\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u7814\u7a76\u306b\u3088\u308c\u3070\u3001\u9285\u30da\u30d7\u30c1\u30c9\u306f\u751f\u7269\u5b66\u7684\u30b7\u30b9\u30c6\u30e0\u3067\u898b\u3089\u308c\u308b\u306e\u3068\u540c\u3058\u3088\u3046\u306a\u6fc3\u5ea6\u3067\u306f\u3001\u7d30\u80de\u306e\u751f\u5b58\u7387\u306b\u60aa\u5f71\u97ff\u3092\u4e0e\u3048\u306a\u3044\u3002\u3044\u304f\u3064\u304b\u306e\u7814\u7a76\u3067\u306f\u3001\u9285\u30da\u30d7\u30c1\u30c9\u304c\u7d30\u80de\u306e\u4fee\u5fa9\u3092\u4fc3\u9032\u3057\u3001\u6297\u9178\u5316\u6d3b\u6027\u3092\u9ad8\u3081\u308b\u3053\u3068\u3055\u3048\u793a\u3055\u308c\u3066\u3044\u307e\u3059(Gruchlik et al., 2012)\u3002\u5275\u50b7\u6cbb\u7652\u3001\u708e\u75c7\u3001\u7d44\u7e54\u518d\u751f\u306b\u7126\u70b9\u3092\u5f53\u3066\u305f\u52d5\u7269\u5b9f\u9a13\u3067\u306f\u3001\u5178\u578b\u7684\u306a\u8a66\u9a13\u7528\u91cf\u306b\u304a\u3044\u3066\u3001\u81d3\u5668\u969c\u5bb3\u3084\u91cd\u5927\u306a\u5168\u8eab\u3078\u306e\u5f71\u97ff\u306f\u793a\u3055\u308c\u3066\u3044\u306a\u3044\uff08Ma et al.\u30012020\uff1bPark et al.\u30012016\uff09\u3002.<\/p>\n

\u76ae\u819a\u306e\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u8ffd\u52a0\u7814\u7a76\u3067\u306f\u3001\u7e70\u308a\u8fd4\u3057\u5916\u7528\u3057\u3066\u3082\u523a\u6fc0\u6027\u304c\u4f4e\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b\uff08Lima & Moraes, 2018\uff09\u3002\u8fc5\u901f\u306a\u4ee3\u8b1d\u3068\u4f53\u5916\u3078\u306e\u6392\u51fa\u3082\u91cd\u8981\u306a\u8981\u7d20\u3067\u3042\u308a\u3001\u84c4\u7a4d\u306e\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3059\u308b\u3002.<\/p>\n

\u30e1\u30ab\u30cb\u30ba\u30e0\u7684\u306b\u306f\u3001\u9285\u30da\u30d7\u30c1\u30c9\u306f\u751f\u7269\u5b66\u7684\u30d7\u30ed\u30bb\u30b9\u306e\u8abf\u6574\u5f79\u3068\u3057\u3066\u50cd\u304d\u3001\u907a\u4f1d\u5b50\u767a\u73fe\u3084\u9178\u5316\u30d0\u30e9\u30f3\u30b9\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3002\u3053\u308c\u304c\u6bd2\u6027\u306e\u4f4e\u3055\u306b\u3064\u306a\u304c\u3063\u3066\u3044\u308b\u3002\u3057\u304b\u3057\u3001\u6bd2\u6027\u5b66\u7684\u30c7\u30fc\u30bf\u306e\u307b\u3068\u3093\u3069\u306f\u3001\u524d\u81e8\u5e8a\u8a66\u9a13\u3084\u77ed\u671f\u9593\u306e\u7814\u7a76\u306b\u3088\u308b\u3082\u306e\u3067\u3042\u308b\u3053\u3068\u3092\u5f37\u8abf\u3057\u3066\u304a\u304d\u305f\u3044\u3002\u7814\u7a76\u306b\u4f7f\u7528\u3055\u308c\u305f\u9285\u30da\u30d7\u30c1\u30c9\u306f\u3001SemaxPolska\u306e\u3088\u3046\u306a\u30b5\u30d7\u30e9\u30a4\u30e4\u30fc\u304b\u3089\u5165\u624b\u53ef\u80fd\u3067\u3042\u308b\u3002\u73fe\u5728\u306e\u30c7\u30fc\u30bf\u306f\u3001\u3059\u3079\u3066\u306e\u5857\u5e03\u65b9\u6cd5\u3084\u30d2\u30c8\u3078\u306e\u9577\u671f\u4f7f\u7528\u306b\u304a\u3051\u308b\u5b89\u5168\u306a\u66b4\u9732\u30ec\u30d9\u30eb\u3092\u6c7a\u5b9a\u3059\u308b\u306b\u306f\u4e0d\u5341\u5206\u3067\u3042\u308b\u3002.<\/p>\n

\u9285\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u5d29\u308c\u308b\u5371\u967a\u6027\u306f\u7814\u7a76\u3067\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u304b\uff1f<\/strong><\/h2>\n

\u9285\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u5d29\u308c\u308b\u3068\u3044\u3046\u6f5c\u5728\u7684\u306a\u30ea\u30b9\u30af\u306f\u7814\u7a76\u3067\u3082\u8003\u616e\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u7814\u7a76\u3067\u7528\u3044\u3089\u308c\u305f\u6a19\u6e96\u30ec\u30d9\u30eb\u3067\u306f\u3001\u5b9f\u9a13\u7d50\u679c\u304b\u3089\u306f\u5f37\u304f\u652f\u6301\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u9285\u30da\u30d7\u30c1\u30c9(GHK-Cu)\u306f\u9285\u3068\u5f37\u304f\u7d50\u5408\u3057\u3001\u5236\u5fa1\u3055\u308c\u305f\u30ad\u30e3\u30ea\u30a2\u3068\u3057\u3066\u50cd\u304d\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u904a\u96e2\u306e\u9285\u30a4\u30aa\u30f3\u306e\u30ec\u30d9\u30eb\u3092\u4e0a\u3052\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u5b89\u5168\u306a\u5f62\u3067\u9285\u3092\u904b\u3073\u307e\u3059\u3002\u904a\u96e2\u9285\u306f\u6709\u5bb3\u306a\u9178\u5316\u53cd\u5fdc\u3092\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308b\u304c\u3001\u9285\u30da\u30d7\u30c1\u30c9\u306f\u9285\u3092\u5b89\u5b9a\u3057\u305f\u5236\u5fa1\u3055\u308c\u305f\u72b6\u614b\u306b\u4fdd\u3064\u3053\u3068\u3067\u3001\u3053\u306e\u30ea\u30b9\u30af\u3092\u8efd\u6e1b\u3059\u308b\uff08Pickart\u3089\u30012015\u5e74\uff09\u3002.<\/p>\n

\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306b\u95a2\u3059\u308b\u7814\u7a76\u3067\u306f\u3001\u9285\u30da\u30d7\u30c1\u30c9\u306f\u6297\u9178\u5316\u30b7\u30b9\u30c6\u30e0\u3092\u30b5\u30dd\u30fc\u30c8\u3057\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u304b\u3089\u306e\u4fdd\u8b77\u306b\u95a2 \u9023\u3059\u308b\u907a\u4f1d\u5b50\u3092\u5236\u5fa1\u3059\u308b\u3053\u3068\u3067\u3001\u7d30\u80de\u306e\u30c0\u30e1\u30fc\u30b8\u3092\u8efd\u6e1b\u3059\u308b\u53ef\u80fd\u6027\u3055\u3048\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b(Ma et al., 2020)\u3002\u3057\u304b\u3057\u3001\u975e\u5e38\u306b\u9ad8\u7528\u91cf\u3067\u3042\u3063\u305f\u308a\u3001\u7570\u5e38\u306a\u84c4\u7a4d\u3067\u3042\u3063\u305f\u308a\u3059\u308b\u3068\u3001\u4f53\u5185\u306e\u9285\u306e\u81ea\u7136\u306a\u30d0\u30e9\u30f3\u30b9\u3001\u7279\u306b\u91d1\u5c5e\u306b\u654f\u611f\u306a \u4f53\u7cfb\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u3044\u3046\u7406\u8ad6\u7684\u306a\u61f8\u5ff5\u304c\u3042\u308a\u307e\u3059\u3002.<\/p>\n

\u73fe\u5728\u307e\u3067\u306e\u3068\u3053\u308d\u3001\u6a19\u6e96\u7684\u306a\u5b9f\u9a13\u3084\u7f8e\u5bb9\u306e\u6761\u4ef6\u4e0b\u3067\u3001\u9285\u30da\u30d7\u30c1\u30c9\u3092\u4f7f\u3063\u305f\u304b\u3089\u3068\u3044\u3063\u3066\u3001\u9285\u304c\u904e\u5270\u306b\u306a\u3063\u305f\u308a\u3001\u91cd\u5927\u306a\u30a2\u30f3\u30d0\u30e9\u30f3\u30b9\u304c\u751f\u3058\u305f\u308a\u3059\u308b\u3088\u3046\u306a\u660e\u78ba\u306a\u4f8b\u306f\u898b\u3064\u304b\u3063\u3066\u3044\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u307b\u3068\u3093\u3069\u306e\u7814\u7a76\u306f\u7ba1\u7406\u3055\u308c\u305f\u6761\u4ef6\u4e0b\u3067\u3001\u6bd4\u8f03\u7684\u4f4e\u7528\u91cf\u3001\u5c40\u6240\u6295\u4e0e\u3067\u884c\u306a\u308f\u308c\u3066\u3044\u308b\u305f\u3081\u3001\u7d50\u679c\u306e\u4e00\u822c\u5316\u306b\u306f\u9650\u754c\u304c\u3042\u308b\u3053\u3068\u3092\u5ff5\u982d\u306b\u7f6e\u304f\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002.<\/p>\n

\u30e1\u30ab\u30cb\u30ba\u30e0\u7684\u306b\u306f\u3001\u9285\u30da\u30d7\u30c1\u30c9\u306f\u8abf\u7bc0\u3055\u308c\u305f\u8f38\u9001\u30b7\u30b9\u30c6\u30e0\u3068\u3057\u3066\u4f5c\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u9285\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u4fdd\u3064\u306e\u306b \u5f79\u7acb\u3063\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3053\u306e\u30d0\u30e9\u30f3\u30b9\u306f\u6295\u4e0e\u91cf\u3001\u6295\u4e0e\u65b9\u6cd5\u3001\u751f\u7269\u5b66\u7684\u80cc\u666f\u306a\u3069\u306e\u8981\u56e0\u306b\u5de6\u53f3\u3055\u308c\u307e\u3059\u3002\u3053\u306e\u7814\u7a76\u3067\u4f7f\u308f\u308c\u305f\u9285\u30da\u30d7\u30c1\u30c9\u306f\u3001SemaxPolska\u306e\u3088\u3046\u306a\u30b5\u30d7\u30e9\u30a4\u30e4\u30fc\u304b\u3089\u5165\u624b\u53ef\u80fd\u3067\u3059\u3002\u9285\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u5d29\u308c\u308b\u5371\u967a\u6027\u306b\u3064\u3044\u3066\u306e\u660e\u78ba\u306a\u8a3c\u62e0\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u9577\u671f\u3042\u308b\u3044\u306f\u9ad8\u7528\u91cf\u306e\u5168\u8eab\u4f7f\u7528\u306b\u3088\u308b\u5f71\u97ff\u306f\u5b8c\u5168\u306b\u306f\u7406\u89e3\u3055\u308c\u3066\u304a\u3089\u305a\u3001\u3055\u3089\u306a\u308b\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3059\u3002.<\/p>\n

 <\/p>\n

\u53c2\u8003\u6587\u732e<\/h4>\n
    \n
  • Pickart, L., & Margolina, A. (2018).\u65b0\u3057\u3044\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u306b\u7167\u3089\u3057\u305fGHK-Cu\u30da\u30d7\u30c1\u30c9\u306e\u518d\u751f\u30fb\u4fdd\u8b77\u4f5c\u7528\u3002. \u5206\u5b50\u79d1\u5b66\u56fd\u969b\u30b8\u30e3\u30fc\u30ca\u30eb, 19<\/em>(7), 1987.<\/span><\/li>\n
  • Reddy, B. Y., Jow, T., & Hantash, B. M. (2012).\u76ae\u819a\u79d1\u5b66\u306b\u304a\u3051\u308b\u751f\u7406\u6d3b\u6027\u30aa\u30ea\u30b4\u30da\u30d7\u30c1\u30c9\uff1a\u30d1\u30fc\u30c8I. \u5b9f\u9a13\u76ae\u819a\u79d1\u5b66, 21<\/em>(8), 563\u2013568.<\/span><\/li>\n
  • Mulder, G. D., Patt, L. M., Sanders, L., Rosenstock, J., Altman, M. I., Hanley, M. E., & Duncan, G. W. (1994).\u30b0\u30ea\u30b7\u30eb-L-\u30d2\u30b9\u30c1\u30b8\u30eb-L-\u30ea\u30b8\u30f3\u9285\u306b\u3088\u308b\u5c40\u6240\u6cbb\u7642\u306b\u3088\u308b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306e\u6f70\u760d\u6cbb\u7652\u306e\u4fc3\u9032\u3002. \u50b7\u306e\u4fee\u5fa9\u3068\u518d\u751f, 2<\/em>(4), 259\u2013269.<\/span><\/li>\n
  • Gruchlik, A., Jurzak, M., Chodurek, E., & Dzierzewicz, Z. (2012).\u6b63\u5e38\u30d2\u30c8\u76ae\u819a\u7dda\u7dad\u82bd\u7d30\u80de\u306b\u304a\u3051\u308bTNF-\u03b1\u4f9d\u5b58\u6027IL-6\u5206\u6ccc\u306b\u5bfe\u3059\u308bGly-Gly-His\u3001Gly-His-Lys\u304a\u3088\u3073\u305d\u308c\u3089\u306e\u9285\u8907\u5408\u4f53\u306e\u52b9\u679c\u3002. \u30dd\u30fc\u30e9\u30f3\u30c9\u85ac\u5264\u5b66\u4f1a\u8a8c69\u53f7<\/em>(6), 1303\u20131309.<\/span><\/li>\n
  • Ma, W., Li, M., Ma, H., Li, W., Liu, L., Yin, Y., Zhou, X., & Hou, G. (2020).GHK-Cu\u306e\u6297\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u304a\u3088\u3073\u6297\u708e\u75c7\u7d4c\u8def\u3092\u4ecb\u3057\u305f\u30d6\u30ec\u30aa\u30de\u30a4\u30b7\u30f3\u8a98\u767a\u80ba\u7dda\u7dad\u75c7\u306b\u304a\u3051\u308b\u4fdd\u8b77\u52b9\u679c\u3002. \u30e9\u30a4\u30d5\u30b5\u30a4\u30a8\u30f3\u30b9, 241<\/em>, 117139.<\/span><\/li>\n
  • Park, J. R., Lee, H., Kim, S. I., & Yang, S. R. (2016).\u30c8\u30ea\u30da\u30d7\u30c1\u30c9GHK-Cu\u8907\u5408\u4f53\u306f\u3001\u30de\u30a6\u30b9\u306b\u304a\u3051\u308b\u30ea\u30dd\u591a\u7cd6\u8a98\u767a\u6025\u6027\u80ba\u969c\u5bb3\u3092\u6539\u5584\u3059\u308b\u3002. \u30aa\u30f3\u30b3\u30bf\u30fc\u30b2\u30c3\u30c8, 7<\/em>(37), 58405\u201358417.<\/span><\/li>\n
  • Lima, T. N., & Pedriali Moraes, C. A. (2018).Bioactive peptides: Applications and relevance for cosmeceuticals. \u5316\u7ca7\u54c1, 5<\/em>(2), 21.<\/span><\/li>\n
  • Pickart, L., Vasquez-Soltero, J. M., & Margolina, A. (2015).GHK-Cu\u306f\u3001\u9285\u3092\u5236\u5fa1\u3057\u3001\u591a\u6570\u306e\u6297\u9178\u5316\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u4fee\u98fe\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u76ae\u819a\u306e\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u9632\u3050\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002. \u5316\u7ca7\u54c1, 2<\/em>(3), 236\u2013247.<\/span><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"

    \u79d1\u5b66\u7684\u7814\u7a76\u306b\u304a\u3044\u3066\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u9285\u30da\u30d7\u30c1\u30c9\uff08GHK-Cu\uff09\u306e\u526f\u4f5c\u7528\u306f\u3001\u901a\u5e38\u3054\u304f\u8efd\u5fae\u3067\u3042\u308a\u3001\u307b\u3068\u3093\u3069\u306e\u5834\u5408\u3001\u8efd\u5ea6\u306e\u5c40\u6240\u53cd\u5fdc\u306b\u3068\u3069\u307e\u3063\u3066\u3044\u307e\u3059\u3002\u30d2\u30c8\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u3067\u306f\u3001\u2026\u2026<\/p>","protected":false},"author":7908,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[93],"tags":[],"class_list":["post-46058","post","type-post","status-publish","format-standard","hentry","category-kategoria-ghk-cu","beh-no-thumb"],"_links":{"self":[{"href":"https:\/\/bioevidencehub.com\/ja\/wp-json\/wp\/v2\/posts\/46058","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bioevidencehub.com\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bioevidencehub.com\/ja\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bioevidencehub.com\/ja\/wp-json\/wp\/v2\/users\/7908"}],"replies":[{"embeddable":true,"href":"https:\/\/bioevidencehub.com\/ja\/wp-json\/wp\/v2\/comments?post=46058"}],"version-history":[{"count":0,"href":"https:\/\/bioevidencehub.com\/ja\/wp-json\/wp\/v2\/posts\/46058\/revisions"}],"wp:attachment":[{"href":"https:\/\/bioevidencehub.com\/ja\/wp-json\/wp\/v2\/media?parent=46058"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bioevidencehub.com\/ja\/wp-json\/wp\/v2\/categories?post=46058"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bioevidencehub.com\/ja\/wp-json\/wp\/v2\/tags?post=46058"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}