{"id":56551,"date":"2026-09-29T13:21:52","date_gmt":"2026-09-29T11:21:52","guid":{"rendered":"https:\/\/bioevidencehub.com\/?p=56551"},"modified":"2026-09-24T16:11:34","modified_gmt":"2026-09-24T14:11:34","slug":"%ed%8e%a9%ed%83%80%ec%9d%b4%eb%93%9c-%eb%b6%84%eb%a6%ac","status":"publish","type":"post","link":"https:\/\/bioevidencehub.com\/ko\/sprzeganie-peptydow\/","title":{"rendered":"\ud3a9\ud0c0\uc774\ub4dc \ud63c\ud569: \ucd09\ub9e4\uc81c, \ubcf4\ud638\uae30 \ubc0f \ubd80\uc791\uc6a9 \ubc18\uc751"},"content":{"rendered":"

\ud3a9\ud0c0\uc774\ub4dc \uacb0\ud569\uc740 \ubcf4\ub974\ucf54\uc0b0 \uadf8\ub8f9\uc744 \ud3ec\ud568\ud558\ub294 \uc131\ubd84\uacfc \uc544\ubbfc \uadf8\ub8f9\uc744 \ud3ec\ud568\ud558\ub294 \uc131\ubd84 \uc0ac\uc774\uc758 \uacb0\ud569\uc744 \uc0dd\uc131\ud558\ub294 \ud654\ud559\uc801 \uacfc\uc815\uc785\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ubc18\uc751\uc758 \uacb0\uacfc\ub85c \uc544\ubbf8\ub4dc \uacb0\ud569\uc774 \ud615\uc131\ub429\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uacb0\ud569\uc740 \ud3a9\ud0c0\uc774\ub4dc \ud569\uc131\uc744 \ud1b5\ud574 \uc544\ubbf8\ub178\uc0b0 \uc794\uae30\ub97c \uacb0\ud569\uc2dc\ud0a4\ub294 \uc5ed\ud560\uc744 \uc218\ud589\ud558\uba70, \uc774\ub97c \ud3a9\ud0c0\uc774\ub4dc \uad6c\uc870\uccb4\ub77c\uace0 \ud558\ub294 \uac83\uc73c\ub85c \uc815\uc758\ub429\ub2c8\ub2e4.<\/p>\n

\ubc18\uc751\uc131 \uc131\ubd84\ub4e4\uc740 \ub2e8\uc77c \uc544\ubbf8\ub178\uc0b0\uc774 \ub420 \ud544\uc694\ub294 \uc5c6\uc2b5\ub2c8\ub2e4. \uacb0\ud569 \ubc18\uc751\uc740 \ud558\ub098 \uc774\uc0c1\uc758 \uc544\ubbf8\ub178\uc0b0\uc744 \ub2e4\ub978 \uc544\ubbf8\ub178\uc0b0\uacfc \uacb0\ud569\uc2dc\ud0a4\uac70\ub098, \uc131\uc7a5\ud558\ub294 \ub2e8\ubc31\uc9c8 \uc0ac\uc2ac\uc5d0 \ub2e4\uc74c \uc544\ubbf8\ub178\uc0b0\uc744 \ucd94\uac00\uc2dc\ud0a4\uac70\ub098, \uc774\uc804\uc5d0\ub294 \ubcc4\ub3c4\ub85c \ud569\uc131\ub41c \ub354 \ud070 \ub2e8\ubc31\uc9c8 \uc870\uac01\ub4e4\uc744 \uacb0\ud569\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uac89\uc73c\ub85c \ubcf4\uba74 \ub2e8\ubc31\uc9c8\uc758 \uacb0\ud569\uc740 \uac04\ub2e8\ud55c \uc791\uc5c5\ucc98\ub7fc \ubcf4\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub2e8 \ud558\ub098\uc758 \uc544\ubbf8\ub178\uc0b0\uc744 \ub2e4\ub978 \uc544\ubbf8\ub178\uc0b0\uacfc \uacb0\ud569\ud558\uae30\ub9cc \ud558\uba74 \ub429\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \ud654\ud559\uc801 \uad00\uc810\uc5d0\uc11c \ubcf4\uba74 \uc544\ubbfc \uacb0\ud569\uc758 \uc0dd\uc131\uc740 \uc804\uccb4 \ubaa9\uc801\uc758 \uc77c\ubd80\uc5d0 \ubd88\uacfc\ud569\ub2c8\ub2e4.<\/p>\n

\uc5f0\uacb0\uc740 \uc62c\ubc14\ub978 \uc704\uce58\uc5d0\uc11c \uc801\uc808\ud55c \uc2a4\ud14c\ub808\uc624\uc2dc\uc2a4 \uad6c\uc131\ud558\uc5d0 \uc774\ub8e8\uc5b4\uc838\uc57c \ud558\uba70, \ub2e4\ub978 \ubc18\uc751\uc131 \uae30\ub2a5 \uadf8\ub8f9\ub4e4\uc740 \uc801\uc808\ud788 \uc81c\uc5b4\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4. \ubc18\uc751\uc740 \uc678\uad00\uc0c1\uc73c\ub85c\ub294 \uc131\uacf5\uc801\uc73c\ub85c \uc9c4\ud589\ub420 \uc218 \uc788\uace0, \ucd9c\ucc98 \ubb3c\uc9c8\uc758 \ub300\ubd80\ubd84 \ub610\ub294 \uc804\uccb4\ub97c \uc18c\ubaa8\ud560 \uc218 \uc788\uc9c0\ub9cc, \uadf8\ub7fc\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0 \ucd5c\uc885 \ud3a9\ud2f0\ub4dc\uc640 \ub2e4\ub978 \uad6c\uc870\ubb3c\ub4e4\uc758 \ubd88\ud544\uc694\ud55c \ud63c\ud569\ubb3c\uc744 \uc0dd\uc131\ud558\uac8c \ud560 \uc218 \uc788\ub2e4.<\/p>\n

\uadf8\ub807\uae30 \ub54c\ubb38\uc5d0 \ubc18\uc751\uc758 \uc885\ub8cc\uc640 \uc81c\ud488\uc758 \uc815\ud655\ud55c \uc0dd\uc131\uc740 \uac19\uc740 \uac83\uc744 \uc758\ubbf8\ud558\uc9c0 \uc54a\ub294\ub2e4.<\/p>\n

\ub2e4\uc591\ud55c \uacb0\ud569 \uc2dc\uc2a4\ud15c, \uae30\ub2a5 \uadf8\ub8f9 \ubcf4\ud638 \uc804\ub7b5 \ubc0f stereochemic \uacb0\uacfc\ub4e4\uc744 \ube44\uad50\ud55c \uc5f0\uad6c\ub4e4\uc740 \ud569\uc131\ub41c \ub2e8\ubc31\uc9c8\uc758 \uc885\ub958\uc5d0 \uad00\uacc4\uc5c6\uc774 \ud56d\uc0c1 \uac00\uc7a5 \ud6a8\uacfc\uc801\uc778 \uacb0\ud569 \ucd09\ub9e4\uac00 \uc874\uc7ac\ud558\uc9c0 \uc54a\ub294 \uc774\uc720\ub97c \ubcf4\uc5ec\uc900\ub2e4.<\/p>\n

\uacfc\ud559\uc801 \uad00\uc810\uc5d0\uc11c \ubcfc \ub54c \ub354 \uc720\uc6a9\ud55c \uc9c8\ubb38\uc740 \ub2e4\uc74c\uacfc \uac19\uc2b5\ub2c8\ub2e4:<\/p>\n

\u201e\uc5b4\ub5a4 \uacb0\ud569\uc81c\ub294 \uac00\uc7a5 \uc88b\uc2b5\ub2c8\uae4c?\u201d<\/p>\n

\ub354 \ub098\uc740 \uc9c8\ubb38\uc740 \ub2e4\uc74c\uacfc \uac19\uc2b5\ub2c8\ub2e4:<\/p>\n

\u201e\uc5b4\ub5a4 \uc811\uadfc \ubc29\uc2dd\uc774 \ud2b9\uc815 \ubd84\uc790 \uc870\uac74\uc5d0\uc11c \uc801\uc808\ud55c \ud398\ube0d\ud2b8\ub97c \uc801\uc808\ud55c \ubcc0\ud658, stereochemical integrity \uc720\uc9c0 \ubc0f \uc624\uc5fc\ubb3c\uc9c8\uc758 \uc801\uc808\ud55c \uc81c\uc5b4\ub97c \ud1b5\ud574 \uc5bb\uc744 \uc218 \uc788\ub294\uac00?\u201d<\/p>\n

\uc774 \ucc28\uc774\ub294 \ub2e8\ubc31\uc9c8 \uacb0\ud569 \ud654\ud559\uc744 \uc774\ud574\ud558\ub294 \ub370 \uc788\uc5b4 \ub9e4\uc6b0 \uc911\uc694\ud569\ub2c8\ub2e4.<\/p>\n

\ud3a9\ud2f0\ub4dc \uacb0\ud569\uc774\ub780 \ubb34\uc5c7\uc744 \uc758\ubbf8\ud558\ub294\uac00?<\/h2>\n

\uc5f0\uacb0\uc740 \uc0c8\ub85c\uc6b4 \uacb0\ud569\uc744 \uc0dd\uc131\ud558\uc5ec \ub450 \uc131\ubd84\uc744 \uc5f0\uacb0\ud569\ub2c8\ub2e4.<\/h3>\n

\ud3a9\ud2f0\ub4dc \uad6c\uc870\ub97c \ud615\uc131\ud558\ub294 \uc77c\ubc18\uc801\uc778 \ubc18\uc751\uc5d0\uc11c \ud558\ub098\uc758 \uc544\ubbf8\ub178\uc0b0 \uc794\uae30\uc640 \uacb0\ud569\ub41c \uce74\ubcf4\ub2d0 \uadf8\ub8f9\uc740 \ub2e4\ub978 \uc544\ubbf8\ub178\uc0b0 \uc794\uae30\uc640 \uacb0\ud569\ub429\ub2c8\ub2e4.<\/p>\n

\uc0dd\uc131\ub418\ub294 \uacb0\ud569\uc740 \ud654\ud559\uc801\uc73c\ub85c \uc544\ubbfc \uacb0\ud569\uc785\ub2c8\ub2e4.<\/p>\n

\ub9cc\uc57d \uc774\ub7ec\ud55c \uacb0\ud569\uc774 \ud3a9\ud2f0\ub4dc \uc0ac\uc2ac \ub0b4\uc758 \ub2e4\ub978 \uc544\ubbf8\ub178\uc0b0\ub4e4\uc744 \uc5f0\uacb0\ud55c\ub2e4\uba74, \uc774\ub97c \uc77c\ubc18\uc801\uc73c\ub85c \ud3a9\ud2f0\ub4dc \uacb0\ud569\uc774\ub77c\uace0 \ubd80\ub985\ub2c8\ub2e4.<\/p>\n

\ubc18\uc751\uc131 \uc131\ubd84\ub4e4\uc758 \uc815\ud655\ud55c \ubb3c\ub9ac\uc801 \ubc30\uce58\ub294 \ud569\uc131 \uc804\ub7b5\uc5d0 \ub530\ub77c \ub2ec\ub77c\uc9d1\ub2c8\ub2e4.<\/p>\n

\ud3a9\ud0c0\uc774\ub4dc \ud569\uc131 \ub2e8\uacc4\uc5d0\uc11c \uc548\uc815\uc0c1\ud0dc\uc5d0\uc11c \ubc1c\uacac\ub418\ub294 \uc544\ubbf8\ub178\uae30\ub294 \uc77c\ubc18\uc801\uc73c\ub85c \uc810\ud1a0\uc5d0 \uacb0\ud569\ub41c \uc131\uc7a5\ud558\ub294 \ud3a9\ud0c0\uc774\ub4dc \uc0ac\uc2ac\uc5d0 \uc18d\ud558\uc9c0\ub9cc, \uce74\ubcf4\ub2d0 \uadf8\ub8f9\uc744 \ud3ec\ud568\ud558\ub294 \uc131\ubd84\uc740 \ub3c4\uc785\ub41c \uc548\uc815\ud654\ub41c \uc544\ubbf8\ub178\uc0b0\uc5d0\uc11c \uc720\ub798\ud569\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \uc6a9\uc561 \ub0b4\uc5d0\uc11c \uc218\ud589\ub418\ub294 \ud569\uc131\uc5d0\uc11c\ub294 \ub450 \uc131\ubd84 \ubaa8\ub450 \uc561\uc0c1 \uc0c1\ud0dc\uc5d0 \uc788\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ubd80\ubd84\ub4e4\uc744 \uacb0\ud569\ud558\ub294 \uacbd\uc6b0, \ub2e8\uc77c \uc544\ubbf8\ub178\uc0b0 \uc794\ub958\ubb3c\uc744 \ud558\ub098\uc529 \ucd94\uac00\ud558\ub294 \ub300\uc2e0 \ub354 \ud070 \ubcf4\ud638\ub41c \ub2e8\ubc31\uc9c8 \uc138\uadf8\uba3c\ud2b8\ub97c \uacb0\ud569\ud569\ub2c8\ub2e4.<\/p>\n

\ub2e4\uc591\ud55c \uc804\ub7b5\uc740 \ubc18\uc751\uc758 \uc218\ud589 \ubc29\uc2dd, \ubb3c\uc9c8\uc758 \ubd84\ub9ac \ubc0f \uc815\uc81c \ubc29\uc2dd\uc744 \ubcc0\ud654\uc2dc\ud0b5\ub2c8\ub2e4. \ud558\uc9c0\ub9cc \uae30\ubcf8 \ud654\ud559\uc801 \ubb38\uc81c\ub97c \ud574\uacb0\ud558\uc9c0\ub294 \uc54a\uc2b5\ub2c8\ub2e4: \uc801\uc808\ud55c \uae30\ub2a5 \uadf8\ub8f9\ub4e4\uc740 \uc11c\ub85c \ubc18\uc751\ud574\uc57c \ud558\uc9c0\ub9cc \ubd84\uc790\uc758 \ub2e4\ub978 \ubd80\ubd84\uc5d0\uc11c \ubc1c\uc0dd\ud558\ub294 \ubd80\uc801\uc808\ud55c \ubc18\uc751\ub4e4\uc740 \uc801\uc808\ud558\uac8c \uc720\uc9c0\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4. \uc81c\ud55c\uc801\uc785\ub2c8\ub2e4.<\/p>\n

\uacb0\ud569 \ud615\uc131, \ubcc0\ud658 \ubc0f \ud6a8\uc728\uc131\uc740 \uc11c\ub85c \ub2e4\ub978 \uac1c\ub150\uc785\ub2c8\ub2e4.<\/h3>\n

\ud3a9\ud0c0\uc774\ub4dc \uacb0\ud569\uc744 \uc124\uba85\ud560 \ub54c \uc790\uc8fc \uc0ac\uc6a9\ub418\ub294 \uba87 \uac00\uc9c0 \uc6a9\uc5b4\ub294 \uc11c\ub85c \ub2e4\ub978 \uc8fc\uc81c\ub97c \ub2e4\ub8e8\uace0 \uc788\uc5b4\ub3c4 \ube44\uc2b7\ud558\uac8c \ub4e4\ub9b4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ubcc0\ud658\uc740 \ud574\ub2f9 \ucd9c\ucc98 \uc790\ub8cc\uc758 \uc5b4\ub5a4 \ubd80\ubd84\uc5d0 \ubc18\uc751\uc774 \uc77c\uc5b4\ub0ac\ub294\uc9c0 \uc815\uc758\ud569\ub2c8\ub2e4.<\/p>\n

\ud558\uc9c0\ub9cc \uadf8 \uc790\ub8cc\uac00 \uc5b4\ub5a4 \ud615\ud0dc\ub85c \ubcc0\ud615\ub418\uc5c8\ub294\uc9c0\ub294 \uc790\ub3d9\uc73c\ub85c \ub9d0\ud558\uc9c0\ub294 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub9cc\uc57d 99\uac1c\uc758% \uc6d0\ub8cc\uac00 \uc0ac\ub77c\uc9c0\ub354\ub77c\ub3c4 \uadf8 \uc77c\ubd80\uac00 \uc6d0\uce58 \uc54a\ub294 \ubd80\uc791\uc6a9 \uc131\ubd84\uc744 \uc0dd\uc131\ud55c\ub2e4\uba74, 99%\uc758 \ubcc0\ud658\uc740 \uc758\ub3c4\ub41c \ud3a9\ud2f0\ub4dc\uac00 \uc0dd\uc131\ub418\uc5c8\ub2e4\ub294 \uac83\uc744 \uc758\ubbf8\ud558\uc9c0 \uc54a\ub294\ub2e4.<\/p>\n

\ucd5c\uc885 \uc81c\ud488\uc758 \uc0dd\uc131\uc740 \ub2e4\ub978 \uc9c8\ubb38\uc5d0 \ub2f5\ud569\ub2c8\ub2e4: \uc2e4\uc81c\ub85c \uc5b4\ub5a4 \uc591\uc758 \uc758\ub3c4\ub41c \ubd84\uc790 \uad6c\uc870\uac00 \uc0dd\uc131\ub418\uc5c8\ub294\uac00? \uc774\uc5d0 \ub300\ud55c \ub2f5\uc740 \uc801\uc808\ud55c \uc81c\ud488\uc744 \uc911\uc694\ud55c \ub300\uc548 \uad6c\uc870\ub4e4\ub85c\ubd80\ud130 \uad6c\ubcc4\ud560 \uc218 \uc788\ub294 \ubd84\uc11d \ubc29\ubc95\uc744 \ud544\uc694\ub85c \ud569\ub2c8\ub2e4.<\/p>\n

\ubd84\ub9ac\ub41c \uc0dd\uc0b0\uc131\uc740 \uc815\uc758\ub41c \ucd08\uae30 \uc7ac\ub8cc \uc591\uc5d0 \ube44\ub840\ud558\uc5ec \ucd5c\uc885\uc801\uc73c\ub85c \ud68c\uc218\ub41c \ud2b9\uc815 \uc81c\ud488\uc758 \uc591\uc744 \uc124\uba85\ud569\ub2c8\ub2e4. \ub530\ub77c\uc11c \ucd5c\uc885 \uc0dd\uc0b0\ub7c9\uc5d0\ub294 \uac00\uacf5, \ubd84\ub9ac \ubc0f \uc138\uc815 \ub2e8\uacc4\ub3c4 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc790\uccb4 \uacb0\ud569 \uacfc\uc815\uc774 \ud6a8\uacfc\uc801\uc73c\ub85c \uc9c4\ud589\ub418\uc5c8\ub354\ub77c\ub3c4 \ub9c8\ucc2c\uac00\uc9c0\uc785\ub2c8\ub2e4.<\/p>\n

\uc0c9\uc18c \ubd84\uc11d\uc740 \ud2b9\uc815 \uc0c9\uc18c \ubd84\uc11d \ubc29\ubc95\uc758 \uc870\uac74 \ud558\uc5d0\uc11c \uac80\ucd9c\ub418\ub294 \uc131\ubd84\uc758 \ubd84\uc0b0\uc744 \uc124\uba85\ud569\ub2c8\ub2e4. \uadf8\uac83\uc740 \uc2dc\ub8cc\uc758 \uc131\ubd84\uc5d0 \ub300\ud55c \ub9e4\uc6b0 \uc720\uc6a9\ud55c \uc815\ubcf4\ub97c \uc81c\uacf5\ud560 \uc218 \uc788\uc9c0\ub9cc, \ud574\uc11d\uc740 \uc870\ud654\uc131, \ud0d0\uc9c0\uae30\uc758 \ubc18\uc751 \ucc28\uc774 \ub610\ub294 \uc874\uc7ac \uc5ec\ubd80\uc5d0 \uc758\ud574 \uc81c\ud55c\ub420 \uc218 \uc788\ub2e4. \ud2b9\uc815 \ubc29\ubc95\uc73c\ub85c \uc798 \uac80\ucd9c\ub418\uc9c0 \uc54a\ub294 \uc131\ubd84\ub4e4.<\/p>\n

\ubc18\ub300\ud3b8\uc73c\ub85c\ub294, \ub3d9\uc801 \uc2a4\ud2f0\uc5b4\uc624\ubbf9\uc2a4(stereochemistry)\uac00 \ubd84\uc790\uc758 \ubaa9\uc801\ud55c \uacf5\uac04\uc801 \uad6c\uc131\uc774 \uc720\uc9c0\ub418\uc5c8\ub294\uc9c0 \uc5ec\ubd80\ub97c \ubb3b\ub294 \uc9c8\ubb38\uc5d0 \ub2f5\ud569\ub2c8\ub2e4. \uc774\uac83\uc740 \ubd84\uc11d\uc801\uc778 \ubcc4\uac1c\uc758 \ubb38\uc81c\uc774\uba70, \uc77c\ubd80 \ub3d9\uc801 \uc2a4\ud2f0\uc5b4\uc624\ubbf9\uc2a4 \ubcc0\ud615\uc740 \ucd5c\uc885 \uc81c\ud488\uacfc \uc815\ud655\ud788 \ub3d9\uc77c\ud55c \ubd84\uc790 \uc9c8\ub7c9\uc744 \uac00\uc9c8 \uc218 \uc788\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4.<\/p>\n

\uc774\ub7ec\ud55c \ucc28\uc774\uc810\ub4e4\uc740 \ucc98\uc74c\uc5d0\ub294 \ubaa8\uc21c\uc801\uc73c\ub85c \ubcf4\uc77c \uc218 \uc788\ub294 \uacb0\uacfc\ub4e4\uc744 \uc774\ud574\ud558\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub429\ub2c8\ub2e4.<\/p>\n

\uc774 \ubc18\uc751\uc740 \ucd9c\ucc98 \ubb3c\uc9c8\uc758 \ub192\uc740 \uc804\ud658\uc728\uc744 \ub098\ud0c0\ub0bc \uc218 \uc788\uc9c0\ub9cc, \ub3d9\uc2dc\uc5d0 \uc5ec\ub7ec \uac00\uc9c0 \uc81c\ud488\uc758 \uc0dd\uc131\uc73c\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc0dd\uc131\ub41c \uc6d0\ub8cc\ub294 \ud070 \uc591\uc758 \uc7ac\uc21c\ud658 \ubb3c\uc9c8\uc744 \ud568\uc720\ud560 \uc218 \uc788\uc9c0\ub9cc \uc0c1\ub2f9\ud55c \uc591\uc758 \uc624\uc5fc \ubb3c\uc9c8\uc744 \ud3ec\ud568\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ubc18\uba74, \uac15\ud55c \uc138\uc815 \uacfc\uc815\uc740 \ub0ae\uc740 \uc131\ub2a5\uc758 \ub2e8\ub3c5 \uc808\uc5f0\uc7ac\ub97c \uc0ac\uc6a9\ud558\uba74\uc11c\ub3c4 \ub192\uc740 \uc21c\ub3c4\uc758 \uc7ac\ub8cc\ub97c \uc5bb\uc744 \uc218 \uc788\uac8c \ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc774\ub7ec\ud55c \uad00\uce21\ub4e4 \uc911 \uc5b4\ub290 \uac83\ub3c4 \uc2a4\uc2a4\ub85c \ub2e4\ub978 \uad00\uce21\ub4e4\uacfc \ubaa8\uc21c\ub418\uc9c0 \uc54a\ub294\ub2e4.<\/p>\n

\uadf8\ub4e4\uc740 \ub2e8\uc21c\ud788 \uc81c\ud488\uc758 \ub2e4\uc591\ud55c \ud2b9\uc131\uc774\ub098 \ud504\ub85c\uc138\uc2a4\uc758 \ub2e4\uc591\ud55c \ub2e8\uacc4\ub97c \uc124\uba85\ud569\ub2c8\ub2e4.<\/p>\n

\ub530\ub77c\uc11c \u201e\uce21\uc815\uc740 \uc644\uc804\ud588\ub2e4\u201d\ub77c\ub294 \uc9c4\uc220\uc740 \uce21\uc815\ub41c \ubd84\uc11d \ubc29\ubc95\uacfc \uc815\ud655\ud788 \uce21\uc815\ub41c \ud56d\ubaa9\uc5d0 \ub300\ud574\uc11c\ub3c4 \uc54c\uba74 \ud6e8\uc52c \ub354 \ud070 \uac00\uce58\ub97c \uc9c0\ub2c8\uac8c \ub429\ub2c8\ub2e4.<\/p>\n

\uc5b4\ub824\uc6b4 \uc18c\uc7ac\ub294 \ud504\ub85c\uc138\uc2a4\uc758 \ub2e4\uc591\ud55c \ud55c\uacc4\ub97c \ub4dc\ub7ec\ub0b8\ub2e4.<\/h3>\n

\ud3a9\ud0c0\uc774\ub4dc \uacb0\ud569 \ubc18\uc751\uc758 \ubaa8\ub4e0 \ubc18\uc751\uc774 \ub3d9\uc77c\ud55c \uc218\uc900\uc758 \ud654\ud559\uc801 \uc5b4\ub824\uc6c0\uc744 \ub3d9\ubc18\ud558\ub294 \uac83\uc740 \uc544\ub2d9\ub2c8\ub2e4.<\/p>\n

\uac15\ud558\uac8c \ucda9\uc804\ub41c \ubc18\uc751\uc131 \uc704\uce58\ub294 \ubc18\uc751 \uadf8\ub8f9\ub4e4\uc774 \uc11c\ub85c\uc758 \uc811\uadfc\uc744 \ubc29\ud574\ud558\uae30 \ub54c\ubb38\uc5d0 \uacb0\ud569\ubb3c\uc758 \uc0dd\uc131 \uc18d\ub3c4\ub97c \uc800\ud574\ud560 \uc218 \uc788\ub2e4.<\/p>\n

\uc57d\ud55c \uc6a9\ud574\ub3c4\ub294 \ubc18\uc751 \uc131\ubd84\ub4e4 \uac04\uc758 \ud6a8\uacfc\uc801\uc778 \uc811\ucd09\uc744 \uc81c\ud55c\ud560 \uc218 \uc788\ub2e4.<\/p>\n

\uc0c1\uc218 \ub2e8\uacc4\uc5d0\uc11c\uc758 \ud569\uc131\uc5d0\uc11c\ub294 \uc131\uc7a5\ud558\ub294 \ud3a9\ud2f0\ub4dc \uc0ac\uc2ac\uc774 \uc8fc\ubcc0 \uc0ac\uc2ac\ub4e4\uacfc \uc0c1\ud638 \uc791\uc6a9\ud558\uac70\ub098 \ubc18\uc751 \uc0ac\uc774\ud2b8 \uc811\uadfc\uc744 \uc81c\ud55c\ud558\ub294 \uad6c\uc870\ub4e4\uc744 \uc218\uc6a9\ud560 \uc218 \uc788\uc73c\uba70, \uc811\ud569 \ucd09\ub9e4\ub4e4\uc774 \ud604\uc0c1\uc801\uc73c\ub85c \uacfc\ub2e4\ud558\uac8c \uc874\uc7ac\ud558\ub354\ub77c\ub3c4 \ub9c8\ucc2c\uac00\uc9c0\uc774\ub2e4.<\/p>\n

\uc774\ub7ec\ud55c \ubb38\uc81c\ub294 \ub2e4\uc591\ud55c \ud654\ud559\uc801 \uc6d0\ub9ac\ub97c \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub530\ub77c\uc11c \ud55c \uac00\uc9c0 \ud574\uacb0\ucc45\uc774 \ubaa8\ub4e0 \uacbd\uc6b0\uc5d0 \uc790\ub3d9\uc73c\ub85c \ud6a8\uacfc\uac00 \uc788\uc744 \uac83\uc774\ub77c\uace0 \uae30\ub300\ud560 \uc218\ub294 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc5b4\ub824\uc6b4 \ud3a9\ud2f0\ub4dc \uc11c\uc5f4\uc5d0 \ub300\ud55c \ubc18\ubcf5 \uacb0\ud569 \uc804\ub7b5\uc744 \ube44\uad50\ud55c \uc5f0\uad6c\ub4e4\uc740 \uc218\ub4dd\ub41c \uc6d0\ub8cc \uc81c\ud488\uc758 \uc2e4\uc81c \uc131\ubd84\uc744 \ubd84\uc11d\ud588\uc73c\uba70, \ud3c9\uac00\ub97c \uc804\uc801\uc73c\ub85c \uc774\ub860\uc801 \ubc18\uc751\uc131\uc5d0\ub9cc \uc758\uc874\ud558\uc9c0 \uc54a\uc558\ub2e4. \ub610\ub294 \uac1c\ubcc4 \ucd09\ub9e4\ubb3c\uc758 \ud3c9\ud310\uc785\ub2c8\ub2e4. \uac80\uc0ac\ub41c \uc804\ub7b5 \uc911 \ud558\ub098\ub294 \ubd84\uc11d\ub41c \ubaa8\ub378\uc5d0\uc11c \uc720\uc758\ubbf8\ud55c \uacb0\uacfc\ub97c \ubcf4\uc600\uc9c0\ub9cc, \uc774\ub294 \ubaa8\ub4e0 \ud53c\uc5d0\ub2e4 \uc5fc\uae30 \uc11c\uc5f4\uc5d0 \uc801\ud569\ud55c \uc804\uc6a9 \uc194\ub8e8\uc158\uc774 \uc874\uc7ac\ud55c\ub2e4\ub294 \uac83\uc744 \uc758\ubbf8\ud558\uc9c0\ub294 \uc54a\ub294\ub2e4.<\/p>\n

\uac00\uc7a5 \uc911\uc694\ud55c \uc81c\uc548\uc740 \ud574\ub2f9 \ubc29\ubc95\uc758 \ud6a8\uacfc\ub97c \ud2b9\uc815 \uc11c\ube0c\uc2a4\ud2b8\ub77c\ud22c\uc5d0\uc11c \uc5bb\uc5b4\uc9c4 \uc81c\ud488\uc744 \uae30\uc900\uc73c\ub85c \ud3c9\uac00\ud574\uc57c \ud55c\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4. \uc774\ub294 \uc0ac\uc6a9\ub41c \ucd09\ub9e4\uc758 \ud3c9\ud310\uc744 \uae30\uc900\uc73c\ub85c \ud55c \uac83\uc774 \uc544\ub2d9\ub2c8\ub2e4.<\/p>\n

\ubd80\ud638\ud654 \uadf8\ub8f9 \ud65c\uc131\ud654<\/h2>\n

\uc65c \ud65c\uc131\ud654\uac00 \ubcf4\ud1b5 \ud544\uc694\ud569\ub2c8\uae4c?<\/h3>\n

\uc77c\ubc18\uc801\uc778 \uc870\uac74\uc5d0\uc11c \ubb34\uc815\uc81c\ub41c \uce74\ubcf4\uc625\uc2dc\uc0b0\uacfc \uc544\ubbf8\ub178\ub97c \ud63c\ud569\ud558\ub294 \uac83\ub9cc\uc73c\ub85c\ub3c4 \uc77c\ubc18\uc801\uc73c\ub85c \uc815\ubc00\ud55c \ud53c\ub864\ub9ac\ub4dc \uacb0\ud569\uc744 \uc0dd\uc131\ud558\ub294 \ub370\ub294 \ud6a8\uacfc\uc801\uc73c\ub85c \ub3c4\uc6c0\uc774 \ub418\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub300\uc2e0 \uc0b0-\uc218\uc18c \uc791\uc6a9\uc774 \uc77c\uc5b4\ub0a0 \uc218 \uc788\uc73c\uba70, \ud6a8\uacfc\uc801\uc778 \uc544\ubbfc \uacb0\ud569 \uc0dd\uc131\uc5d0\ub294 \uc801\uc808\ud55c \ud654\ud559 \uacbd\ub85c\uac00 \ud544\uc694\ud569\ub2c8\ub2e4.<\/p>\n

\ub530\ub77c\uc11c \ud3a9\ud2f0\ub4dc \uacb0\ud569\uc740 \uc77c\ubc18\uc801\uc73c\ub85c \uce74\ubcf5\uc2e4 \uadf8\ub8f9\uc744 \ud3ec\ud568\ud558\ub294 \uc131\ubd84\uc744 \ud65c\uc131\ud654\uc2dc\ud0a4\ub294 \uac83\uc744 \ud3ec\ud568\ud569\ub2c8\ub2e4.<\/p>\n

\ud65c\uc131\ud654\ub294 \uadf8\uc640 \uad00\ub828\ub41c \uc544\ubbfc \uadf8\ub8f9\uacfc \ubc18\uc751\ud558\ub294 \ub2a5\ub825\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4. \uc801\uc808\ud55c \ubc18\uc751 \ud658\uacbd\uacfc \uc801\uc808\ud55c \ud0c8\ucc29 \uadf8\ub8f9\uc740 \uc0c8\ub85c\uc6b4 \uc544\ubbfc \uacb0\ud569\uc744 \uc0dd\uc131\ud558\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub429\ub2c8\ub2e4.<\/p>\n

\ud65c\uc131\ud654\ub41c \uc911\uac04 \uc81c\ud488\uc740 \ub2e8\uae30\uac04 \ub3d9\uc548\ub9cc \uc874\uc7ac\ud560 \uc218 \uc788\uc73c\uba70, \ubd84\ub9ac\ub418\uc5b4\uc57c \ud560 \ud544\uc694\ub294 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \ubaa9\ud45c\ub294 \uac00\ub2a5\ud55c \ucd5c\ub300\uc758 \ud654\ud559 \ubc18\uc751\uc131\uc744 \uc5bb\ub294 \uac83\uc774 \uc544\ub2d9\ub2c8\ub2e4.<\/p>\n

\ubaa9\ud45c\ub294 \uc81c\uc5b4\ub41c \ubc18\uc751\uc131\uc785\ub2c8\ub2e4.<\/p>\n

\ubb3c\uacfc \ub9e4\uc6b0 \ube60\ub974\uac8c \ubc18\uc751\ud558\uac70\ub098 \ub2e4\ub978 \ubd88\ud544\uc694\ud55c \ub274\ud074\ub808\uc624\ud30c\uc77c\uacfc \ubc18\uc751\ud558\uac70\ub098 \uacbd\uc7c1\uc801\uc778 \ubc18\uc751\uc5d0 \ucc38\uc5ec\ud558\ub294 \ud65c\uc131\ud654\ub41c \uc911\uac04\uccb4\ub294 \ube60\ub974\uac8c \uc0ac\ub77c\uc9c8 \uc218 \uc788\uc9c0\ub9cc, \ub3d9\uc2dc\uc5d0 \uc758\ub3c4\ub41c \ud3a9\ud2f0\ub4dc\uc758 \uc591\uc774 \uc0c1\ub300\uc801\uc73c\ub85c \uc801\uac8c \uc0dd\uc131\ub420 \uc218 \uc788\ub2e4.<\/p>\n

\ub530\ub77c\uc11c \ub192\uc740 \ubc18\uc751\uc131\uc740 \uc758\ub3c4\ub41c \uacb0\ud569\uc744 \ud615\uc131\ud558\uae30 \uc704\ud574 \uc801\uc808\ud788 \uc870\uc808\ud560 \uc218 \uc788\ub294 \uacbd\uc6b0\uc5d0\ub9cc \uc720\uc6a9\ud569\ub2c8\ub2e4.<\/p>\n

\uc811\ucc29\uc81c \ubc0f \ucca8\uac00\uc81c\ub294 \ub2e4\uc591\ud55c \uae30\ub2a5\uc744 \uc218\ud589\ud569\ub2c8\ub2e4.<\/h3>\n

\ud3a9\ud2f0\ub4dc\ub4e4\uc758 \uacb0\ud569\uc5d0\ub294 \ub2e4\uc591\ud55c \uae30\ub2a5\ub4e4\uc744 \uc218\ud589\ud558\ub294 \uc5ec\ub7ec \uc885\ub958\uc758 \ud654\ud559 \uc131\ubd84\uc774 \ucc38\uc5ec\ud560 \uc218 \uc788\ub2e4.<\/p>\n

\uce74\ub974\ubcf4\ub514\uc774\ubbf8\ub4dc\ub294 \ubcf4\ub974\ub3c4\uc0b0\ud654\uae30\uc758 \ud65c\uc131\ud654\uc5d0 \uc0ac\uc6a9\ub418\ub294 \ucd09\ub9e4\uc758 \ud55c \uadf8\ub8f9\uc744 \uad6c\uc131\ud569\ub2c8\ub2e4.<\/p>\n

\ub2e4\ub978 \uacb0\ud569 \uc2dc\uc2a4\ud15c\uc740 \uc885\uc885 HATU \uae30\ubc18 \uc2dc\uc2a4\ud15c\uacfc \uac19\uc740 \uc624\ub178\uc774 \uc2dc\uc2a4\ud15c\uacfc \uac19\uc740 \ub2e4\ub978 \ud65c\uc131\ud654 \uba54\ucee4\ub2c8\uc998\uc744 \uc0ac\uc6a9\ud569\ub2c8\ub2e4.<\/p>\n

\ucd94\uac00 \ud654\ud569\ubb3c\uc740 \ucca8\uac00\ubb3c \uc5ed\ud560\uc744 \ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \u201e\ucd94\uac00\ubb3c\u2019\uc774\ub77c\ub294 \uc6a9\uc5b4\ub294 \ud574\ub2f9 \ud654\ud569\ubb3c\uc774 \ud654\ud559\uc801\uc73c\ub85c \uc911\uc694\ud558\uc9c0 \uc54a\ub2e4\ub294 \uac83\uc744 \uc758\ubbf8\ud558\uc9c0\ub294 \uc54a\uc2b5\ub2c8\ub2e4. \ucd94\uac00\ubb3c\uc740 \uc911\uac04\ubb3c, \uacb0\ud569 \ud6a8\uc728, \uacbd\uc7c1\uc801\uc778 \ubc18\uc751 \uacbd\ub85c, \uadf8\ub9ac\uace0 stereochemical \uacb0\uacfc\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc624\ud0a4\ub9c8\ub97c \uc774\uc6a9\ud55c \uce74\ub974\ubcf4\ub514\uc774\ubbf8\ub4dc \uae30\ubc18 \ud3a9\ud2f0\ub4dc \ud569\uc131 \uc5f0\uad6c\ub294 \uc120\ud0dd\ub41c \ubaa8\ub378\uc5d0\uc11c \uacb0\ud569 \ud6a8\uc728\uc131\uacfc \ub77c\uc138\ub9c8\uc774\uc988 \uc5b5\uc81c \ud6a8\uacfc\ub97c \ubaa8\ub450 \ubd84\uc11d\ud588\ub2e4.<\/p>\n

\uc774\ub7ec\ud55c \ub370\uc774\ud130\ub294 \uc5f0\uad6c \ub300\uc0c1 \uc2dc\uc2a4\ud15c\uacfc \ud2b9\uc815 \ubaa8\ub378\uc5d0 \uc720\uc6a9\ud569\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \uc774\uac83\ub4e4\uc740 \ubaa8\ub4e0 \uac00\ub2a5\ud55c \ud3a9\ud2f0\ub4dc \uacb0\ud569 \uc870\uac74\uc5d0\uc11c \ub3d9\uc77c\ud55c \ud654\ud569\ubb3c\uc744 \uc0ac\uc6a9\ud558\uba74 \ub3d9\uc77c\ud55c \uacb0\uacfc\ub97c \uc5bb\uc744 \uac83\uc774\ub77c\ub294 \uac83\uc744 \uc758\ubbf8\ud558\uc9c0\ub294 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc774\ud6c4 \uc9c4\ud589\ub41c Oxyma-B \uc5f0\uad6c\uc5d0\uc11c\ub294 \uba87 \uac00\uc9c0 \ubaa8\ub378 \ub2e8\ubc31\uc9c8\uc5d0\uc11c \uad11\ud559 \uc21c\ub3c4\ub97c \ube44\uad50\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub2e4\uc218\uc758 \uae30\uc7ac\ubb3c\uc5d0 \ub300\ud55c \uc5f0\uad6c\ub294 \ud2b9\ud788 \uc911\uc694\ud569\ub2c8\ub2e4. \uc65c\ub0d0\ud558\uba74 \uc6a9\uc774\ud558\uac8c \ud654\ud559\uc801\uc73c\ub85c \uacb0\ud569\ub418\ub294 \ub9e4\uc6b0 \uc6b0\uc218\ud55c \uacb0\uacfc\uac00 \uc815\uc804\ud558\uc5d0 \ubbfc\uac10\ud558\uac70\ub098 \ud3b8\ud5a5\uc801 \uad6c\uc870\ub97c \uac00\uc9c4 \uc7a5\uc18c\uc5d0\uc11c \ucd09\ub9e4\uc758 \ud589\ub3d9\uc744 \uc608\uce21\ud560 \ud544\uc694\uac00 \uc5c6\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4.<\/p>\n

\ud3a9\ud0c0\uc774\ub4dc \ud569\uc131\uc5d0 HATU\ub780 \ubb34\uc5c7\uc744 \uc758\ubbf8\ud558\ub294\uac00?<\/h3>\n

HATU\ub294 \uc544\ubbf8\ub4dc \uacb0\ud569 \uc0dd\uc131\uc758 \ucd09\uc9c4\uc5d0 \uc0ac\uc6a9\ub418\ub294 \ucd09\ub9e4\uc81c\ub85c, \ud2b9\ud788 \ud3a9\ud2f0\ub4dc \ud569\uc131\uc5d0 \uc0ac\uc6a9\ub429\ub2c8\ub2e4.<\/p>\n

HATU\ub294 \ud3a9\ud0c0\uc774\ub4dc\uac00 \uc544\ub2d9\ub2c8\ub2e4.<\/p>\n

\uadf8\ub4e4\uc740 \ub610\ud55c \ubcf4\ud638 \ub2e8\uccb4\ub3c4 \uc544\ub2d9\ub2c8\ub2e4.<\/p>\n

\uadf8\uc758 \uc874\uc7ac \uc790\uccb4\ub85c\ub294 \uacb0\ud569\uc774 \uc644\ub8cc\ub418\uc5c8\uc74c\uc744 \uc785\uc99d\ud558\uac70\ub098, \uc218\uc2e0\ub41c \ud3a9\ud2f0\ub4dc\uac00 \uc21c\uc218\ud568\uc744 \ubcf4\uc7a5\ud558\ub294 \uac83\uc740 \uc544\ub2d9\ub2c8\ub2e4.<\/p>\n

\ud6a8\uacfc\ub294 \uc18c\uc7ac\uc758 \uc885\ub958, \ub2e4\ub978 \ucd09\ub9e4\ub4e4, \uc6a9\ub9e4 \uc2dc\uc2a4\ud15c \uadf8\ub9ac\uace0 \ubc18\uc751 \uc870\uac74\uc758 \ub354 \ub113\uc740 \ub9e5\ub77d\uc5d0 \ub530\ub77c \ub2ec\ub77c\uc9c4\ub2e4.<\/p>\n

\ud569\uc131 \uac00\ub2a5\uc131 \ub192\uc740 \uc11c\uc5f4 \ubd84\uc11d\uc740 \ubc18\ubcf5 \uacb0\ud569 \uc870\uac74\uc5d0\uc11c HATU \uae30\ubc18 \uc811\uadfc\ubc95\uacfc Oxyma\/carbodimide \uc2dc\uc2a4\ud15c\uc744 \ud3ec\ud568\ud558\uc5ec \ube44\uad50\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc774\ub294 \u201eHATU peptide\u201d\uc640 \uac19\uc740 \uac80\uc0c9\uc5b4\ub97c \ud569\uc131 \ubc0f \uc120\ud0dd \ubc29\ubc95\uc758 \ud654\ud559\uc5d0 \uad00\ud55c \uc9c8\ubb38\uc73c\ub85c \uc774\ud574\ud574\uc57c \ud55c\ub2e4\ub294 \uac83\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4. \uc774\ub294 \ud2b9\uc815 \ud654\ud569\ubb3c\uc774 \ud3a9\ud2f0\ub4dc \ud569\uc131\uc758 \ubcf4\ud3b8\uc801 \ubc29\ubc95\uc774\ub77c\ub294 \uac83\uc744 \uc785\uc99d\ud558\ub294 \uac83\uc774 \uc544\ub2d9\ub2c8\ub2e4.<\/p>\n

\ubd84\uc11d\uc81c\uc758 \uc774\ub984 \uc790\uccb4\ub85c\ub294 \ubc1c\ud45c\ub41c \uacb0\uacfc\uc758 \uc815\ud655\ud55c \uc7ac\ud604\uc774\ub098 \uc801\uc808\ud55c \ud574\uc11d\uc744 \ub4b7\ubc1b\uce68\ud560 \uc218 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n

\ubc18\uc751 \uc870\uac74, \ub2e8\ubc31\uc9c8 \uc11c\uc5f4 \ubc0f \ud504\ub85c\uc138\uc2a4\uc758 \uc131\uacf5\uc744 \ubd84\uc11d\uc801\uc73c\ub85c \uc815\uc758\ud558\ub294 \ubc29\ubc95\ub3c4 \uc911\uc694\ud569\ub2c8\ub2e4.<\/p>\n

\uc2a4\ud14c\ub808\uc624\uc2dc\ubbf9 \ud65c\uc131\ud654 \ubc0f \uc81c\uc5b4\ub294 \uade0\ud615\uc744 \uc720\uc9c0\ud558\ub294 \uac83\uc744 \ud544\uc694\ub85c \ud55c\ub2e4.<\/h3>\n

\ud65c\uc131\ud654\ub41c \uc544\ubbf8\ub178\uc0b0 \uc720\ub3c4\uccb4\uc758 \uc7a5\uae30 \uc720\uc9c0\ub294 \ud56d\uc0c1 \uc720\uc775\ud55c \uac83\uc740 \uc544\ub2d9\ub2c8\ub2e4.<\/p>\n

\uc6d0\ud558\ub294 \uacb0\ud569 \ubc18\uc751\uc740 \ub2e4\ub978 \uac00\ub2a5\ud55c \ud654\ud559 \uacfc\uc815\ub4e4\uacfc \ud568\uaed8 \uc77c\uc5b4\ub09c\ub2e4.<\/p>\n

\uc77c\ubd80 \uacbd\uc7c1\uc801\uc778 \uacbd\ub85c\ub4e4\uc740 \uc2a4\ud14c\ub808\uc624\ud0c0\uc785\uc744 \ubcc0\ud654\uc2dc\ud0ac \uc218 \uc788\ub2e4.<\/p>\n

\ubcf4\ud638\ub41c \uc5d0\ud53c\uba54\ub9ac\uce5c \uc81c\ud488\uc5d0 \ub300\ud55c \uc2e4\ud5d8\uc801 \uc5f0\uad6c\ub294 \uc544\ubbf8\ub178\uc0b0, \uc6a9\ub9e4 \ubc0f \uae30\ud0c0 \ubc18\uc751 \uc131\ubd84\ub4e4\uc758 \uc870\ud569\uc774 \uce74\ub974\ubcf4\ub514\uc774\ubbf8\ub4dc \ucc38\uc5ec\ud558\uc758 \uacb0\ud569 \uacfc\uc815\uc5d0\uc11c \ubc1c\uc0dd\ud558\ub294 \ud3b8\ud5a5\uc801 \ubcc0\ud654\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5\uc744 \ubd84\uc11d\ud558\uc600\ub2e4.<\/p>\n

\uc774\ub294 \uc911\uc694\ud55c \uc6d0\uce59\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4: \ubc18\uc751 \ud658\uacbd \uc804\uccb4\ub294 \uc0ac\uc6a9\ub41c \uc811\ud569 \ucd09\ub9e4\uc758 \uc77c\ubc18\uc801\uc778 \uc9d1\ub2e8\ub9cc\ud07c\uc774\ub098 \uc911\uc694\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub530\ub77c\uc11c \uacb0\ud569 \uc804\ub7b5\uc740 \ubc14\ub78c\uc9c1\ud55c \uacb0\ud569\uc744 \ud615\uc131\ud558\uae30 \uc704\ud55c \ucda9\ubd84\ud55c \ubc18\uc751\uc131\uc744 \uc81c\uacf5\ud574\uc57c \ud558\uba70, \ub3d9\uc2dc\uc5d0 \ubc14\ub78c\uc9c1\ud558\uc9c0 \uc54a\uc740 \ubc18\uc751\uc758 \ubc1c\uc0dd \uac00\ub2a5\uc131\uc744 \uc81c\ud55c\ud574\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\uc774\ub7ec\ud55c \uc6d0\uce59\ub4e4\uc740 \uc644\uc131\ub41c \uc2e4\ud5d8 \ud504\ub85c\ud1a0\ucf5c\ub85c \ubcc0\ud658\ud558\uc9c0 \uc54a\uace0 \uad50\uc721 \ubaa9\uc801\uc73c\ub85c \ub17c\uc758\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud65c\uc131\uc81c\ub4e4\uc758 \uc815\ud655\ud55c \uc591, \ucd94\uac00 \uc21c\uc11c \ubc0f \ubc18\uc751 \uc870\uac74\uc740 \uac1c\ubc1c \uc911\uc778 \ud569\uc131 \uacf5\uc815\uc5d0 \ub530\ub77c \ub2ec\ub77c\uc9d1\ub2c8\ub2e4.<\/p>\n

\ubcf4\ud638 \ub2e8\uccb4\uc758 \uc5ed\ud560<\/h2>\n

\ubcf4\uc548\uc740 \uacbd\uc7c1\uc801\uc778 \ub300\uc751 \uacf5\uac04\uc744 \uc81c\ud55c\ud55c\ub2e4.<\/h3>\n

\uc544\ubbf8\ub178\uc0b0\uc740 \ub2e8\uc9c0 \uc544\ubbf8\ub178\uae30\uc640 \ubcf4\ub974\uae30\uc0b0\uae30\uac00 \uc544\ub2cc \ub2e4\ub978 \ubc18\uc751 \uadf8\ub8f9\uc744 \ud3ec\ud568\ud560 \uc218 \uc788\uc73c\uba70, \uc774\uac83\ub4e4\uc740 \uc544\ubbf8\ub4dc \uad6c\uc870\ub97c \ud615\uc131\ud558\ub294 \ub370 \ud544\uc694\ud569\ub2c8\ub2e4.<\/p>\n

\uadf8\uc758 \uce21\uba74 \ub9c1\uc740 \ucd94\uac00\uc801\uc778 \ubc18\uc751\uc131 \ud654\ud559 \uadf8\ub8f9\uc744 \ud3ec\ud568\ud560 \uc218 \uc788\ub2e4.<\/p>\n

\ub9cc\uc57d \ubaa8\ub4e0 \uc7a0\uc7ac\uc801\uc73c\ub85c \ubc18\uc751\uc131 \uadf8\ub8f9\ub4e4\uc774 \uacb0\ud569 \uacfc\uc815\uc758 \ubaa8\ub4e0 \ub2e8\uacc4\uc5d0\uc11c \ub178\ucd9c\ub418\uc5b4 \uc788\ub2e4\uba74, \ud53c\ud398\ud2f0\ub4dc \uacb0\ud569\uc758 \uc0dd\uc131\uc740 \ubd84\ud574 \ub610\ub294 \uae30\ud0c0 \ubd88\ud544\uc694\ud55c \ubc18\uc751\uacfc \uacbd\uc7c1\ud560 \uc218 \uc788\uc5c8\uc744 \uac83\uc785\ub2c8\ub2e4.<\/p>\n

\ubcf4\ud638 \uadf8\ub8f9\uc744 \ud65c\uc6a9\ud558\ub294 \uc804\ub7b5\uc740 \uc120\ud0dd\ub41c \ubc18\uc751 \uc7a5\uc18c\ub97c \uc77c\uc2dc\uc801\uc73c\ub85c \uac00\ub824\uc90d\ub2c8\ub2e4.<\/p>\n

\uadf8 \ub355\ubd84\uc5d0 \uc801\uc808\ud55c \uc544\ubbf8\ub178 \ubc0f \uce74\ubcf5\uc2e4 \uadf8\ub8f9\ub4e4\uc740 \uc11c\ub85c \ubc18\uc751\ud560 \uc218 \uc788\uc9c0\ub9cc, \ub2e4\ub978 \uc704\uce58\ub4e4\uc740 \ud574\ub2f9 \uc870\uac74\uc5d0\uc11c \ubc18\uc751\uc131\uc774 \ubd80\uc871\ud558\uac70\ub098 \ucda9\ubd84\ud788 \ub0ae\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub530\ub77c\uc11c \ubcf4\ud638\uc81c\ub294 \ud654\ud559\uc801 \uc120\ud0dd\uc131\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \ud6a8\uacfc\uc801\uc778 \uc804\ub7b5\uc740 \ub2e8\uc9c0 \ud654\ud559\uc801\uc73c\ub85c \uc548\uc815\uc801\uc778 \ud654\ud569\ubb3c\uc744 \uacb0\ud569\ud558\ub294 \uac83\ub9cc\uc73c\ub85c\ub294 \ucda9\ubd84\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n

\uadf8 \ud6c4\uc5d0\ub294 \ubcf4\ud638\uad70 \uadf8\ub8f9\ub3c4 \uc81c\uac70\ud574\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\uc5f0\uacb0 \uc2dc \ubd88\ud544\uc694\ud55c \ubc18\uc751\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \ubc29\uc9c0\ud558\ub294 \ubcf4\ud638\ub9c9\uc774\uc9c0\ub9cc, \uc774\ud6c4 \ubaa9\uc801 \ub2e8\uc704\ub97c \uc190\uc0c1\uc2dc\ud0a4\uc9c0 \uc54a\uace0 \uc81c\uac70\ud560 \uc218 \uc5c6\uc73c\uba74 \ub610 \ub2e4\ub978 \ud569\uc131 \ubb38\uc81c\uac00 \ubc1c\uc0dd\ud569\ub2c8\ub2e4.<\/p>\n

\ub530\ub77c\uc11c \uc644\uc804\ud55c \uc804\ub7b5\uc740 \ubcf4\ud638\uac00 \ud544\uc694\ud55c \uae30\uac04 \ub3d9\uc548\uc758 \uc548\uc815\uc131\uacfc \ud544\uc694\uc131\uc774 \uc0ac\ub77c\uc9c4 \ud6c4 \ubcf4\ud638\ub97c \uc120\ud0dd\uc801\uc73c\ub85c \uc81c\uac70\ud560 \uc218 \uc788\ub294 \ub2a5\ub825\uc744 \ubaa8\ub450 \uace0\ub824\ud574\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\uc77c\uc2dc\uc801 \ubc0f \uc7a5\uae30\uc801\uc778 \ubcf4\ud638 \uc870\uce58\ub294 \uc11c\ub85c \ub2e4\ub978 \uae30\ub2a5\uc744 \uc218\ud589\ud569\ub2c8\ub2e4.<\/h3>\n

\uac01 \ubcf4\ud638 \uadf8\ub8f9\uc740 \uc11c\ub85c \ub2e4\ub978 \uae30\uac04 \ub3d9\uc548 \ubd80\ubd84\uc801\uc73c\ub85c \uc874\uc7ac\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc77c\ubc18\uc801\uc778 Fmoc \ubcf4\ud638\ub97c \uc0ac\uc6a9\ud558\ub294 \uace0\uccb4 \ub2e8\uacc4 \ud569\uc131\uc5d0\uc11c\ub294 \uc131\uc7a5\ud558\ub294 \ud654\ud569\ubb3c\uc758 \uc544\ubbfc \uadf8\ub8f9\uc758 \ub05d\uc744 \uc81c\uac70\ud558\ub294 \uacfc\uc815\uc774 \uc2dc\ud000\uc2a4\uc758 \uae38\uc5b4\uc9d0\uc5d0 \ub530\ub77c \uc5ec\ub7ec \ubc88 \ubc18\ubcf5\ub429\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \ub9ce\uc740 \uce21\uba74 \ub9c1 \uadf8\ub8f9\ub4e4\uc740 \uc218\ub9ce\uc740 \uacb0\ud569 \uc8fc\uae30 \ub3d9\uc548 \uacc4\uc18d \uc874\uc7ac\ud558\uba70, \uadf8\ub4e4\uc740 \uc774\ud6c4 \ub2e8\uacc4\uc5d0\uc11c\uc57c \uc81c\uac70\ub429\ub2c8\ub2e4.<\/p>\n

FMOC \uae30\ubc18\uc758 \ud45c\uc900 \ubc29\ubc95\uc740 \uc120\ud0dd\uc801 \uc548\uc815\ud654 \ubc0f \uacb0\ud569 \uc81c\uac70\uc758 \ubc18\ubcf5\uc801\uc778 \uacfc\uc815\uc744 \uc5b4\ub5bb\uac8c \uc870\uc728\ud558\ub294\uc9c0\ub97c \ubcf4\uc5ec\uc90d\ub2c8\ub2e4.<\/p>\n

\ud2b9\uc815 \uce21\uc1c4\uc5d0 \ud544\uc694\ud55c \ubcf4\ud638 \uc720\ud615\uc740 \ub098\uba38\uc9c0 \uc544\ubbf8\ub178\uc0b0, \uc804\uccb4 \ub2e8\ubc31\uc9c8 \ubc0f \uc120\ud0dd\ub41c \ud569\uc131 \uc804\ub7b5\uc5d0 \ub530\ub77c \ub2ec\ub77c\uc9d1\ub2c8\ub2e4.<\/p>\n

\ub530\ub77c\uc11c \ubaa8\ub4e0 \uc544\ubbf8\ub178\uc0b0\uc774 \ub3d9\uc77c\ud55c \ubcf4\ud638\uae30\ub97c \ud544\uc694\ub85c\ud558\uac70\ub098 \ubaa8\ub4e0 \ud569\uc131 \uacfc\uc815\uc774 \ub3d9\uc77c\ud55c \ubcf4\ud638\uae30\ub97c \uc0ac\uc6a9\ud55c\ub2e4\ub294 \uc8fc\uc7a5\uc740 \uc62c\ubc14\ub974\uc9c0 \uc54a\ub2e4.<\/p>\n

\uc784\uc2dc \ubcf4\ud638 \uadf8\ub8f9\uc740 \ub610\ud55c \ud654\ud559\uc801 \uadf8\ub8f9\uacfc \uad6c\ubcc4\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4. \ud654\ud559\uc801 \uadf8\ub8f9\uc740 \ubbf8\ub9ac \uc900\ube44\ub41c \ud3a9\ud2f0\ub4dc \ub0b4\ubd80\uc5d0 \uc758\ub3c4\uc801\uc73c\ub85c \uc874\uc7ac\ud569\ub2c8\ub2e4.<\/p>\n

\uc608\ub97c \ub4e4\uc5b4, N-\ub05d \ub610\ub294 C-\ub05d\uc758 \uc544\ubbf8\ub4dc\uc5d0 \ub300\ud55c \uacc4\ud68d\ub41c \ubcc0\ud615\uc740 \ucd5c\uc885 \uad6c\uc870\uc758 \uc694\uc18c\uac00 \ub420 \uc218 \uc788\ub2e4.<\/p>\n

\ubc18\uba74, \ucd5c\uc885 \ubd84\uc790 \ub0b4\uc5d0 \uc6b0\uc5f0\ud788 \ub0a8\uc740 \uc784\uc2dc \ubcf4\ud638 \uadf8\ub8f9\uc740 \ubc14\ub78c\uc9c1\ud558\uc9c0 \uc54a\uc740 \uad6c\uc870\uc801 \ucc28\uc774\ub97c \uc758\ubbf8\ud560 \uac83\uc785\ub2c8\ub2e4.<\/p>\n

\uc6d0\uc704\uce58\uc131(orthogonality)\uc740 \ud654\ud559\uc801 \uc77c\uce58 \uc694\uac74\uc774\ub2e4.<\/h3>\n

\uc6d0\uc8fc \ubc29\ud5a5 \ubcf4\ud638\ub294 \uc120\ud0dd\ub41c \ubcf4\ud638 \uadf8\ub8f9\uc744 \uc81c\uac70\ud558\uc5ec \ub2e4\ub978 \ubcf4\uc548 \uc870\uce58\ub97c \ucda9\ubd84\ud788 \uc190\uc0c1 \uc5c6\uc774 \ub0a8\uae30\ub294 \uc804\ub7b5\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4.<\/p>\n

\uc774\ub294 \uc120\ud0dd\uc801\uc73c\ub85c \uc120\ud0dd\ub41c \ud569\uc131 \ub2e8\uacc4\uc5d0\uc11c \ub2e4\uc591\ud55c \ubc18\uc751 \uc9c0\uc810\uc744 \ubc1d\ud600\ub0b4\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub429\ub2c8\ub2e4.<\/p>\n

\uc6d0\uc8fc\uc131(orthogonality)\uc744 \ub2e8\uc21c\ud788 \uadf8 \uc81c\ud488\uc758 \ub77c\ubca8\uc5d0 \uae30\ub85d\ub41c \uac1c\ubcc4 \uc131\ubd84\ub4e4\uc758 \ud2b9\uc131\uc73c\ub85c \uc774\ud574\ud574\uc11c\ub294 \uc548 \ub429\ub2c8\ub2e4.<\/p>\n

\uadf8\uac83\uc740 \uacc4\ud68d\ub41c \ud654\ud559 \uc791\uc6a9\uc758 \uc804\uccb4 \uc21c\uc11c\uc758 \uc77c\uce58\uc131\uc744 \uc124\uba85\ud569\ub2c8\ub2e4.<\/p>\n

\ubcf4\ud638\ub9c9\uc758 \uc758\ub3c4\uc801\uc778 \uc81c\uac70\ub294 \uc131\uc7a5\ud558\ub294 \ud3a9\ud2f0\ub4dc\uc758 \ub2e4\ub978 \ubd80\ubd84\uc5d0 \ud5c8\uc6a9\ub418\uc9c0 \uc54a\ub294 \ubcc0\ud654\ub97c \uc720\ubc1c\ud558\uc9c0 \uc54a\uace0 \uc9c4\ud589\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\uc0c1\uc218 \ub2e8\uacc4\uc5d0\uc11c\uc758 \ud569\uc131\uc5d0\uc11c\ub294 \uc774 \uc77c\uce58\ub294 \uc9c0\uc9c0\uccb4-\uacb0\ud569\uccb4 \uc2dc\uc2a4\ud15c\uacfc \ube44\uc815\uc0c1\uc801\uc774\uac70\ub098 \ud2b9\ud788 \ud654\ud559\uc801\uc73c\ub85c \ubbfc\uac10\ud55c \uad6c\uc870 \ub2e8\uc704\ub3c4 \ud3ec\ud568\ud560 \uc218 \uc788\ub2e4.<\/p>\n

\uce21\uba74 \ubc0f \uad6c\uc870\uccb4 \ub9c1\uc744 \ubaa8\ub378 \ud53c\ud398\uc774\ub4dc\uc5d0\uc11c \ubcc0\ud615\uc2dc\ud0a8 \uc544\uc2a4\ud30c\ud2f0\ubbf8\ub4dc \uc0dd\uc131\uc5d0 \ub300\ud55c \uc5f0\uad6c\ub294 \ud53c\ud3ab\uc0b0\ubb3c \uc0dd\uc131\uc5d0 \ucc28\uc774\uac00 \uc788\uc74c\uc744 \ubcf4\uc5ec\uc8fc\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc774\ub294 \uc120\ud0dd\ud55c \uc548\uc804\uc7a5\uce58\uac00 \uba85\ubc31\ud55c \uce21\ubc29 \uc5f0\uc1c4 \ubc18\uc751\uc758 \ubc1c\uc0dd\uc5d0\ub9cc \uc601\ud5a5\uc744 \ubbf8\uce58\ub294 \uac83\uc774 \uc544\ub2c8\ub77c, \ub2e4\uc591\ud55c \ub2e4\ub978 \ubc18\uc751\ub4e4\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\uc74c\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4.<\/p>\n

\uadf8\ub4e4\uc740 \ub610\ud55c \ud569\uc131 \uacfc\uc815\uc5d0\uc11c \uc624\uc5fc\ubb3c \uc0dd\uc131 \uacbd\ub85c\ub97c \ubcc0\uacbd\ud560 \uc218 \uc788\ub2e4.<\/p>\n

\ubcf4\ud638 \uadf8\ub8f9\uc740 \ubaa8\ub4e0 \uc2dc\ud000\uc2a4\uac00 \ub3d9\uc77c\ud558\uac8c \ud589\ub3d9\ud558\uc9c0 \uc54a\ub294\ub2e4\ub294 \uac83\uc744 \uc758\ubbf8\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/h3>\n

\ub450 \uc5f0\uc18d\uccb4\uc5d0 \ub3d9\uc77c\ud55c \uc7a0\uc7ac\uc801\uc73c\ub85c \ubb38\uc81c\uac00 \ub420 \uc218 \uc788\ub294 \uc544\ubbf8\ub178\uc0b0\uc774 \ud3ec\ud568\ub418\uc5b4 \uc788\uc5b4\ub3c4, \uadf8\ub4e4\uc740 \ub3d9\uc77c\ud558\uac8c \ud589\ub3d9\ud560 \ud544\uc694\ub294 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc774\uc6c3\ud558\ub294 \ub2e4\ub978 \uc131\ubd84\ub4e4\uc740 \uacbd\uc7c1\uc801\uc778 \ubc18\uc751 \ubc1c\uc0dd \uac00\ub2a5\uc131\uc744 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\ub2e4.<\/p>\n

\uc544\uc2a4\ud30c\ub77c\uae34\uc744 \ud3ec\ud568\ud558\ub294 \ubaa8\ud615 \uc11c\uc5f4\ub4e4\uc758 \uccb4\uacc4\uc801\uc778 \uc5f0\uad6c\ub294 \uc774 \uc794\ub958\ubb3c \ub4a4\uc5d0 \uc788\ub294 \uc544\ubbf8\ub178\uc0b0\uc774 \uc2dc\ud5d8 \uc870\uac74\uc5d0\uc11c \uc544\uc2a4\ud30c\ub974\ud2f0\ubbf8\ub4dc \uad00\ub828 \uc81c\ud488\uc758 \uc0dd\uc131\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce5c\ub2e4\ub294 \uac83\uc744 \ubcf4\uc5ec\uc8fc\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

\uadf8\uac83\uc740 \uadf8\ub7ec\ud55c \uc8fc\uc81c\ub97c \ud3ec\ud568\ud558\ub294 \ubaa8\ub4e0 \uc2dc\ud000\uc2a4\uac00 \ubb38\uc81c\ub97c \uc57c\uae30\ud574\uc57c \ud55c\ub2e4\ub294 \uc758\ubbf8\ub294 \uc544\ub2d9\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \uadf8\uac83\uc740 \uc2dc\ud000\uc2a4 \ucee8\ud14d\uc2a4\ud2b8\uac00 \ubc29\ubc95 \uac1c\ubc1c \ubc0f \uc704\ud5d8 \ud3c9\uac00 \uc2dc \uace0\ub824\ub418\uc5b4\uc57c \ud568\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4.<\/p>\n

\ud55c \ubaa8\ub378\uc758 \ud398\ub2c8\ud2b8\uc774\ub4dc\uc5d0\uc11c \ud6a8\uacfc\uac00 \uc785\uc99d\ub41c \ubcf4\ud638 \uc804\ub7b5\uc740 \ub3d9\uc77c\ud55c \uc794\ub958\ubd84\uc744 \ud3ec\ud568\ud558\ub294 \ub2e4\ub978 \ud398\ub2c8\ud2b8\uc774\ub4dc\uc758 \ub3d9\uc77c\ud55c \ud589\ub3d9\uc744 \ubcf4\uc7a5\ud558\uc9c0\ub294 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc720\uc804\uc801 \ubcc0\uc774 \ubc0f \uae30\ud0c0 \ubd80\uc791\uc6a9<\/h2>\n

\ub808\uc774\uc2dc\ubbf8\uc544\uc158\uacfc \uc5d0\ud53c\uba54\ub9ac\uc81c\uc774\uc158\uc740 \ubd84\uc790\uc758 \uacf5\uac04\uc801 \uad6c\uc870\ub97c \ub2e4\ub8f9\ub2c8\ub2e4.<\/h3>\n

\ub9ce\uc740 \uc544\ubbf8\ub178\uc0b0 \uc794\ub958\ubb3c\uc5d0\ub294 \uc5ed\ubc29\ud5a5 \uc911\uc1c4 \uc911\uc2ec\uc774 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc774\ub7ec\ud55c \uc911\uc2ec\uccb4\uc758 \uad6c\uc131\ubcc0\ud654\ub294 \uc6d0\uc790 \uc870\uc131\uacfc \ubd84\uc790 \uc9c8\ub7c9\uc774 \ubcc0\ud558\uc9c0 \uc54a\ub294 \ud55c\ub3c4 \ub0b4\uc5d0\uc11c \uad6c\uc870\uc801\uc73c\ub85c \ub2e4\ub978 \ubd84\uc790\ub97c \uc0dd\uc131\ud560 \uc218 \uc788\ub2e4.<\/p>\n

\uc2e4\uc81c\ub85c, \ub77c\uc138\ub9c8\uc774\uc988\ub294 \uc5d0\ub09c\uc2dc\ubaa8\uc5b4\ub9ac\uc801 \ud48d\ubd80\ud654\ub97c \ub77c\uc138\ub9c8\uc774\uc2a4\ud2b8 \ud63c\ud569\ubb3c\ub85c \ud5a5\ud558\uac8c \ud558\ub294 \ubc29\ud5a5\uc73c\ub85c \uc783\uc5b4\ubc84\ub9ac\ub294 \uac83\uc744 \uc758\ubbf8\ud55c\ub2e4.<\/p>\n

\ub9ce\uc740 \uc5ed\ud615\uc131 \uc911\uc2ec\uc744 \ud3ec\ud568\ud558\ub294 \ud3a9\ud0c0\uc774\ub4dc\uc5d0\uc11c \ud55c \ud2b9\uc815 \uc911\uc2ec\uc758 \uad6c\uc131\uc774 \ub4a4\ubc14\ub00c\uba74 \uc77c\ubc18\uc801\uc73c\ub85c \uc5d0\ud53c\uba38\ub974, \uc989 \ub514\uc2a4\ud14c\ub85c\uc774\uc624\uba38\uc758 \ud615\ud0dc\uac00 \uc0dd\uae41\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \ub2e8\ubc31\uc9c8 \ud569\uc131\uc5d0 \uad00\ud55c \ubb38\ud5cc\uc5d0\uc11c \u201e\ub77c\uc138\ubbf8\uc9c0(racemization)\u201d\ub77c\ub294 \uc6a9\uc5b4\ub294 \uacb0\ud569 \ub610\ub294 \ub2e4\ub978 \ud569\uc131 \ub2e8\uacc4\uc5d0\uc11c \ubc1c\uc0dd\ud558\ub294 \uad6c\uc131 \ubcc0\ud654\uc5d0 \ub354 \uad11\ubc94\ud558\uac8c \uc801\uc6a9\ub429\ub2c8\ub2e4.<\/p>\n

\uc774 \ucc28\uc774\uc810\uc740 \uc911\uc694\ud569\ub2c8\ub2e4. \ub2e8\ubc31\uc9c8\uc758 \uc720\uc804\uc790\ub294 \ubd84\uc790 \ub0b4\uc5d0 \uc874\uc7ac\ud558\ub294 \uc6d0\uc790\ub4e4\ub9cc\uc73c\ub85c \uacb0\uc815\ub418\uc9c0 \uc54a\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4.<\/p>\n

\uadf8\ub4e4\uc758 \uacf5\uac04\uc801 \ubc30\uce58\ub3c4 \uc911\uc694\ud569\ub2c8\ub2e4.<\/p>\n

\ubaa8\ub4e0 \uc544\ubbf8\ub178\uc0b0 \uc794\ub958\ubb3c\uc740 \ub3d9\uc77c\ud55c \uc591\uc758 \uc2a4\ud14c\ub85c\ubbf9 \uc704\ud5d8\uc744 \ub3d9\ubc18\ud558\uc9c0\ub294 \uc54a\ub294\ub2e4.<\/p>\n

\uc608\ub97c \ub4e4\uc5b4 \uae00\ub9ac\uc2e0\uc5d0\ub294 \ub300\ubd80\ubd84\uc758 \uc544\ubbf8\ub178\uc0b0\uc5d0\uc11c \uc874\uc7ac\ud558\ub294 \uc77c\ubc18\uc801\uc778 \uc54c\ud30c-\uc54c\ud0ac \ud654\ud569\ubb3c\uc778 \uce58\ud658\uc131 \u03b1-\uc54c\ud0ac \uc6d0\uc790\uac00 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub2e4\ub978 \uc794\ub958\ubb3c\ub4e4\uc740 \uad6c\uc870\uc640 \ubc18\uc751 \ud658\uacbd\uc5d0 \ub530\ub77c \uad6c\uc131\ubcc0\ud654\uc5d0 \ub354 \ubbfc\uac10\ud569\ub2c8\ub2e4.<\/p>\n

\uc815\uc0c1 \uc9c8\ub7c9\uc740 \uc798\ubabb\ub41c \uc785\uc790 \uad6c\uc870\uc640 \ud568\uaed8 \ub098\ud0c0\ub0a0 \uc218 \uc788\ub2e4.<\/h3>\n

\ud3a9\ud0c0\uc774\ub4dc \uc5d0\ud53c\uba54\ub9ac\uc5b8\uc740 \ud45c\uc801 \ud3a9\ud0c0\uc774\ub4dc\uc640 \uc815\ud655\ud788 \ub3d9\uc77c\ud55c \ubd84\uc790\ub7c9\uc744 \uac00\uc9c8 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub530\ub77c\uc11c \uc9c8\ub7c9\ubd84\uc11d\uae30\ub97c \uc0ac\uc6a9\ud558\uc5ec \uc608\uc0c1\ub41c \uc9c8\ub7c9\uc744 \uad00\ucc30\ud558\ub294 \uac83\ub9cc\uc73c\ub85c \ubaa8\ub4e0 \uc544\ubbf8\ub178\uc0b0 \uc794\ub958\ubb3c\uc774 \uc758\ub3c4\ub41c \uc785\uc790\ud615 \uad6c\uc131\uc744 \uc720\uc9c0\ud558\uace0 \uc788\ub294 \uac83\uc740 \uc544\ub2c8\ub2e4.<\/p>\n

\uc0c9\uc18c\ud3ec\uc9c0\uba3c\ud2b8 \uc5f0\uad6c\ub294 \ubcf4\ud638\ub41c \uc774\uc911\uc6d0\uc790\uc131 \ub2e8\ubc31\uc9c8\ub4e4\uc744 \ubd84\ub9ac\ud558\uace0 \uc774\ub7ec\ud55c \ubd84\ub9ac \uacb0\uacfc\ub97c \uc0c1\ud638\uad00\ub828\ub41c \ud654\ud559\uc801 \uacb0\ud569\uc5d0 \ub530\ub978 \ud3b8\ud5a5 \ubcc0\ud654 \ubd84\uc11d\uc5d0 \uc774\uc6a9\ud560 \uc218 \uc788\ub3c4\ub85d \ud574\uc900\ub2e4.<\/p>\n

\ubd84\uc790\ub9c8\ub2e4 \ub530\ub77c \ub2ec\ub77c\uc9c0\ub294 \uc801\uc808\ud55c \ud3b8\ud5a5 \ud3c9\uac00\uc5d0\ub294 \uc801\uc808\ud55c \ud06c\ub85c\ub9c8\ud1a0\uadf8\ub798\ud53c \ubc29\ubc95, \uae30\uc900 \ud654\ud569\ubb3c, \ub514\uc5b4\ubc14\ud2f0\uc9c0 \uc804\ub7b5 \ub610\ub294 \uc911\uc694\ud55c \uad6c\uc870\ub97c \uad6c\ubcc4\ud560 \uc218 \uc788\ub294 \ub2e4\ub978 \ubd84\uc11d \ubc29\ubc95\uc744 \ud544\uc694\ub85c \ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uac1c\ubcc4 \ubd84\uc11d \uc5f0\uad6c\uc5d0\uc11c\ub294 \uc544\ubbf8\ub178\uc0b0\uc774 \uace0\uccb4 \ub9e4\uccb4\uc5d0 \uacb0\ud569\ub418\ub294 \uacfc\uc815\uc5d0\uc11c \ubc1c\uc0dd\ud558\ub294 \ub3d9\uc801 \uc131\uc9c8 \ubcc0\ud654\ub3c4 \ubd84\uc11d\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc774\ub294 \ub2e4\uc74c \uc911\uc694\ud55c \uacb0\ub860\uc73c\ub85c \uc774\uc5b4\uc9d1\ub2c8\ub2e4: \uc644\uc131\ub41c \ud3a9\ud2f0\ub4dc\uc5d0\uc11c \uac80\ucd9c\ub41c \uc624\uc5fc\uc740 \ub9c8\uc9c0\ub9c9 \uacb0\ud569 \ubc18\uc751\uc5d0\uc11c \uc720\ub798\ud574\uc57c \ud560 \ud544\uc694\uac00 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n

\uadf8\uac83\uc740 \uc774\uc804 \ub2e8\uacc4\uc5d0\uc11c \uc0dd\uaca8\ub0a0 \uc218 \uc788\uc5c8\uace0, \uc774\ud6c4\uc758 \ud569\uc131 \ub2e8\uacc4\ub4e4\uc5d0\uc11c \uacc4\uc18d \uc874\uc7ac\ud560 \uc218 \uc788\uc5c8\ub2e4.<\/p>\n

\uc544\uc2a4\ud30c\ud2f0\ubbf8\ub4dc\uc758 \uc0dd\uc131\uc740 \ubcc4\uac1c\uc758 \ubb38\uc81c\uc785\ub2c8\ub2e4.<\/h3>\n

\uc544\uc2a4\ud30c\ub974\ud2f0\ubbf8\ub4dc\uc758 \uc0dd\uc131\uc740 \uc544\uc2a4\ud30c\ub77c\uae34\uc0b0\uc744 \ud568\uc720\ud558\ub294 \ucde8\uc57d\ud55c \ud3a9\ud2f0\ub4dc \uc11c\uc5f4\uacfc \uad00\ub828\ub41c \ud2b9\uc218\ud55c \ubd80\uc791\uc6a9 \ubc18\uc751 \uacbd\ub85c\uc785\ub2c8\ub2e4.<\/p>\n

\uc774 \uacfc\uc815\uc740 \uc8fc\uae30\uc801\uc73c\ub85c \uc0dd\uc131\ub418\ub294 \uc911\uac04 \uc81c\ud488\uc744 \uc0dd\uc131\ud558\ub294 \uac83\uc744 \ud3ec\ud568\ud558\uba70, \uc774 \uc81c\ud488\ub4e4\uc740 \uc774\ud6c4 \ub2e4\uc591\ud55c \uad00\ub828 \uad6c\uc870\ubb3c\ub85c \ubc1c\uc804\ud560 \uc218 \uc788\ub2e4.<\/p>\n

\uadf8\ub4e4\uc740 \ub2e8\ubc31\uc9c8 \uad6c\uc870\uc758 \ubcc0\ud615\ub41c \uacb0\ud569\uacfc \ub3d9\uc801 \uc591\uc790\uc801 \ubcc0\ud615\uc744 \ud3ec\ud568\ud560 \uc218 \uc788\ub2e4.<\/p>\n

\ub530\ub77c\uc11c \uc544\uc2a4\ud30c\ud2f0\ubbf8\ub4dc\uc758 \ubc1c\uc0dd\uc744 \ub2e8\uc21c\ud788 \uc644\uc804 \uacb0\ud569\ub418\uc9c0 \uc54a\uc740 \ub2e4\ub978 \uc774\ub984\uc73c\ub85c \uc124\uba85\ud574\uc11c\ub294 \uc548 \ub429\ub2c8\ub2e4.<\/p>\n

\ud3a9\ud0c0\uc774\ub4dc \uc0ac\uc2ac\uc5d0\ub294 \uc774\ubbf8 \uc801\uc808\ud55c \uc544\ubbf8\ub178\uc0b0 \uc794\ub958\ubb3c\ub4e4\uc774 \ud3ec\ud568\ub420 \uc218 \uc788\uc73c\uba70, \uc774\ud6c4\uc758 \ubd80\uc791\uc6a9 \ubc18\uc751\uc740 \uadf8 \uad6c\uc870\uc758 \uc77c\ubd80\ub97c \ubcc0\ud615\uc2dc\ud0ac \uc218 \uc788\ub2e4.<\/p>\n

\uc2e4\ud5d8\uc801 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc774\ub7ec\ud55c \uacfc\uc815\uc5d0\ub294 \ubcf4\ud638 \uadf8\ub8f9 \uc81c\uac70\uc640 \uad00\ub828\ub41c \uc804\ub7b5, \uc778\uc811\ud55c \uc794\ub958\ubb3c \ubc0f \ubc18\ubcf5\uc801\uc778 \uc870\uac74\ub4e4\uc774 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\ub2e4.<\/p>\n

\uc774\ub7ec\ud55c \uad6c\ubcc4\uc740 \ud569\uc131\uc5d0\uc11c \ubc1c\uc0dd\ud558\ub294 \ubb38\uc81c\ub4e4\uc744 \ud574\uc11d\ud560 \ub54c \ud2b9\ud788 \uc911\uc694\ud569\ub2c8\ub2e4.<\/p>\n

\uc5f0\uacb0\ubb3c\uc758 \ubc18\ubcf5\uc801\uc778 \uacb0\ud569 \ub610\ub294 \ub354 \ub9ce\uc740 \uacb0\ud569 \ucd09\ub9e4\uc81c\ub97c \ucca8\uac00\ud558\ub294 \uac83\ub9cc\uc73c\ub85c\ub294 \uc644\uc804\ud788 \ub2e4\ub978 \ud654\ud559 \uacbd\ub85c\ub85c \uc778\ud574 \ubc1c\uc0dd\ud55c \uc624\uc5fc\uc744 \uc790\ub3d9\uc73c\ub85c \ud574\uacb0\ud560 \uc218 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n

\ubd80\ubd84\uc801\uc778 \ubc18\uc751\uc740 \ub2e4\ub978 \uc885\ub958\uc758 \ubb38\uc81c\ub97c \uc57c\uae30\ud569\ub2c8\ub2e4.<\/h3>\n

\ubd80\uc801\uc808\ud55c \uacb0\ud569\uc740 \ubcc4\ub3c4\uc758 \uc624\uc5fc\ubb3c\uc9c8 \ubc94\uc8fc\ub97c \uc0dd\uc131\ud569\ub2c8\ub2e4.<\/p>\n

\ub9cc\uc57d \uc2e4\ub9ac\ucf58\uacfc \uad00\ub828\ub41c \ud55c \ub9c1\ucee4\uac00 \uacc4\ud68d\ub41c \uc544\ubbf8\ub178\uc0b0\uc744 \uc218\uc6a9\ud558\uc9c0 \ubabb\ud558\uace0 \ub098\uc911\uc5d0 \ubc18\ubcf5\ub418\ub294 \uacfc\uc815\uc5d0\uc11c \uc815\uc0c1\uc801\uc73c\ub85c \ubc18\uc751\ud55c\ub2e4\uba74, \uc0dd\uc131\ub41c \ud3a9\ud2f0\ub4dc\ub294 \uc774 \uc794\ub958\ubd84\uc744 \uc81c\uac70\ud560 \uc218 \uc788\ub2e4.<\/p>\n

\uc774\ub7ec\ud55c \ubd84\uc790\uccb4\ub97c \uc77c\ubc18\uc801\uc73c\ub85c \ub514\ub808\uc2dc\uc5b8\uc2a4 \uc11c\uc5f4\uc774\ub77c\uace0 \ud569\ub2c8\ub2e4.<\/p>\n

\ub2e4\ub978 \uccb4\uc778\uc740 \uacc4\uc18d \ub298\uc5b4\ub098\uc9c0 \uc54a\uace0 \ub2e8\ucd95\ub420 \uc218 \uc788\ub2e4.<\/p>\n

\uc774\ub4e4 \uc81c\ud488\uc740 \uae30\ubcf8\uc801\uc73c\ub85c \uc5d0\ud53c\uba38\uc640\ub294 \ub2e4\ub985\ub2c8\ub2e4.<\/p>\n

\uc5d0\ud53c\uba38\ub294 \uc62c\ubc14\ub978 \uc544\ubbf8\ub178\uc0b0 \uc11c\uc5f4\uacfc \ucd1d\ud569\ud615\uc2dd\uc744 \uac00\uc9c8 \uc218 \uc788\uc9c0\ub9cc, \ud558\ub098\uc758 \uc911\uc2ec\uc758 \ubd88\uc644\uc804\ud55c \uc785\uc790\ud615\uc131\uc744 \uac00\uc9c8 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ubc18\uba74, \ud53c\uc5d0\ufffd\ud2f0\ub514\uc62c\uc740 \ub2e4\ub978 \uc11c\uc5f4\uc774\ub098 \uae38\uc774\uac00 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc77c\ubd80 \ud569\uc131 \uc804\ub7b5\uc740 \ud2b9\uc815 \ubc18\uc751\uc774 \uc5c6\ub294 \uc5fc\uae30\ub4e4\uc758 \uc5f0\uc7a5\uc744 \ubc29\uc9c0\ud558\uae30 \uc704\ud574 '\ucea1\ud551(capping)'\uc774\ub77c\ub294 \uae30\uc220\uc744 \uc0ac\uc6a9\ud569\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \ucea1\ud551\uc740 \uc798\ubabb\ub41c \uc0ac\uc2ac\uc744 \ubcf5\uad6c\ud558\uc9c0 \uc54a\uc73c\uba70, \uc774\ub97c \ucd5c\uc885 \ub2e8\ubc31\uc9c8\ub85c \ubcc0\ud658\ud558\uc9c0\ub3c4 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n

\uadf8\uac83\uc740 \ub2e8\uc9c0 \uadf8\uac00 \ub2e4\uc74c \ub2e8\uacc4\uc5d0\uc11c \ubcf4\uc5ec\uc8fc\ub294 \ud589\ub3d9\uc744 \ubcc0\uacbd\ud560 \ubfd0\uc774\ub2e4.<\/p>\n

\ub530\ub77c\uc11c \ud569\uc131 \uacfc\uc815\uc5d0\uc11c \uc5bb\uc5b4\uc9c4 \uace0\uccb4 \ud63c\ud569\ubb3c\uc5d0\ub294 \uc5ec\ub7ec \uac00\uc9c0 \ub2e4\ub978 \uba54\ucee4\ub2c8\uc998\uc5d0 \uc758\ud574 \uc0dd\uc131\ub41c \uc81c\ud488\ub4e4\uc774 \ud3ec\ud568\ub420 \uc218 \uc788\ub2e4.<\/p>\n

\ucd1d \uc0dd\uc0b0\uc131 \uac12 \ud558\ub098\ub85c\ub294 \uc5b4\ub5a4 \uc624\uc5fc \uba54\ucee4\ub2c8\uc998\uc774 \ucd5c\uc885 \uacb0\uacfc\ub97c \ucd08\ub798\ud588\ub294\uc9c0 \ud655\uc778\ud560 \uc218 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc628\ub3c4\uc640 \uacf5\uc815 \uc870\uac74\uc740 \uc18d\ub3c4\uc640 \ud488\uc9c8 \uc0ac\uc774\uc758 \uade0\ud615\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4.<\/h3>\n

\uc628\ub3c4 \uc0c1\uc2b9 \ub610\ub294 \uae30\ud0c0 \ud569\uc131 \ucd09\uc9c4 \ubc29\ubc95\uc740 \uc6d0\ud558\ub294 \ubc18\uc751 \uc18d\ub3c4\ub97c \ub192\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \ub3d9\uc2dc\uc5d0 \ubd80\uc791\uc6a9\uc758 \ubc1c\uc0dd\uc744 \uac00\uc18d\ud654\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

SPPS \uae30\ubc18 \ub9c8\uc774\ud06c\ub85c\ud30c \uc5f0\uad6c\ub294 \ubaa8\ub378 \uc2dc\uc2a4\ud15c\uc5d0\uc11c \ub808\uc2dc\uba54\uc774\uc9d5\uacfc \uc544\uc2a4\ud30c\ub974\ud2f0\ubbf8\ub4dc \uc0dd\uc131 \uacfc\uc815\uc744 \ubd84\uc11d\ud588\uc73c\uba70, \uc0ac\uc6a9\ub41c \uc870\uac74\uc5d0\uc11c \uc794\ub958\ubb3c\uc758 \uc885\ub958\uc5d0 \ub530\ub978 \ubbfc\uac10\ub3c4\ub97c \ud655\uc778\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc774\ub294 \ub09c\ubc29\uc774 \ub2e8\ubc31\uc9c8 \ud569\uc131\uc5d0 \uc788\uc5b4 \ubcf8\uc9c8\uc801\uc73c\ub85c \uc798\ubabb\ub41c \uac83\uc774\ub77c\ub294 \uac83\uc744 \uc758\ubbf8\ud558\uc9c0\ub294 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub610\ud55c, \ub354 \ub0ae\uc740 \uc628\ub3c4\uac00 \ud56d\uc0c1 \ub354 \ub098\uc740 \uac83\uc740 \uc544\ub2d9\ub2c8\ub2e4.<\/p>\n

\uac00\uc7a5 \uc911\uc694\ud55c \uc6d0\uce59\uc740 \ub2e4\uc74c\uacfc \uac19\uc2b5\ub2c8\ub2e4: \ud504\ub85c\uc138\uc2a4\uc758 \uc18d\ub3c4\uc640 \ud654\ud559\uc801 \ud488\uc9c8\uc740 \ub3d9\uc2dc\uc5d0 \ud3c9\uac00\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\ub354 \ub192\uc740 \uc628\ub3c4, \ub354 \uae34 \ub178\ucd9c \uc2dc\uac04 \ub610\ub294 \ubc18\ubcf5\uc801\uc778 \ucc98\ub9ac\ub294 \uc6d0\ud558\ub294 \uacb0\ud569 \uc0dd\uc131\uc5d0 \ubfd0\ub9cc \uc544\ub2c8\ub77c \uacbd\uc7c1 \ubc18\uc751\uc5d0\ub3c4 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\ub2e4.<\/p>\n

\ub530\ub77c\uc11c \uc801\uc808\ud55c \ud0c0\ud611\uc740 \ud2b9\uc815 \uc2dc\ud000\uc2a4\uc5d0 \ub300\ud574 \uc2e4\ud5d8\uc801\uc73c\ub85c \ud3c9\uac00\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\uacb0\uacfc\ubb3c\uc5d0 \ub300\ud55c \uc218\uc815\uc740 \ub610\ud55c \uc9c1\uc811 \uacb0\ud569\uc774 \ub05d\ub09c \ud6c4\uc5d0\ub3c4 \ubc1c\uc0dd\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ud398\uc774\uc2a4\ud2b8\uc5d0\uc11c \ud53c\ud2f0\ub4dc\ub97c \ubd84\ub9ac\ud558\ub294 \uacfc\uc815\uc5d0\uc11c \ub2e4\uc591\ud55c \uc138\ub77c\uace4\uc744 \ube44\uad50\ud55c \uc5f0\uad6c\uc5d0\uc11c\ub294 \uc11c\ub85c \ub2e4\ub978 \uc624\uc5fc\ubb3c\uc9c8 \ud504\ub85c\ud30c\uc77c\uc744 \uad00\ucc30\ud588\ub2e4.<\/p>\n

\uc774\ub294 \ucd5c\uc885 \uc624\uc5fc\uc774 \uacb0\ud569 \ubc18\uc751\uc5d0 \uc790\ub3d9\uc801\uc73c\ub85c \uae30\uc778\ud55c\ub2e4\uace0 \ubcf4\uae30\ub294 \uc5b4\ub835\ub2e4\ub294 \uac83\uc744 \uc0c1\uae30\uc2dc\ucf1c \uc900\ub2e4.<\/p>\n

\ud3a9\ud0c0\uc774\ub4dc \ud569\uc131\uc740 \ub2e4\ub2e8\uacc4 \uacfc\uc815\uc774\uba70, \ub098\uc911\uc5d0 \ud574\uc81c, \ubd84\ub9ac \ubc0f \ucd94\uac00 \uac00\uacf5\uc740 \uc774\uc804\uc5d0\ub294 \uc62c\ubc14\ub974\uac8c \uad6c\uc131\ub41c \ubb3c\uc9c8\uc744 \ubcc0\uacbd\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc5f0\uacb0 \ud6a8\uc728\uc131\uc740 \uc5b4\ub5bb\uac8c \ud3c9\uac00\ub429\ub2c8\uae4c?<\/h2>\n

\uacfc\uc815\uc5d0\uc11c \uc218\ud589\ub418\ub294 \ud14c\uc2a4\ud2b8\ub294 \ud2b9\uc815 \uc9c8\ubb38\uc5d0\ub9cc \ub2f5\ud569\ub2c8\ub2e4.<\/h3>\n

\uc0c1\uc218 \ub2e8\uacc4\uc5d0\uc11c\uc758 \ud569\uc131 \uacfc\uc815\uc5d0\uc11c \ub2e4\ub978 \uc720\ud6a8 \uc544\ubbf8\ub178 \uadf8\ub8f9\uc744 \uac80\ucd9c\ud558\ub294 \ud14c\uc2a4\ud2b8\ub294 \uc544\uc2e4\ud654 \ub2e8\uacc4\uac00 \uc644\uc804\ud558\uac8c \uc9c4\ud589\ub418\uc5c8\ub294\uc9c0 \uc5ec\ubd80\ub97c \ud3c9\uac00\ud558\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7f0 \ud14c\uc2a4\ud2b8\ub4e4\uc740 \ub9e4\uc6b0 \uc720\uc6a9\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \uadf8\ub4e4\uc758 \ud574\uc11d\uc740 \uc2e4\uc81c\ub85c \ud574\ub2f9 \ubc29\ubc95\uc774 \uc81c\uacf5\ud558\ub294 \ud654\ud559\uc801 \uc9c8\ubb38\uc5d0\ub9cc \uad6d\ud55c\ub418\uc5b4\uc57c \ud55c\ub2e4.<\/p>\n

\ubd84\uc11d \ubc29\ubc95\uacfc \uc544\ubbf8\ub178\uc0b0 \uc885\ub958\uc5d0 \ub530\ub77c \uc0c9 \ubcc0\ud654\ub97c \uae30\ubc18\uc73c\ub85c \ud55c \uac80\uc0ac\ub294 \ub2e4\uc591\ud55c \uc544\ubbf8\ub178\uc0b0\uc5d0 \ub300\ud574 \uc11c\ub85c \ub2e4\ub978 \ubc29\uc2dd\uc73c\ub85c \ubc18\uc751\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub610\ud55c \uac80\uc0ac\ub41c \uc7a5\uc18c\uc758 \uc811\uadfc\uc131\ub3c4 \uc911\uc694\ud569\ub2c8\ub2e4.<\/p>\n

\uc2dc\ud5d8\ubb3c\uc9c8\uc774 \ubb3c\ub9ac\uc801\uc73c\ub85c \uc811\uadfc\ud558\uae30 \uc5b4\ub824\uc6b4 \ubc18\uc751\uc131 \uc544\ubbf8\ub178\uadf8\ub8f9\uc740, \ud569\uc131\ud654 \ubc18\uc751\uc744 \uc815\uc0c1\uc801\uc73c\ub85c \uac70\uce5c \ub3d9\uc77c\ud55c \uc544\ubbf8\ub178\uadf8\ub8f9\uacfc \ub3d9\uc77c\ud558\uc9c0 \uc54a\ub2e4 \u2014 \uc774\ub4e4 \uc0c1\ud669\uc744 \uba85\ud655\ud558\uac8c \uad6c\ubcc4\ud560 \uc218 \uc5c6\ub294 \uacbd\uc6b0\uc5d0\ub3c4 \ub9c8\ucc2c\uac00\uc9c0\ub2e4.<\/p>\n

\ub530\ub77c\uc11c \uc81c\ud55c \uc0ac\ud56d\uc5d0\ub294 \uc7ac\ud65c\uc131\ud654 \uacf5\uac04\uc758 \uc720\ud6a8\uc131, \uac80\uc0ac\uc758 \ubbfc\uac10\ub3c4, \ud654\ud559\uc801 \uac04\uc12d, \uadf8\ub9ac\uace0 \ud0d0\uc9c0\ub41c \uae30\ub2a5\uad70 \uc720\ud615\uc774 \ud3ec\ud568\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc2dc\ud5d8 \uacb0\uacfc\uc758 \ubd80\uc815\uc801\uc778 \uacb0\uacfc\ub294 \uc804\uccb4 \ud3a9\ud2f0\ub4dc\uac00 \uc62c\ubc14\ub978 \uc11c\uc5f4, \uc785\uccb4\uad6c\uc870 \ubc0f \uc21c\ub3c4\ub97c \uac16\ucd94\uace0 \uc788\ub2e4\ub294 \uac83\uc744 \uc790\ub3d9\uc73c\ub85c \uc99d\uba85\ud558\ub294 \uac83\uc73c\ub85c \ud574\uc11d\ud574\uc11c\ub294 \uc548 \ub429\ub2c8\ub2e4.<\/p>\n

\ud504\ub85c\uc138\uc2a4\uc758 \ubaa8\ub2c8\ud130\ub9c1\uc740 \uadf8 \uacb0\uacfc\uac00 \uc2e4\uc81c \ud3a9\ud2f0\ub4dc \uc81c\ud488 \ubd84\uc11d\uacfc \ub354\ubd88\uc5b4 \ube44\uad50\ub420 \uc218 \uc788\ub294 \uacbd\uc6b0\uc5d0 \uac00\uc7a5 \uac00\uce58\uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc0c9\uc804\ubc95\uc740 \ubd84\ub9ac\ud558\uace0 \ubd84\uad11\ubc95\uc740 \uc131\ubd84\uc744 \uaddc\uba85\ud558\ub294 \ub370 \ub3c4\uc6c0\uc744 \uc90d\ub2c8\ub2e4.<\/h3>\n

\uc0c9\uc804\ubc95 \ubc0f \ubd84\uc790 \ubd84\uc11d\uc740 \uc11c\ub85c \ubcf4\uc644\uc801\uc778 \uc815\ubcf4\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4.<\/p>\n

\uc0c9\uc804\ubc95\uc740 \uc2dc\ub8cc\uc758 \uc131\ubd84\uc744 \ubd84\ub9ac\ud558\uace0 \uc5ec\ub7ec \uac1c\uc758 \uac80\ucd9c \uac00\ub2a5\ud55c \uc131\ubd84\uc744 \ud655\uc778\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub9c8\uc2a4 \uc2a4\ud399\ud2b8\ub7fc \ubd84\uc11d\uc740 \ubd84\uc790 \uc9c8\ub7c9 \uc815\ubcf4\ub97c \uc81c\uacf5\ud558\uc5ec \ud2b9\uc131 \ubd84\uc11d\uc774\ub098 \uac1c\ubcc4 \uc131\ubd84\ub4e4\uc758 \uacb0\ud569\uc744 \ub3c4\uc6b8 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub450 \uac00\uc9c0 \uae30\uc220\uc744 \uacb0\ud569\ud55c \uc5f0\uad6c\ub294 \ub2e8\ubc31\uc9c8 \ud569\uc131\uc758 \uc6d0\ub8cc \uc81c\ud488\uc744 \uace0\uccb4 \uc0c1\ud0dc\uc5d0\uc11c \ubd84\uc11d\ud558\uace0 \uadf8\ub4e4\uc758 \uc815\uccb4\uc131 \ubc0f \ubcf4\ud638 \uadf8\ub8f9 \uc81c\uac70 \uc815\ub3c4\uc5d0 \ub300\ud55c \uc815\ubcf4\ub97c \uc5bb\uc744 \uc218 \uc788\ub3c4\ub85d \ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub450 \uac00\uc9c0 \ubc29\ubc95\uc744 \uc870\ud569\ud558\uba74 \uc77c\ubc18\uc801\uc73c\ub85c \ubaa8\ub4e0 \ud06c\ub85c\ub9c8\ud1a0\uadf8\ub798\ud53c \uc810\uc774 \uc774\ubbf8 \ud655\uc778\ub418\uc5c8\uac70\ub098, \ub610\ub294 \ubaa8\ub4e0 \uac80\ucd9c\ub41c \ubd84\uc790\uac00 \uc21c\uc218\ud558\uace0 \uad6c\uc870\uc801\uc73c\ub85c \uc644\uc804\ud55c \ud504\ub799\uc158\uc5d0 \ud574\ub2f9\ud55c\ub2e4\ub294 \uac00\uc815\ubcf4\ub2e4 \ub354 \ub9ce\uc740 \uc815\ubcf4\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \uc5ec\uc804\ud788 \uc81c\ud55c \uc0ac\ud56d\uc774 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub2e4\uc591\ud55c \uc131\ubd84\ub4e4\uc774 \ub3d9\uc9c8\ud654\ub420 \uc218 \uc788\uc73c\uba70, \uc989 \ud06c\ub85c\ub9c8\ud1a0\uadf8\ub798\ud53c\uc801 \ubd84\ub9ac\uc5d0\uc11c \uc644\uc804\ud788 \ubd84\ub9ac\ub418\uc9c0 \uc54a\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uac1c\ubcc4 \ubb3c\uc9c8\uc740 \ub610\ud55c \ub2e4\uc591\ud55c \uac10\uc9c0\uae30 \ubc18\uc751\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uad6c\uc870 \uc774\uc131\uc9c8\uccb4 \ubc0f \uc0bc\uc704\uc131\uc9c8\uccb4\ub294 \ucd94\uac00 \ubd84\uc11d \ubc29\ubc95\uc744 \uc801\uc6a9\ud574\uc57c \ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uac19\uc740 \uc774\uc720\ub85c \ub2e8\uc9c0 \ud3a9\ud0c0\uc774\ub4dc\uac00 HPLC \ubc29\ubc95\uc744 \ud1b5\ud574 \uac80\uc0ac\ub418\uc5c8\ub2e4\ub294 \uc0ac\uc2e4\ub9cc\uc73c\ub85c \ubaa8\ub4e0 \uc911\uc694\ud55c \uc624\uc5fc \ubb3c\uc9c8\uc744 \ubd84\ub9ac\ud588\ub2e4\uace0 \ub2e8\uc815\ud560 \uc218\ub294 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n

\ud2b9\uc815 HPLC \ubc29\ubc95\uc744 \ud65c\uc6a9\ud558\ub294 \ud6a8\uacfc\ub294 \uc2e4\uc81c\ub85c \uc5bb\uc5b4\uc9c4 \ubd84\ub9ac\ub7c9\uacfc \uadf8\uc5d0 \ub530\ub77c \ub2f5\ubcc0\ud574\uc57c \ud560 \ubd84\uc11d \uc9c8\ubb38\uc5d0 \ub530\ub77c \ub2ec\ub77c\uc9d1\ub2c8\ub2e4.<\/p>\n

\uacb0\uacfc\ub97c \uc5b4\ub5bb\uac8c \uacc4\uc0b0\ud588\ub294\uc9c0 \uc124\uba85\ud574\uc57c \ud569\ub2c8\ub2e4.<\/h3>\n

\ud3a9\ud0c0\uc774\ub4dc \uacb0\ud569\uc5d0 \ub300\ud55c \ubc31\ubd84\uc728 \uac12\uc740 \uc5ec\ub7ec \uac00\uc9c0 \uc644\uc804\ud788 \ub2e4\ub978 \uc758\ubbf8\ub97c \uac00\uc9c8 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc774\ub294 \ucd9c\ucc98 \ubb3c\uc9c8\uc758 \ubcc0\ud615, \uc0c9\uc18c \ubd84\uc11d\uae30\uc758 \uc0c1\ub300\uc801 \ud45c\uba74\uc801, \ucd5c\uc885 \uc81c\ud488\uc758 \uce21\uc815\ub41c \ud568\ub7c9, \uc6d0\ub8cc\uc758 \uc0dd\uc0b0\uc131 \ub610\ub294 \ubd84\ub9ac\ub41c \uc0dd\uc0b0\uc131 \ub4f1\uc744 \uc758\ubbf8\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc790\uccb4\uc801\uc73c\ub85c \uc5b4\ub5a4 \uac83\uc744 \uc758\ubbf8\ud558\ub294\uc9c0 \uc124\uba85 \uc5c6\uc774 \uadf8 \uc22b\uc790\ub97c \uc81c\uc2dc\ud558\ub294 \uac83\uc740, \ub530\ub77c\uc11c \ud070 \uc138\ubc00\ud568\uc744 \ubcf4\uc5ec\uc8fc\ub294 \uc624\ud574\ub97c \ubd88\ub7ec\uc77c\uc73c\ud0ac \uc218 \uc788\ub2e4.<\/p>\n

\uc2e0\ube59\uc131 \uc788\ub294 \ube44\uad50\ub294 \ubd84\uc11d \ub300\uc0c1 \ubb3c\uc9c8, \ubd84\uc11d \ub2e8\uacc4, \uc0ac\uc6a9\ub41c \ubd84\uc11d \ubc29\ubc95, \uc2dc\ub8cc \ucc44\ucde8 \uc2dc\uc810, \uadf8\ub9ac\uace0 \uac80\uc0ac\ub41c \uc624\uc5fc\ubb3c\uc9c8\uc758 \uc885\ub958\ub97c \uaddc\uc815\ud574\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\ub2e4\uc2dc \ubc18\ubcf5\ub41c \uc5f0\uad00\uc744 \uc0ac\uc6a9\ud55c \uacbd\uc6b0\ub3c4 \uace0\ub824\ud574\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\ub450 \ubc88\uc758 \uacb0\ud569 \uc218\uc220\uc758 \ucd5c\uc885 \uacb0\uacfc\uac00 \uccab \ubc18\uc751 \ub2f9\uc2dc \uc77c\uc5b4\ub09c \uc77c\ub4e4\uc744 \ubc18\uc601\ud560 \ud544\uc694\ub294 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n

\ubd84\uc11d \ubc29\ubc95\uc758 \uac80\ucd9c \ud55c\uacc4\uc5d0\ub3c4 \uc720\uc0ac\ud55c \uc8fc\uc758\uac00 \ud544\uc694\ud569\ub2c8\ub2e4.<\/p>\n

\u201e\ubc1c\uacac\ub418\uc9c0 \uc54a\uc74c\u201d\uc774\ub77c\ub294 \uc9c4\uc220\uc740 \ud574\ub2f9 \ubb3c\uc9c8\uc774 \ud2b9\uc815 \uc870\uac74 \ubc0f \uc801\uc6a9\ub41c \ubc29\ubc95\uc758 \uc81c\ud55c \ud558\uc5d0\uc11c \uac80\ucd9c\ub418\uc9c0 \uc54a\uc558\uc74c\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4.<\/p>\n

\uc774\ub294 \ub370\uc774\ud130\uc5d0 \ub300\ud55c \uc624\uc5fc\uc774 \uc804\ud600 \uc874\uc7ac\ud558\uc9c0 \uc54a\ub294\ub2e4\ub294 \uc808\ub300\uc801\uc778 \uc8fc\uc7a5\uc744 \uc790\ub3d9\uc73c\ub85c \ubc1b\uc544\ub4e4\uc77c \uc218 \uc788\ub294 \uac83\uc774 \uc544\ub2d9\ub2c8\ub2e4.<\/p>\n

\ucd09\ub9e4\ubb3c\uc5d0 \ub300\ud55c \ub370\uc774\ud130\ub294 \ub2e8\uc21c\ud55c \ubaa8\ub378\ubcf4\ub2e4 \ub354 \ub9ce\uc740 \uac83\uc744 \ud3ec\ud568\ud574\uc57c \ud569\ub2c8\ub2e4.<\/h3>\n

\uac04\ub2e8\ud55c \ubaa8\ub378 \ubc18\uc751\uc5d0\uc11c \ud0c1\uc6d4\ud55c \ud6a8\uacfc\ub97c \ubcf4\uc774\ub294 \uc811\ud569 \ucd09\ub9e4\ub294, \uc2a4\ud14c\ub85c\uc2dc\ub4dc \ubc00\ub3c4\uac00 \ub192\uc740 \ub300\ub7c9 \uc544\ubbf8\ub178\uc0b0, \uc720\uc804\uc790\uac00 \uc801\uac8c \ubd84\uc0b0\ub418\ub294 \uc11c\ube0c\uc2a4\ud2b8\ub808\uc778 \ub610\ub294 \uacb0\ud569\uc744 \uc720\ubc1c\ud558\uae30 \uc26c\uc6b4 \ud3a9\ud2f0\ub4dc \uc1c4\uc5ec\uc5d0 \ub300\ud574\uc11c\ub294 \ub2e4\ub978 \ubc29\uc2dd\uc73c\ub85c \ubc18\uc751\ud560 \uc218 \uc788\ub2e4.<\/p>\n

\uc5ec\ub7ec \ubaa8\ub378 \ud654\ud569\ubb3c\uc5d0\uc11c Oxyma-B\ub97c \ube44\uad50\ud55c \uc5f0\uad6c\ub294 \uc5ec\ub7ec \uc11c\ube0c\uc2a4\ud2b8\ub808\uc778\uc5d0\uc11c \uacb0\ud569 \ud654\ud559\uc801 \ud2b9\uc131\uc744 \ud3c9\uac00\ud558\ub294 \uac83\uc774 \uc65c \uc720\uc6a9\ud560 \uc218 \uc788\ub294\uc9c0 \ubcf4\uc5ec\uc900\ub2e4.<\/p>\n

\uacb0\uad6d, \uc720\uc6a9\ud55c \uacb0\ud569 \ubc29\ubc95\uc740 \ud5c8\uc6a9 \uac00\ub2a5\ud55c \uc624\uc5fc\ubb3c\uc9c8 \ud504\ub85c\ud30c\uc77c\uacfc \ud568\uaed8 \ubaa9\uc801\uc758 \uad6c\uc870\ub97c \ub2ec\uc131\ud558\uace0 \ubaa9\ud45c \ud569\uc131 \uacb0\uacfc\uac00 \ubc18\ubcf5\ub418\ub3c4\ub85d \ud574\uc57c \ud55c\ub2e4.<\/p>\n

\ub530\ub77c\uc11c \uacb0\ud569 \ud6a8\uc728\uc131\uc744 \ub2e8\uc77c \uc791\uc6a9\uc81c \uc774\ub984\uc5d0 \uae30\uc778\ud558\ub294 \ud2b9\uc131\uc774\ub098 \ub2e8\uc77c \uc2dc\ud5d8\uc5d0\uc11c \ud655\uc778\ub41c \uc11c\ube0c\uc2a4\ud2b8\ub808\uc778 \uac10\uc18c \uacb0\uacfc\ub85c \uc124\uba85\ud558\ub294 \uac83\ubcf4\ub2e4 \ub354 \uc798 \uc774\ud574\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc790\uc8fc \ubb3b\ub294 \uc9c8\ubb38<\/h2>\n

1. \uc65c \ud3a9\ud0c0\uc774\ub4dc \ud569\uc131 \uc2dc \ubcf4\ud638\uae30 \uadf8\ub8f9\uc774 \ud544\uc694\ud569\ub2c8\uae4c?<\/h3>\n

\ubcf4\ud638 \uadf8\ub8f9\uc740 \ubd80\uc801\uc808\ud55c \ubc18\uc751\uc744 \uc77c\uc2dc\uc801\uc73c\ub85c \uc81c\ud55c\ud558\uc5ec, \uc801\uc808\ud55c \uae30\ub2a5 \uadf8\ub8f9\uc774 \uc758\ub3c4\ub41c \ud3a9\ud2f0\ub4dc \uacb0\ud569\uc744 \uc0dd\uc131\ud560 \uc218 \uc788\ub3c4\ub85d \ud569\ub2c8\ub2e4. \uc544\ubbf8\ub178\uc0b0\uc740 \uc5ec\ub7ec \uac1c\uc758 \ubc18\uc751 \uc9c0\uc810\uc774 \uc788\uc744 \uc218 \uc788\uc73c\uba70, \ubaa8\ub450\ub97c \ub3d9\uc2dc\uc5d0 \uc0ac\uc6a9\ud560 \uc218 \uc788\ub3c4\ub85d \ud558\ub294 \uac83\uc740 \uacbd\uc7c1\uc801\uc778 \ubc18\uc751\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud6a8\uacfc\uc801\uc778 \ubcf4\ud638 \uc804\ub7b5\uc740 \ub610\ud55c \ubcf4\ud638 \uadf8\ub8f9\uc758 \uc81c\uac70 \uac00\ub2a5\uc131\uc744 \uace0\ub824\ud574\uc57c \ud558\uba70, \ub610\ud55c \ubd84\uc790\uc758 \ub098\uba38\uc9c0 \ubd80\ubd84\uacfc \uc77c\uce58\ud574\uc57c \ud569\ub2c8\ub2e4. \ubaa8\ud615 \uc5f0\uad6c\ub294 \ubcf4\ud638 \uadf8\ub8f9 \uc120\ud0dd\uc774 \ubc18\uc751\uc758 \uae30\ubcf8 \uc120\ud0dd\uc131\uc5d0\ub9cc \uc601\ud5a5\uc744 \ubbf8\uce58\ub294 \uac83\uc774 \uc544\ub2c8\ub77c, \ubd80\uc791\uc6a9\uc758 \ubc1c\uc0dd\uc5d0\ub3c4 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc74c\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4. \ub530\ub77c\uc11c \ubcf4\ud638 \uadf8\ub8f9\uc740 \ud569\uc131 \uc804\ub7b5 \uc804\uccb4\uc758 \uad6c\uc131 \uc694\uc18c \uc911 \ud558\ub098\uc77c \ubfd0\uc774\uba70, \ubaa8\ub4e0 \ud654\ud559\uc801 \ubb38\uc81c\ub97c \ud574\uacb0\ud560 \uc218 \uc788\ub294 \uc77c\uad04\uc801\uc778 \ud574\uacb0\ucc45\uc740 \uc544\ub2d9\ub2c8\ub2e4.<\/p>\n

2. \uc62c\ubc14\ub978 \uacb0\ud569\uc774 \uacc4\uc18d\ud574\uc11c \uc624\uc5fc\ubb3c\uc9c8\uc758 \ubc1c\uc0dd\uc744 \uc720\ub3c4\ud560 \uc218 \uc788\ub294\uac00?<\/h3>\n

\uc608. \uc758\ub3c4\ub41c \ud3a9\ud2f0\ub4dc \uacb0\ud569\uc740 \ub3d9\uc77c\ud55c \ud63c\ud569\ubb3c \ub0b4\uc758 \ub2e4\ub978 \ubd84\uc790\ub4e4\uc774 \ubd80\ubd84\uc801\uc73c\ub85c \ubcc0\ud658\ub418\uac70\ub098 \ubc14\ub78c\uc9c1\ud558\uc9c0 \uc54a\uc740 \ubd80\uc791\uc6a9 \ubc18\uc751\uc744 \uc77c\uc73c\ud0a4\ub294 \ub3d9\uc548 \ubc1c\uc0dd\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud2b9\ud788 epimeric \uc81c\ud488\uc5d0 \ub300\ud55c \uc5f0\uad6c\ub294 \uc774\ub97c \uc798 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4. \uc801\uc808\ud55c \uacb0\ud569\uc744 \ud615\uc131\ud558\uace0 \uc801\uc808\ud55c stereochemistry\ub97c \uc720\uc9c0\ud558\ub294 \uac83\uc740 \uc11c\ub85c \ub2e4\ub978 \uac1c\ub150\uc774\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4. \ub530\ub77c\uc11c \ud45c\uc801 \ub2e8\ubc31\uc9c8\uc758 \ubc1c\uacac\uc740 \uadf8 \ub2e8\ubc31\uc9c8\uc774 \uc720\uc77c\ud55c \ud604\uc7ac \uc874\uc7ac\ud558\ub294 \uc81c\ud488\uc774\ub77c\ub294 \uac83\uc744 \uc758\ubbf8\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc131\uacf5\uc801\uc778 \uacb0\ud569\uc758 \uacfc\ud559\uc801 \uadfc\uac70\ub97c \uac16\ucd98 \ud3c9\uac00\uc5d0\ub294 \ubd84\uc11d\uc758 \ucd5c\uc885 \uc9c0\uc810\uc744 \uc815\uc758\ud558\uace0 \uc911\uc694\ud55c \uc624\uc5fc\ubb3c\uc9c8\uc5d0 \ub300\ud55c \uc815\ubcf4\ub97c \uc81c\uacf5\ud574\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

3. \ud398\ub9bd\ud2f0\ub4dc \uacb0\ud569\uc774 \uc804\uccb4 \ud398\ub9bd\ud2f0\ub4dc \ud569\uc131\uc5d0 \ud574\ub2f9\ub418\ub294\uac00?<\/h3>\n

\uc544\ub2c8\uc694. \uacb0\ud569\uc740 \ud6e8\uc52c \ub354 \uad11\ubc94\uc704\ud55c \ud569\uc131 \uacfc\uc815\uc758 \uc77c\ud658\uc73c\ub85c \uacb0\ud569\uc744 \uc0dd\uc131\ud558\ub294 \ub2e8\uc77c \ud504\ub85c\uc138\uc2a4\uc785\ub2c8\ub2e4. \uc0c1\uc218 \ub2e8\uacc4\uc5d0\uc11c\uc758 \ud569\uc131\uc5d0\ub294 \ub610\ud55c \ub9e4\uccb4\uc5d0 \uacb0\ud569, \ubcf4\ud638 \uadf8\ub8f9\uc758 \uc548\uc815\ud654, \uc81c\uac70, \ubc18\ubcf5\uc801\uc778 \ud0c8\ucc29, \ubd84\ub9ac, \uac00\uacf5, \uc815\uc81c \ubc0f \ucd5c\uc885 \ud2b9\uc131\uae4c\uc9c0 \ud3ec\ud568\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uacb0\ud569 \uc678\uc5d0\ub3c4 \ubd88\ud544\uc694\ud55c \ubd80\uc0b0\ubb3c\ub4e4\uc774 \uc0dd\uc131\ub420 \uc218 \uc788\uc73c\ubbc0\ub85c, \ucd5c\uc885 \uc624\uc5fc\uc740 \uacb0\ud569 \ub2e8\uacc4 \uc774\uc678\uc5d0\uc11c \ubc1c\uc0dd\ud55c \uac83\uc774\ub77c\uace0 \uc790\ub3d9\uc801\uc73c\ub85c \ud310\ub2e8\ud574\uc11c\ub294 \uc548 \ub429\ub2c8\ub2e4. \uc774\ub294 \ub370\uc774\ud130\uac00 \uadf8 \uc6d0\uc778\uc774 \uc2e4\uc81c\ub85c \ubb34\uc5c7\uc778\uc9c0 \uba85\ud655\ud788 \ubc1d\ud600\uc9c0\uae30 \uc804\uae4c\uc9c0\ub294 \uacb0\ud569\uc774 \uc798\ubabb\ub41c \uac83\uc774\ub77c\uace0 \ub2e8\uc815\ud574\uc11c\ub294 \uc548 \ub418\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4.<\/p>\n

4. \uc65c \ubcf4\ub974\ub3c4 \uadf8\ub8f9\uc774 \ud65c\uc131\ud654\ub429\ub2c8\uae4c?<\/h3>\n

\ubd80\uc2e4\ud654 \uadf8\ub8f9\uc758 \ud65c\uc131\ud654\ub294 \uadf8 \ubc18\uc751\uc744 \uc801\uc808\ud55c \uc544\ubbf8\ub178 \uadf8\ub8f9\uacfc \ub354 \uc720\ub9ac\ud558\uac8c \uc5f0\uacb0\uc2dc\ucf1c \uc544\ubbf8\ub4dc \uacb0\ud569\uc758 \uc0dd\uc131\uc5d0 \ub3c4\uc6c0\uc744 \uc90d\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc99d\uac00\ub41c \ubc18\uc751\uc131\uc740 \uacbd\uc7c1\uc801\uc778 \ubc18\uc751\ub3c4 \uac00\ub2a5\ud558\uac8c \ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \uacb0\ud569 \uc0dd\uc131 \ud6a8\uc728\uc131\ubfd0\ub9cc \uc544\ub2c8\ub77c, \ub3d9\uc801 \uc2a4\ud2f0\uc5b4\ub9c1 \ud6a8\uacfc\uc640 \ubd80\uc791\uc6a9 \uc0dd\uc131\uc5d0 \ub300\ud55c \ubd84\uc11d\uc744 \uc2dc\uc2a4\ud15c \uacb0\ud569 \ud3c9\uac00 \uc2dc \uace0\ub824\ud569\ub2c8\ub2e4. \ud65c\uc131\ud654\uc758 \ubaa9\uc801\uc740 \ubd84\uc790\uc758 \ubc18\uc751\uc131\uc744 \ucd5c\ub300\ud654\ud558\ub294 \uac83\uc774 \uc544\ub2c8\ub77c \ubc18\uc751\uc758 \uc801\uc808\ud55c \uc120\ud0dd\uc131\uc744 \ub2ec\uc131\ud558\ub294 \uac83\uc785\ub2c8\ub2e4.<\/p>\n

5. HATU\ub294 \ubb34\uc5c7\uc744 \uc704\ud574 \uc0ac\uc6a9\ub429\ub2c8\uae4c?<\/h3>\n

HATU\ub294 \uc544\ubbfc \uacb0\ud569 \uc0dd\uc131\uc758 \uc6a9\uc774\ud654\ub97c \uc704\ud574 \uc0ac\uc6a9\ub418\ub294 \uacb0\ud569 \ucd09\uc9c4\uc81c\uc785\ub2c8\ub2e4. \uc774\ub294 \ud3a9\ud2f0\ub4dc \uacb0\ud569 \uc2dc\uc5d0\ub3c4 \ub9c8\ucc2c\uac00\uc9c0\uc785\ub2c8\ub2e4. \uc774\ub294 \ud3a9\ud2f0\ub4dc \ub610\ub294 \ubcf4\ud638 \uadf8\ub8f9\uc774 \uc544\ub2d9\ub2c8\ub2e4. \ub2e8\ubc31\uc9c8 \uc11c\uc5f4\uc774 \ubcf5\uc7a1\ud55c \uacbd\uc6b0\uc758 \ube44\uad50 \uc5f0\uad6c\ub294 HATU\ub97c \uc774\uc6a9\ud55c \ubc29\ubc95\uc744 \ubc18\uc751 \uc870\uac74\uc758 \uc804\uccb4 \ub9e5\ub77d\uc5d0\uc11c \ud3c9\uac00\ud574\uc57c \ud568\uc744 \ubcf4\uc5ec\uc900\ub2e4. HATU\uac00 \uc0ac\uc6a9\ub418\uc5c8\ub2e4\ub294 \uc815\ubcf4 \uc790\uccb4\ub85c\ub294 \uc644\uc804\ud55c \ubcc0\ud658, \uc2a4\ud14c\ub808\uc624\ubbf8\ub514\uc5b4\uc758 \uc720\uc9c0, \ub610\ub294 \ub354 \ub098\uc740 \uc624\uc5fc\ubb3c\uc9c8 \ud504\ub85c\ud30c\uc77c\uc744 \ubcf4\uc7a5\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n

6. \ud398\ub2c8\ud2b8\uc758 \uacb0\ud569\uc5d0 \uac00\uc7a5 \uc801\ud569\ud55c \uc131\ubd84\uc740 \ud558\ub098\ub77c\ub3c4 \uc788\ub294\uac00?<\/h3>\n

\uc544\ub2d9\ub2c8\ub2e4. \ubaa8\ub4e0 \ud3a9\ud2f0\ub4dc\uc640 \ubc18\uc751\uc5d0 \uc801\ud569\ud55c \uc644\ubcbd\ud55c \ubc18\uc751\uae30 \ubaa9\ub85d\uc740 \uc5c6\uc2b5\ub2c8\ub2e4. \uacbd\ud654\ub3c4, \uc11c\ube0c\uc2a4\ud2b8\ub77c\ud2b8 \uc6a9\ud574\ub3c4, \uacb0\ud569\ub3c4, \ud3b8\ud5a5\uc131, \uc2a4\ud14c\ub808\uc624\uc2dc\uba58\ud2f1\uc131 \ubc0f \uc11c\uc5f4 \ucee8\ud14d\uc2a4\ud2b8\ub294 \uacb0\uacfc\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \ubc18\uc751\uae30 \uc120\ud0dd\uc740 \ud2b9\uc815 \ubc18\uc751\uc5d0 \ub300\ud55c \uce21\uc815\ub41c \uacb0\uacfc\uc5d0 \uae30\ubc18\ud574\uc57c \ud558\uba70, \uadf8\uc800 \uadf8 \ubc18\uc751\uc758 \ud3c9\ud310\uc774\ub098 \uc778\uae30\uc5d0\ub9cc \uc758\uc874\ud574\uc11c\ub294 \uc548 \ub429\ub2c8\ub2e4.<\/p>\n

7. \u201e\uc5f0\uacb0\uc81c\u201d\uc640 \u201e\ucca8\uac00\uc81c\u201d\ub294 \uac19\uc740 \uc758\ubbf8\uc778\uac00\uc694?<\/h3>\n

\uc544\ub2c8\uc694. \uc774\ub7ec\ud55c \uc6a9\uc5b4\ub4e4\uc740 \uacb0\ud569 \uc2dc\uc2a4\ud15c \ub0b4\uc758 \ub2e4\uc591\ud55c \uae30\ub2a5\uc744 \uc124\uba85\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uacb0\ud569 \ucd09\ub9e4\ub294 \uc9c1\uc811 \ud65c\uc131\ud654\uc5d0 \uad00\uc5ec\ud560 \uc218 \uc788\uc9c0\ub9cc, \ucca8\uac00\ubb3c\uc740 \uc911\uac04 \uc81c\ud488 \uc0dd\uc131, \ubc18\uc751 \ud6a8\uc728\uc131, \uc0bc\uc704\uc131 \uc644\uc804\uc131 \ub610\ub294 \uacbd\uc7c1\uc801\uc778 \ud654\ud559 \uacbd\ub85c\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc804\uccb4 \ubc18\uc751 \uc2dc\uc2a4\ud15c\uc744 \ubd84\uc11d\ud574\uc57c \ud558\uba70, \ubaa8\ub4e0 \uad6c\uc131 \uc694\uc18c\ub4e4\uc744 \uc11c\ub85c \ub300\uccb4\ud560 \uc218 \uc788\ub294 \ub300\uc548\uc73c\ub85c \uac04\uc8fc\ud574\uc11c\ub294 \uc548 \ub429\ub2c8\ub2e4.<\/p>\n

8. \ub2e8\uc77c \uc544\ubbf8\ub178\uc0b0 \ub300\uc2e0 \uc804\uccb4 \ub2e8\ubc31\uc9c8 \uc870\uac01\ub4e4\uc744 \uacb0\ud569\ud560 \uc218 \uc788\ub098\uc694?<\/h3>\n

\ub124. \uacb0\ud569 \ubc18\uc751\uc740 \ub2e8\uc77c \uc544\ubbf8\ub178\uc0b0\ubfd0\ub9cc \uc544\ub2c8\ub77c \ub354 \ud070 \ubcf4\ud638\ub41c \ud53c\uc5d0\ub2e4\ud3a9\ud2f0\ub4dc \uc870\uac01\ub4e4\uc744 \uacb0\ud569\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ubc18\uc751 \uc131\ubd84\ub4e4\uc758 \ud06c\uae30\ub97c \uc99d\uac00\uc2dc\ud0a4\ub294 \uac83\uc740 \ubc18\uc751 \uc704\uce58\uc758 \uc120\ud0dd\uc131, \uc785\uccb4\uc131 \ubc0f \ucd5c\uc885 \uc81c\ud488 \ud2b9\uc131\uc744 \uc81c\uc5b4\ud560 \ud544\uc694\uc131\uc744 \uc81c\uac70\ud558\uc9c0\ub294 \uc54a\uc2b5\ub2c8\ub2e4. \ubd80\ubd84\ub4e4\uc744 \uacb0\ud569\ud558\ub294 \uacbd\uc6b0\uc5d0\ub3c4, \uc62c\ubc14\ub978 \uc5f0\uacb0\uc774 \uc2e4\uc81c\ub85c \uc81c\ub300\ub85c \uc774\ub8e8\uc5b4\uc84c\ub294\uc9c0 \ud655\uc778\ud558\ub294 \ub370\uc774\ud130\uac00 \uc5ec\uc804\ud788 \ud544\uc694\ud569\ub2c8\ub2e4.<\/p>\n

9. \ub77c\uc2dc\uba54\uc774\uc158\uacfc \uc5d0\ud53c\uba54\ub9ac\uc790\uc774\uc158\uc758 \ucc28\uc774\uc810\uc740 \ubb34\uc5c7\uc778\uac00\uc694?<\/h3>\n

\uc2e4\uc9c8\uc801\uc778 \uc758\ubbf8\uc5d0\uc11c\uc758 \ub77c\uc138\ubbf8\ud654\ub294 \uc5d0\ub09c\uc2dc\ubaa8\uba54\ub9ac\uc998\uc758 \ud48d\ubd80\ud568\uc744 \ud5a5\ud55c \ubc29\ud5a5\uc73c\ub85c\uc758 \ubcc0\ud654\ub97c \uc758\ubbf8\ud558\uba70, \ubc18\uba74 \uc5d0\ud53c\uba54\ub9ac\ud654\ub294 \uc5ec\ub7ec \uac1c\uc758 \uac19\uc740 \uc5d0\ub09c\uc2dc\ubaa8\uba54\ub9ac\uc998 \uc911\uc2ec\uc744 \ud3ec\ud568\ud558\ub294 \ubd84\uc790 \ub0b4\uc758 \ud558\ub098\uc758 \uc911\uc2ec\uc758 \uad6c\uc870 \ubcc0\ud654\ub97c \uc758\ubbf8\ud55c\ub2e4. \uc13c\ud130\ub4e4. \ud3a9\ud0c0\uc774\ub4dc \ud569\uc131 \uad00\ub828 \ubb38\ud5cc\uc5d0\uc11c '\ub77c\uc138\ub9c8\ub974\uae30\uc2a4(racemization)'\ub77c\ub294 \uc6a9\uc5b4\ub294 \uc544\ubbf8\ub178\uc0b0 \uc794\uae30\uc758 \uad6c\uc870\uc801 \ubc30\uc5f4\uc774 \ubcc0\ud654\ud558\ub294 \uac83\uc744 \uc124\uba85\ud558\uae30 \uc704\ud574 \ub354 \uad11\ubc94\uc704\ud558\uac8c \uc0ac\uc6a9\ub429\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc815\ud655\ud55c \uc6a9\uc5b4\ub294 \uc2e4\uc81c \uad6c\uc870\uc801 \ubcc0\ud654\ub97c \ub098\ud0c0\ub0b4\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

10. \ub300\ub7c9 \ubd84\uc11d\ubc95\uc740 \ubaa8\ub4e0 stereochemical \uc624\ub958\ub97c \uac10\uc9c0\ud560 \uc218 \uc788\uc2b5\ub2c8\uae4c?<\/h3>\n

\uc544\ub2c8\uc694. \uc2a4\ud14c\ub85c\uc774\uc18c\uba54\uc5b4\ub4e4\uc740 \uc815\ud655\ud788 \uac19\uc740 \ubd84\uc790\ub7c9\uc744 \uac00\uc9c8 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ubbc0\ub85c \uae30\ub300\ub41c \uc9c8\ub7c9\uc744 \uc5bb\ub294 \uac83\uc740 \uac01 \uc2a4\ud14c\ub85c\uc774\uc18c\uba54\uc5b4\uc758 \uc815\ud655\ud55c \uad6c\uc131\uc744 \ubcf4\uc7a5\ud558\uc9c0\ub294 \uc54a\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ucc28\uc774\uc810\uc744 \ud3c9\uac00\ud558\uae30 \uc704\ud574 \ucd94\uac00\uc801\uc778 \ubc29\ubc95\uc774 \ud544\uc694\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4 \uc801\uc808\ud55c \ud06c\ub85c\ub9c8\ud1a0\uadf8\ub798\ud53c \uae30\uc220 \ub610\ub294 \ub514\uc5b4\ubc14\ud2f0\uc9c0 \uc804\ub7b5\uc774 \ud544\uc694\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc9c8\ub7c9 \ubd84\uad11\ubc95\uc740 \ubd84\uc790 \ud2b9\uc131 \ubd84\uc11d\uc5d0 \ub9e4\uc6b0 \uc720\uc6a9\ud55c \ub3c4\uad6c\uc774\uc9c0\ub9cc, \uadf8 \uacb0\uacfc\ub294 \ud2b9\uc815 \uad6c\uc870\uc801 \uc9c8\ubb38\uc758 \ud55c\uacc4\uc5d0 \ub530\ub77c \ud574\uc11d\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

11. \uc544\uc2a4\ud30c\ub974\ud2f0\ubbf8\ub4dc \uc0dd\uc131\uc740 \ub2e8\uc21c\ud788 \uacb0\ud569\uc774 \uc2e4\ud328\ud588\uc74c\uc744 \uc758\ubbf8\ud558\ub294\uac00?<\/h3>\n

\uc544\ub2c8\uc694. \uc544\uc2a4\ud30c\ub974\ud2f0\ubbf8\ub4dc\uc758 \uc0dd\uc131\uc740 \uc544\uc2a4\ud30c\ub77c\uae34\uc0b0\uc744 \ud568\uc720\ud558\ub294 \ubbfc\uac10\ud55c \uc11c\uc5f4\uacfc \uad00\ub828\ub41c \ubcc4\uac1c\uc758 \ubd80\uc791\uc6a9 \ubc18\uc751 \uacbd\ub85c\uc785\ub2c8\ub2e4. \uc774 \ud604\uc0c1\uc740 \uc778\uc811\ud55c \uc794\uae30\ub4e4\uacfc \ubcf4\ud638\uae30 \uc81c\uac70 \uc870\uac74\uc5d0 \uc758\ud574 \uc601\ud5a5\uc744 \ubc1b\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc801\uc808\ud55c \uc544\ubbf8\ub178\uc0b0\uc744 \uc774\uc804\ubcf4\ub2e4 \uc62c\ubc14\ub974\uac8c \uacb0\ud569\ud55c \uacbd\uc6b0\uc5d0\ub3c4 \ubc14\ub78c\uc9c1\ud558\uc9c0 \uc54a\uc740 \uad6c\uc870\uc801 \ubcc0\ud654\uac00 \ubc1c\uc0dd\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc624\uc5fc\ubb3c\uc758 \uae30\uc6d0\uc744 \uaddc\uba85\ud558\ub294 \uac83\uc740 \uc911\uc694\ud569\ub2c8\ub2e4. \uc65c\ub0d0\ud558\uba74 \ubc18\uc751 \uacbd\ub85c\uac00 \uc644\uc804\ud788 \ub2e4\ub978 \uacbd\uc6b0\uc5d0\ub3c4 \uacb0\ud569\uc774 \ubc18\ubcf5\ub420 \uc218 \uc788\uae30 \ub54c\ubb38\uc5d0 \ubb38\uc81c\uac00 \ud574\uacb0\ub418\uc9c0 \uc54a\uc744 \uc218 \uc788\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4.<\/p>\n

12. \uacb0\ud569 \uc7ac\ud604\uc774 \ubc18\uc751\uc758 \uc131\uacf5\uc744 \ubcf4\uc7a5\ud558\ub294\uac00?<\/h3>\n

\uc544\ub2c8\uc694. \uc77c\ubd80 \uacbd\uc6b0\uc5d0 \uc7ac\uacb0\ud569\uc744 \ubc18\ubcf5\ud558\uba74 \uc804\ud658\uc728\uc744 \uac1c\uc120\ud560 \uc218 \uc788\uc9c0\ub9cc, \ubaa8\ub4e0 \ubc18\uc751 \uc9c0\uc810\uc774 \uc774\uc6a9 \uac00\ub2a5\ud574\uc9c0\ub294 \uac83\uc740 \ubb3c\ub860\uc774\uace0 \ub2e4\ub978 \ubd80\uc791\uc6a9\ub3c4 \ubcf4\uc7a5\ud558\uc9c0\ub294 \uc54a\uc2b5\ub2c8\ub2e4. \uadf8\ub4e4\uc740 \uc81c\uac70\ub420 \uac83\uc774\ub2e4. \uacb0\uacfc\ub294 \uc5ec\uc804\ud788 \uc7ac\ub8cc\uc640 \uc0ac\uc6a9\ub41c \ubc29\ubc95\uc5d0 \ub530\ub77c \ub2ec\ub77c\uc9d1\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc2e4\uc81c\ub85c \ucd94\uac00 \uacb0\ud569\uc744 \uc720\ub3c4\ud55c \uc694\uc18c\ub97c \ud30c\uc545\ud558\uae30 \uc704\ud574 \uc81c\ud488 \ubd84\uc11d\uc774 \ud544\uc694\ud569\ub2c8\ub2e4.<\/p>\n

13. \ub354 \ub192\uc740 \uc628\ub3c4\uac00 \ud56d\uc0c1 \uc811\ud569 \ud488\uc9c8\uc744 \ud5a5\uc0c1\uc2dc\ud0ac\uae4c\uc694?<\/h3>\n

\uc544\ub2c8\uc694. \uc628\ub3c4 \uc0c1\uc2b9\uc740 \uc6d0\ud558\ub294 \ubc18\uc751\uc744 \uac00\uc18d\ud654\ud560 \uc218 \uc788\uc9c0\ub9cc, \uc6d0\uce58 \uc54a\ub294 \ud654\ud559 \ubc18\uc751\ub3c4 \ucd09\uc9c4\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ubbc0\ub85c \ub354 \ube60\ub978 \ubcc0\ud658\uc744 \uc790\ub3d9\uc73c\ub85c \ud654\ud559\uc801 \ud488\uc9c8 \uac1c\uc120\uc73c\ub85c \ud574\uc11d\ud574\uc11c\ub294 \uc548 \ub429\ub2c8\ub2e4. \uc628\ub3c4 \uc870\uc808\uc740 \ucd5c\uc885 \uc81c\ud488 \uc0dd\uc131 \uce21\uba74\uacfc \uc0dd\uc131\ub41c \uc624\uc5fc\ubb3c\uc9c8\uc758 \ud2b9\uc131\uc5d0 \ub530\ub77c \ud3c9\uac00\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

14. \uc790\uc720 \uc544\ubbfc \uadf8\ub8f9\uc758 \uc18c\uc2e4\uc774 \uc62c\ubc14\ub978 \ub2e8\ubc31\uc9c8\uc758 \uc0dd\uc131\uc744 \uc758\ubbf8\ud569\ub2c8\uae4c?<\/h3>\n

\uc544\ub2c8\uc694. \uac80\ucd9c \uac00\ub2a5\ud55c \uc790\uc720 \uc544\ubbf8\ub178 \uadf8\ub8f9\uc774 \uc5c6\ub2e4\ub294 \uac83\uc740 \uc0ac\uc6a9\ub41c \uac80\uc0ac\uc758 \uc870\uac74\uc5d0\uc11c \ud2b9\uc815 \uae30\ub2a5 \uadf8\ub8f9\uc5d0 \ub300\ud55c \ud6e8\uc52c \ub354 \uc81c\ud55c\ub41c \uc9c8\ubb38\uc5d0 \ub2f5\ud558\ub294 \uac83\uc785\ub2c8\ub2e4. \uadf8\uac83\uc740 \ub2e8\ubc31\uc9c8\uc758 \uc644\uc804\ud55c \uc11c\uc5f4, \uc2a4\ud14c\ub808\uc624\ubbf8\ud130 \ubc0f \uc21c\ub3c4\ub97c \uc9c1\uc811\uc801\uc73c\ub85c \ud655\uc778\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \ubb34\uae30\uc0b0 \uc790\uc720 \uadf8\ub8f9\uc758 \ubaa8\ub2c8\ud130\ub9c1\uc740 \uacf5\uc815 \uad00\ub9ac\uc5d0 \uc720\uc6a9\ud55c \uc694\uc18c\uac00 \ub420 \uc218 \uc788\uc9c0\ub9cc, \ucd5c\uc885 \uc81c\ud488 \ud2b9\uc131\uc744 \ub300\uccb4\ud558\uc9c0\ub294 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n

15. HPLC\uc758 \uc21c\ub3c4\ub294 \uacb0\ud569 \ud6a8\uc728\uc131\uacfc \ub3d9\uc77c\ud55c\uac00\uc694?<\/h3>\n

\uc544\ub2c8\uc694. HPLC\uc758 \uc21c\ub3c4\uc640 \uc131\ub2a5\uc740 \uc11c\ub85c \ub2e4\ub978 \ud2b9\uc131\uc744 \uc124\uba85\ud569\ub2c8\ub2e4. HPLC\uc758 \uc21c\ub3c4\ub294 \uac80\ucd9c\ub41c \uc2dc\ub8cc \uc131\ubd84\uc758 \ud568\ub7c9\uc5d0 \ub530\ub77c \uacb0\uc815\ub418\uc9c0\ub9cc, \uc0dd\uc0b0\uc131\uc740 \uc815\uc758\ub41c \uc6d0\ub8cc \uc591\uc5d0 \ube44\ub840\ud558\uc5ec \ud2b9\uc815 \uc81c\ud488\uc758 \uc591\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4. \uc138\uc815\uc740 \ud06c\ub85c\ub9c8\ud1a0\uadf8\ub798\ud53c\uc758 \uc21c\ub3c4\ub97c \ub192\uc774\uba74\uc11c \ub3d9\uc2dc\uc5d0 \uc7ac\uc21c\ud658\ub41c \ucd5c\uc885 \uc81c\ud488\uc758 \uc591\uc744 \uc904\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \ud574\ub2f9 \uac12\uc774 \uc815\ud655\ud788 \ubb34\uc5c7\uc744 \ub098\ud0c0\ub0b4\ub294\uc9c0\ub97c \uba85\ud655\ud788 \ubc1d\ud788\uc9c0 \uc54a\ub294\ub2e4\uba74, \uadf8 \uac12\uc758 \ubc31\ubd84\uc728\uc740 \uc911\uc694\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n

16. \uacb0\ud569\uc774 \ub05d\ub09c \ud6c4\uc5d0\ub3c4 \uc624\uc5fc\uc774 \ubc1c\uc0dd\ud560 \uc218 \uc788\ub098\uc694?<\/h3>\n

\ub124. \ubc18\uc751\uc774 \ub05d\ub09c \ud6c4, \ub2e8\ubc31\uc9c8 \ud569\uc131\uc740 \ucd94\uac00 \ud654\ud559 \ub2e8\uacc4\ub4e4\uc744 \ud3ec\ud568\ud569\ub2c8\ub2e4. \ubcf4\ud638 \uadf8\ub8f9\uc758 \uc81c\uac70, \ubd84\ub9ac \ubc0f \uadf8 \ud6c4\uc758 \uac00\uacf5\uc740 \ubd84\uc790\ub97c \ubcc0\ud615\uc2dc\ud0a4\uac70\ub098 \ucd94\uac00 \uc624\uc5fc\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub294 \ubaa8\ub4e0 \ucd5c\uc885 \uc624\uc5fc\uc774 \ud6c4\uae30 \ub2e8\uacc4\uc5d0\uc11c \ubc1c\uc0dd\ud55c\ub2e4\ub294 \uac83\uc744 \uc758\ubbf8\ud558\ub294 \uac83\uc740 \uc544\ub2c8\uc9c0\ub9cc, \uc62c\ubc14\ub978 \uacb0\ud569\uc774 \ucd5c\uc885 \uc81c\ud488\uc758 \ud488\uc9c8 \ubcf4\uc99d\uc774 \ub420 \uc218 \uc5c6\ub294 \uc774\uc720\ub97c \ubcf4\uc5ec\uc90d\ub2c8\ub2e4.<\/p>\n

17. \ubb34\uc5c7\uc774 \uacb0\ud569 \ubc29\ubc95\uc758 \ube44\uad50\uac00 \uc2e0\ube59\uc131\uc744 \uac16\uac8c \ud558\ub294\uac00?<\/h3>\n

\uc2e0\ube59\uc131 \uc788\ub294 \ube44\uad50\ub294 \ub3d9\uc77c\ud55c \uba85\ud655\ud558\uac8c \uc815\uc758\ub41c \ubaa9\ud45c\ub97c \ub2ec\uc131\ud558\uae30 \uc704\ud55c \ub300\uc548\uc801\uc778 \ubc29\ubc95\uacfc \ucda9\ubd84\ud788 \ube44\uad50 \uac00\ub2a5\ud55c \uc870\uac74\uc5d0\uc11c \ud3c9\uac00\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4. \uc801\uc6a9\ub41c \uc11c\ube0c\uc2a4\ud2b8\ub808\uc778, \uc2dc\ub8cc \uc218\uc9d1 \ub2e8\uacc4, \ubd84\uc11d \ubc29\ubc95 \ubc0f \uac80\ud1a0\ub41c \uc624\uc5fc\ubb3c\uc9c8 \uc720\ud615\uc744 \uc81c\uc2dc\ud558\ub294 \uac83\uc774 \uc544\ub2c8\ub77c, \uba85\ud655\ud558\uac8c \ubc1d\ud600\uc9c0\uc9c0 \uc54a\uc740 \ubc31\ubd84\uc728 \uac12\uc744 \uc81c\uc2dc\ud558\uac70\ub098 \ucd09\ub9e4\uc758 \ud3c9\ud310\uc5d0 \uc758\uc874\ud558\ub294 \uac83\uc774 \ubc14\ub78c\uc9c1\ud569\ub2c8\ub2e4. \uc5ec\ub7ec \uac00\uc9c0 \ub2e4\uc591\ud55c \ubaa8\ub378 \ub2e8\ubc31\uc9c8\uc744 \ud3ec\ud568\ud558\ub294 \ube44\uad50\ub294 \uac04\ub2e8\ud55c \uc11c\ube0c\uc2a4\ud2b8\ub808\uc778\uc5d0 \ub300\ud574 \uc5bb\uc5b4\uc9c4 \ub192\uc740 \ud6a8\uc728\ubcf4\ub2e4 \ub354 \ub9ce\uc740 \uc815\ubcf4\ub97c \uc81c\uacf5\ud560 \uc218 \uc788\uc73c\uba70, \uc774\ub294 \ubd84\uc790\uc801 \ub9e5\ub77d\uc5d0 \ub530\ub77c \ud6a8\uc728\uc131\uc774 \uc5b4\ub5bb\uac8c \ubcc0\ud654\ud558\ub294\uc9c0\ub97c \ubcf4\uc5ec\uc90d\ub2c8\ub2e4. \ub610\ud55c \uadf8 \uacb0\ub860\uc740 \uc2e4\uc81c\ub85c \uac80\uc99d\ub41c \ud654\ud559 \uc2dc\uc2a4\ud15c\uc73c\ub85c \uc81c\ud55c\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\uc694\uc57d<\/h2>\n

\ud3a9\ud0c0\uc774\ub4dc \uacb0\ud569\uc740 \ud3a9\ud0c0\uc774\ub4dc \ud569\uc131\uc758 \uae30\ubcf8 \uc694\uc18c\uc785\ub2c8\ub2e4. \uc774\ub294 \ud3a9\ud0c0\uc774\ub4dc \uad6c\uc870 \ub0b4\uc758 \uc544\ubbf8\ub178\uc0b0 \uc794\uae30\ub97c \uc5f0\uacb0\ud558\ub294 \uc544\ubbf8\ub4dc \uacb0\ud569\uc744 \uc0dd\uc131\ud558\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ub2e8\uc9c0 \u201e\uc544\ubbf8\ub178\uc0b0 \ub450 \uac1c\uc758 \uacb0\ud569\u201d\uc73c\ub85c \ud3a9\ud0c0\uc774\ub4dc \uacb0\ud569\uc744 \uc124\uba85\ud558\ub294 \uac83\uc740, \ud574\ub2f9 \uc81c\ud488\uc774 \uc2e4\uc81c\ub85c \uc758\ub3c4\ub41c \ud3a9\ud0c0\uc774\ub4dc\uc778\uc9c0 \uc5ec\ubd80\uc5d0 \uacb0\uc815\uc801\uc778 \uc601\ud5a5\uc744 \ubbf8\uce58\ub294 \uc0c1\ub2f9\ud55c \ud654\ud559\uc801 \uba54\ucee4\ub2c8\uc998\uc744 \uac04\uacfc\ud558\ub294 \uac83\uc785\ub2c8\ub2e4.<\/p>\n

\ubcf4\ub974\ub3c4 \uadf8\ub8f9\uc744 \ud3ec\ud568\ud558\ub294 \uc131\ubd84\uc740 \uc77c\ubc18\uc801\uc73c\ub85c \ud65c\uc131\ud654\uac00 \ud544\uc694\ud558\uba70, \ud6a8\uacfc\uc801\uc778 \uc544\ubbf8\ub4dc \uacb0\ud569\uc744 \uc704\ud574\uc11c\ub294 \ud65c\uc131\ud654\uac00 \ud544\uc694\ud569\ub2c8\ub2e4. \uc811\ucc29\uc81c \ubc0f \ucca8\uac00\uc81c\ub294 \uc774 \uacfc\uc815\uc744 \ucd09\uc9c4\ud560 \uc218 \uc788\uc9c0\ub9cc, \uadf8\ub4e4\uc758 \ud6a8\uacfc\ub294 \uc18c\uc7ac, \ubc18\uc751 \ud658\uacbd \ubc0f \ubd84\uc11d \uacb0\uacfc\uc758 \ud574\uc11d \ubc29\uc2dd\uc5d0 \ub530\ub77c \ub2ec\ub77c\uc9d1\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc131\ubd84\uc744 \uc2e4\ud5d8\uc801 \uc804\uccb4 \ub9e5\ub77d\uc5d0\uc11c \ubd84\uc11d\ud574\uc57c \ud558\uba70, \ud569\uc131\ub41c \ud3a9\ud2f0\ub4dc\uc640 \ubb34\uad00\ud558\uac8c \ubd84\ub958\ud574\uc11c\ub294 \uc548 \ub429\ub2c8\ub2e4.<\/p>\n

\ubcf4\ud638 \uadf8\ub8f9\uc740 \ubd88\ud544\uc694\ud55c \uae30\ub2a5 \uadf8\ub8f9\uc774 \ubc18\uc751\uc5d0 \ucc38\uc5ec\ud558\ub294 \uac83\uc744 \uc77c\uc2dc\uc801\uc73c\ub85c \ub9c9\uc544\uc8fc\ub294 \ubc29\uc2dd\uc73c\ub85c \ub610 \ub2e4\ub978 \uc218\uc900\uc758 \uc81c\uc5b4\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. \uadf8\ub4e4\uc758 \uc720\uc6a9\uc131\uc740 \ud6a8\uacfc\uc801\uc778 \ubcf4\ud638\ubfd0\ub9cc \uc544\ub2c8\ub77c \uc120\ud0dd\uc801 \uc81c\uac70 \ub2a5\ub825\uacfc \uc5f0\uc18d \ud569\uc131 \ub2e8\uacc4\uc758 \uc77c\uce58 \uc5ec\ubd80\uc5d0 \ub2ec\ub824 \uc788\uc2b5\ub2c8\ub2e4. \ubcf4\ud638 \uc804\ub7b5\uacfc \uc778\uc811\ud55c \uc544\ubbf8\ub178\uc0b0 \uc794\uc7ac\ub4e4\uc740 \ub610\ud55c \ud2b9\uc815 \ubd80\uc791\uc6a9\uc758 \ubc1c\uc0dd\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc774\uc911\uc131 \uc644\uc804\uc131\uc740 \ub610 \ub2e4\ub978 \uc911\uc694\ud55c \uc694\uc18c\uc785\ub2c8\ub2e4. \uacb0\ud569 \ubc18\uc751\uc740 \uc544\ubbfc \uacb0\ud569\uc744 \uc0dd\uc131\ud560 \uc218 \uc788\uc73c\uba70 \ub3d9\uc2dc\uc5d0 \uc774\uc628\uc131 \ubb3c\uc9c8\uc744 \uc0dd\uc131\ud560 \uc218\ub3c4 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ud30c\uc774\uba38\ub294 \uc62c\ubc14\ub978 \ud3a9\ud2f0\ub4dc\uc640 \ub3d9\uc77c\ud55c \ubd84\uc790\ub7c9\uc744 \uac00\uc9c8 \uc218 \uc788\uae30 \ub54c\ubb38\uc5d0, \uc790\uccb4 \uc9c8\ub7c9 \uc77c\uce58\ub9cc\uc73c\ub85c \uad6c\uc870\uc801 \uc815\ud655\uc131\uc744 \uc644\uc804\ud788 \ubcf4\uc7a5\ud560 \uc218\ub294 \uc5c6\uc2b5\ub2c8\ub2e4. \uad6c\uc131\ubcc0\ud654\ub294 \ub610\ud55c \uc544\ubbf8\ub178\uc0b0\uc774 \uace0\uccb4 \ub2e8\uacc4\uc5d0 \uacb0\ud569\ub418\ub294 \ucd08\uae30 \ub2e8\uacc4\uc640 \uac19\uc740 \ub2e4\ub978 \ub2e8\uacc4\uc5d0\uc11c\ub3c4 \ubc1c\uc0dd\ud560 \uc218 \uc788\ub2e4.<\/p>\n

\ub2e4\ub978 \uc624\uc5fc\ubb3c\uc9c8\uc740 \ub2e4\ub978 \uba54\ucee4\ub2c8\uc998\uc744 \ud1b5\ud574 \uc0dd\uc131\ub429\ub2c8\ub2e4. \ubd88\uc644\uc804\ud55c \uacb0\ud569\uc740 \ub514\ub808\uc2dc\ubc8c \ub610\ub294 \uc2a4\ud06c\ub8e8\ud504\ub2dd \uc2dc\ud000\uc2a4\uc758 \ubc1c\uc0dd\uc744 \uc720\ub3c4\ud560 \uc218 \uc788\uc9c0\ub9cc, \uc544\uc2a4\ud30c\ud2f0\ubbf8\ub4dc \uad00\ub828 \ubc18\uc751\uc740 \uc774\ubbf8 \uc801\uc808\ud55c \uc544\ubbf8\ub178\uc0b0 \uc794\uc7ac\ub97c \ud3ec\ud568\ud558\ub294 \ub2e8\ubc31\uc9c8\uc744 \ubcc0\ud615\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud504\ub85c\uc138\uc2a4\uc758 \uac00\uc18d\ud654\ub294 \ubc14\ub78c\uc9c1\ud55c \ubc18\uc751\ubfd0\ub9cc \uc544\ub2c8\ub77c \ubcf4\uc870 \uacbd\ub85c\uc5d0\ub3c4 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc73c\uba70, \ucd94\uac00 \uc624\uc5fc\ubb3c\uc9c8\uc740 \ud0c8\ucc29\uacfc \uac19\uc740 \ud6c4\uc18d \ub2e8\uacc4\uc5d0\uc11c\ub3c4 \ubc1c\uc0dd\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc774\ub7ec\ud55c \uc774\uc720\ub85c \ub2e8\ubc31\uc9c8\uc758 \uacb0\ud569 \uc815\ub3c4\ub97c \ud3c9\uac00\ud558\uae30 \uc704\ud574\uc11c\ub294 \uc6d0\ub8cc \ubb3c\uc9c8\uc774 \uc0ac\ub77c\uc84c\ub294\uc9c0 \uc5ec\ubd80\ub97c \ud655\uc778\ud558\ub294 \uac83 \uc774\uc0c1\uc758 \uac83\uc774 \ud544\uc694\ud569\ub2c8\ub2e4.<\/p>\n

\ubcc0\ud658, \ucd5c\uc885 \uc81c\ud488\uc758 \uc0dd\uc131, \uace0\ub9bd\ub41c \ud6a8\uc728\uc131, \ud06c\ub85c\ub9c8\ud1a0\uadf8\ub798\ud53c\uc758 \uc21c\ub3c4 \ubc0f \uc5ed\uce21\uc131 \uc21c\ub3c4\ub294 \ub2e4\uc591\ud55c \uc9c8\ubb38\uc5d0 \ub2f5\ud569\ub2c8\ub2e4.<\/p>\n

\ud569\uc131 \uacfc\uc815\uc5d0\uc11c \uc218\ud589\ub418\ub294 \uac80\uc0ac\ub294 \ubd88\uc644\uc804\ud55c \ubc18\uc751\uc744 \ud0d0\uc9c0\ud558\ub294 \ub370 \ub3c4\uc6c0\uc744 \uc904 \uc218 \uc788\uc9c0\ub9cc, \ub2e8\ubc31\uc9c8\uc758 \uc644\uc804\ud55c \uad6c\uc870\ub97c \uc9c1\uc811\uc801\uc73c\ub85c \ud655\uc778\ud558\uc9c0\ub294 \ubabb\ud569\ub2c8\ub2e4. \ud06c\ub85c\ub9c8\ud1a0\uadf8\ub798\ud53c\uc640 \ubd84\uc790\ub7c9 \ubd84\uc11d\uc740 \uc11c\ub85c \ubcf4\uc644\uc801\uc778 \uc815\ubcf4\ub97c \uc81c\uacf5\ud558\uc9c0\ub9cc, \uc0bc\uc6d0\uc131 \ub610\ub294 \ub9e4\uc6b0 \uc720\uc0ac\ud55c \uad6c\uc870\uc5d0 \uad00\ud55c \uc9c8\ubb38\uc740 \ucd94\uac00\uc801\uc778 \ubd84\uc11d \ubc29\ubc95\uc744 \ud544\uc694\ub85c \ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub530\ub77c\uc11c \ub2e8\ubc31\uc9c8 \uacb0\ud569\uc5d0 \ub300\ud55c \uac00\uc7a5 \ud569\ub9ac\uc801\uc778 \uc811\uadfc \ubc29\uc2dd\uc740 \ud2b9\uc815 \ubd84\uc790\uc5d0 \ucd08\uc810\uc744 \ub9de\ucd94\uace0 \ub370\uc774\ud130 \uae30\ubc18\uc774\uc5b4\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\uc720\uc6a9\ud55c \uacb0\ud569 \ubc29\ubc95\uc740 \ub2e8\uc21c\ud788 \uac00\uc7a5 \uc798 \uc54c\ub824\uc838 \uc788\uac70\ub098 \uac00\uc7a5 \ud65c\uc131\uc801\uc778 \ucd09\ub9e4\ub97c \uc0ac\uc6a9\ud558\ub294 \ubc29\ubc95\uc774 \uc544\ub2d9\ub2c8\ub2e4. \uc774\ub294 \ubc18\ubcf5\uc801\uc73c\ub85c \ubaa9\uc801\uc744 \uac00\uc9c4 \ubd84\uc790 \uacb0\ud569\uc744 \uc0dd\uc131\ud558\ub294 \ubc29\ubc95\uc774\uba70, \ub3d9\uc2dc\uc5d0 \uc801\uc808\ud55c stereochemical integrity\uc640 \uc81c\uc5b4\ub97c \uc720\uc9c0\ud569\ub2c8\ub2e4. \ud2b9\uc815 \ud569\uc131 \ud3a9\ud2f0\ub4dc\uc5d0 \ub300\ud55c \uc911\uc694\ud55c \uc624\uc5fc\ubb3c\uc9c8.<\/p>\n

\ucc38\uc870<\/h2>\n
    \n
  1. Subir\u00f3s-Funosas, R., Prohens, R., Barbas, R., El-Faham, A., & Albericio, F. (2009). Oxyma: \ud398\ub2c8\ud2b8 \ud569\uc131\uc6a9 \ud6a8\uc728\uc801\uc778 \ucca8\uac00\uc81c\ub85c\uc11c \ud3ed\ubc1c \uc704\ud5d8\uc774 \ub0ae\uc740 benzotriazole \uae30\ubc18 HOBt \ubc0f HOAt\ub97c \ub300\uccb4\ud569\ub2c8\ub2e4. \ud654\ud559\u2014\uc720\ub7fd \uc800\ub110, 15<\/em>(37), 9394\u20139403. https:\/\/doi.org\/10.1002\/chem.200900614<\/a><\/li>\n
  2. \ubbf8\uc57c\uc790\uc640, T., \uc624\ud1a0\ub9c8\uce20, T., \uc57c\ub9c8\ub2e4, T., & \ucfe0\uc640\ud0c0, S. (1992). \ubcf4\ud638\ub41c \uc5d0\ud53c\uba38\ub9ad \ud398\ub2c8\uc2e4\uc758 \uc5ed\ud5a5\uc0c1 \uace0\uc131\ub2a5 \uc561\uccb4 \ud06c\ub85c\ub9c8\ud1a0\uadf8\ub798\ud53c\ub97c \ud1b5\ud55c \ud3a9\ud2f0\ub4dc \ud569\uc131\uc5d0\uc11c\uc758 \ud398\ub2c8\uc2e4\ub9ac\ub124\uc774\ud305 \uc5f0\uad6c. \ud3a9\ud0c0\uc774\ub4dc \ubc0f \ub2e8\ubc31\uc9c8 \uc5f0\uad6c \uad6d\uc81c \uc800\ub110, 39<\/em>(3), 229\u2013236. https:\/\/doi.org\/10.1111\/j.1399-3011.1992.tb00794.x<\/a><\/li>\n
  3. \uce74\ud3ec\ub810\ub808, \uc544., \ub3c4\ud2f0, N., \uc0ac\ub3c4\uba58\ub2c8\ucf54, A., & \ub8e8\ubcf4, M. (2017). \uc624\ud0a4\ub9c8\uc640 \ud558\ud22c\uc758 \uc870\ud569 \uc0ac\uc6a9\uc744 \ud3c9\uac00\ud558\uc5ec \ud3a9\ud2f0\ub4dc \uc11c\uc5f4\uc744 \uc9d1\uacc4\ud558\ub294 \ubc29\ubc95. \ud3a9\ud0c0\uc774\ub4dc \uacfc\ud559 \uc800\ub110, 23<\/em>(4), 272\u2013281. https:\/\/doi.org\/10.1002\/psc.2977<\/a><\/li>\n
  4. \uc57c\ub4dc, Y. E., \ud558\ud0c0\ube73, S. N., \ub370 \ub77c \ud1a0\ub808, B. G., \uace0\ubc84\ub354, T., \ud06c\ub8e8\uac70, H. G., \uc5d8-\ud30c\ud568, A., & \uc54c\ubca0\ub9ac\uc2dc\uc624, F. (2014). \ud398\ub2c8\uc2e4\uc0b0\uc5fc, \ud3a9\ud0c0\uc774\ub4dc \ud569\uc131\uc744 \uc704\ud55c \ud0c1\uc6d4\ud55c \ud658\uc6d0\uc81c. \uc720\uae30 \ubc0f \uc0dd\ubb3c\ubd84\uc790 \ud654\ud559, 12<\/em>(42), 8379\u20138385. https:\/\/doi.org\/10.1039\/c4ob01612b<\/a><\/li>\n
  5. \ucf54\uc778, \uc774., \ubca0\uc774\uc5b4\ub9cc, M., \ube44\uc5d4\ubca0\ub974\ud2b8, M. (2007). \uace0\uccb4\uc0c1 \ubd84\uc790\ud569\uc131: \ud45c\uc900 \uc808\ucc28\uc5d0\uc11c\ubd80\ud130 \ubcf5\uc7a1\ud55c \uc11c\uc5f4\uc758 \ud569\uc131\uae4c\uc9c0. Nature Protocols, 2<\/em>(12), 3247\u20133256. https:\/\/doi.org\/10.1038\/nprot.2007.454<\/a><\/li>\n
  6. \uba38\uae00\ub7ec, M., \ub514\ud06c, F., \uc0ac\ud06c\uc2a4, B., \ube4c\ub7ec, P., & \uc6cc\uc5b4\ud558\ub974, T. (2003). Fmoc \uae30\ubc18 SPPS\uc5d0\uc11c\uc758 \uc544\uc2a4\ud30c\ub974\ud2f0\ubbf8\ub4dc \ubb38\uc81c. \uc81c1\ubd80. \ud3a9\ud0c0\uc774\ub4dc \uacfc\ud559 \uc800\ub110, 9<\/em>(1), 36\u201346. https:\/\/doi.org\/10.1002\/psc.430<\/a><\/li>\n
  7. \uba54\ub974\uae00\ub7ec, M., \ub514\ud06c, F., \uc0ac\ud06c\uc2a4, B., \uc2a4\ud14c\ud5e4\ub9b0, C., & \ubcf4\ub974\ud558\ub974, T. (2003). Fmoc \uae30\ubc18 SPPS\uc5d0\uc11c\uc758 \uc544\uc2a4\ud30c\ub974\ud2f0\ubbf8\ub4dc \ubb38\uc81c. \uc81c2\ubd80. \ud3a9\ud0c0\uc774\ub4dc \uacfc\ud559 \uc800\ub110, 9<\/em>(8), 518\u2013526. https:\/\/doi.org\/10.1002\/psc.473<\/a><\/li>\n
  8. \uc560\ub364\uc2a8, J. G., \ud638\uc559, T., \ud06c\ub9ac\ube44\uce58, A., & \ub77c\uc870\uc774, G. A. (1992). \uc544\ubbf8\ub178\uc0b0\uc744 \uace0\uccb4 \ub9e4\uc9c8\uc5d0 \uacb0\ud569\uc2dc\ucf1c \ud3a9\ud0c0\uc774\ub4dc \ud569\uc131\uc744 \uc218\ud589\ud560 \ub54c \ub9c8\ub974\ud53c\uc774 \ubc18\uc751\uae30\ub97c \uc0ac\uc6a9\ud558\uc5ec \ub77c\uc138\ub9c8\uc774\uc9d5\uc744 \uc815\ub7c9\ud654\ud558\ub294 \ubc29\ubc95. \ubd84\uc11d \uc0dd\ud654\ud559, 202<\/em>(1), 210\u2013214. https:\/\/doi.org\/10.1016\/0003-2697%2892%2990229-z<\/a><\/li>\n
  9. Palasek, S. A., Cox, Z. J., & Collins, J. M. (2007). \ub9c8\uc774\ud06c\ub85c\ud30c\ub97c \uc774\uc6a9\ud55c Fmoc \uace0\uccb4\uc0c1 \ud3a9\ud0c0\uc774\ub4dc \ud569\uc131\uc5d0\uc11c \ub77c\uc138\ubbf8\ud654 \ubc0f \uc544\uc2a4\ud30c\ub974\ud2f0\ubbf8\ub4dc \ud615\uc131\uc744 \uc5b5\uc81c\ud558\ub294 \ubc29\ubc95. Journal of Peptide Science, 13<\/em>(3), 143\u2013148. https:\/\/doi.org\/10.1002\/psc.804<\/a><\/li>\n
  10. \ud30c\uc6b8\ub77c\uc2a4, J., \uc2a4\ubca0\ub974\uc190, T., \uadf8\ub9ac\uace0 \ub77c\uc2a4\ubb34\uc13c, J. H. (2019). \ub179\uc0c9 \ud398\ub2c8\ud2b8 \ub808\uc9c4 \ubd84\ud574\uc5d0 \ub300\ud55c \uc81c\uac70\uc81c\ub85c \uc0ac\uc6a9\ub418\ub294 1,4-\ubca4\uc820\ub370\ubbf8\ud14c\ud0c4\uc774\uc62c (1,4-BDMT). RSC \uc544\ub4dc\uc640\uc774\uce20, 9<\/em>(67), 38928\u201338934. https:\/\/doi.org\/10.1039\/c9ra08553j<\/a><\/li>\n
  11. \ub9e5\ucf08\ub86d, K., \ub370\uc774\ube44\uc2a8, W., \ud578\uc2a8, G., \ud504\ub9ac\uba3c, D., & \ud314\ub77c\uc774, P. (1991). \ubb34\uae30\uc0c1 \ud3a9\ud2f0\ub4dc \ud569\uc131\uc73c\ub85c\ubd80\ud130\uc758 \uc6d0\uc720 \uc81c\ud488\uc758 \ud2b9\uc131\ud654: \ubba4-HPLC\/\ube60\ub978 \uc6d0\uc790 \ubc29\uc804 \uc9c8\ub7c9 \ubd84\uc11d\ubc95. \ud3a9\ud0c0\uc774\ub4dc \uc5f0\uad6c, 4<\/em>(1), 40\u201346. PubMed<\/a><\/li>\n<\/ol>","protected":false},"excerpt":{"rendered":"

    \ud3a9\ud0c0\uc774\ub4dc \uacb0\ud569\uc740 \uce74\ubcf4\ud0a4\uc0b0 \uadf8\ub8f9\uc744 \ud3ec\ud568\ud558\ub294 \uc131\ubd84\uacfc \uc544\ubbfc \uadf8\ub8f9\uc744 \ud3ec\ud568\ud558\ub294 \uc131\ubd84 \uc0ac\uc774\uc758 \uacb0\ud569\uc744 \uc0dd\uc131\ud558\ub294 \ud654\ud559\uc801 \uacfc\uc815\uc785\ub2c8\ub2e4. \uc774 \ubc18\uc751\uc758 \uacb0\uacfc\ub85c \uc544\ubbfc \uacb0\ud569\uc774 \ud615\uc131\ub429\ub2c8\ub2e4.\u2026<\/p>","protected":false},"author":7910,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[305],"tags":[],"class_list":["post-56551","post","type-post","status-publish","format-standard","hentry","category-materialy-edukacyjne","beh-no-thumb"],"_links":{"self":[{"href":"https:\/\/bioevidencehub.com\/ko\/wp-json\/wp\/v2\/posts\/56551","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bioevidencehub.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bioevidencehub.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bioevidencehub.com\/ko\/wp-json\/wp\/v2\/users\/7910"}],"replies":[{"embeddable":true,"href":"https:\/\/bioevidencehub.com\/ko\/wp-json\/wp\/v2\/comments?post=56551"}],"version-history":[{"count":2,"href":"https:\/\/bioevidencehub.com\/ko\/wp-json\/wp\/v2\/posts\/56551\/revisions"}],"predecessor-version":[{"id":56555,"href":"https:\/\/bioevidencehub.com\/ko\/wp-json\/wp\/v2\/posts\/56551\/revisions\/56555"}],"wp:attachment":[{"href":"https:\/\/bioevidencehub.com\/ko\/wp-json\/wp\/v2\/media?parent=56551"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bioevidencehub.com\/ko\/wp-json\/wp\/v2\/categories?post=56551"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bioevidencehub.com\/ko\/wp-json\/wp\/v2\/tags?post=56551"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}