Pt-141

PT-141 (bremelanotide): molecular mechanism, clinical studies, safety and scientific evidence in women and men

Bremelanotyd, often referred to by the research name PT-141, is a cyclic heptapeptide related to the alpha-melanotropic hormone (α-MSH). Its structure is usually represented as Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH. It is also described as cyclo-Ac-[Nle4, Asp5, D-Phe7, Lys10] α-MSH-(4–10). Unlike drugs whose main action is based…